Volume 25, Issue 9 (Nov 2017)
JSSU 2017, 25(9): 690-700 |
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Tajik A, Zirahian F, Shahabi H, Kalani F.
Effects of Exercise Training and Saffron Extract on some of the Predictors of Cardiovascular Diseases
. JSSU 2017; 25 (9) :690-700
URL: http://jssu.ssu.ac.ir/article-1-4161-en.html
URL: http://jssu.ssu.ac.ir/article-1-4161-en.html
Abstract: (5776 Views)
Introduction: The aim of the present research was to investigate the intervention of exercise and saffron supplement on predictors of cardiovascular diseases.
Method: The present research was a semi-experimental and applied study. For this purpose, 40 sedentary women were randomly divided into 4 groups: the control, saffron supplement, resistance training-placebo, and resistance training-saffron extract groups. The subjects performed resistance training protocol for 12 weeks. Also, the supplement group received 40 mg of saffron extract. Anthropometric and experimental evaluations were done before and after 12 weeks as pre-test and post-test to investigate the supplement and training interventions. The statistical tests that were run in this study were one-way analysis of variance (ANOVA) and LSD Post hoc test.
Results: The results showed that there was not any significant difference between the different groups in all variables except triglyceride (P < 0.005). LSD post hoc test showed that there was a significant difference between the control group and training with saffron group in variables of CRP, LDL, and insulin resistance (P < 0.005). Inaddition, there was a difference between saffron group and control group only in variable of LDL (P < 0.005). This indicated the special role of saffron in LDL. On the other hand, the results showed there was a significant difference between training-saffron group and placebo in all the variables except the variable of triglyceride (P < 0.005).
Conclusion: Resistance training with and without saffron supplement within 12 weeks is an efficient way to improve cardiovascular risk factors. Also, saffron supplement along with resistance training has relatively better and more efficient effects.
Method: The present research was a semi-experimental and applied study. For this purpose, 40 sedentary women were randomly divided into 4 groups: the control, saffron supplement, resistance training-placebo, and resistance training-saffron extract groups. The subjects performed resistance training protocol for 12 weeks. Also, the supplement group received 40 mg of saffron extract. Anthropometric and experimental evaluations were done before and after 12 weeks as pre-test and post-test to investigate the supplement and training interventions. The statistical tests that were run in this study were one-way analysis of variance (ANOVA) and LSD Post hoc test.
Results: The results showed that there was not any significant difference between the different groups in all variables except triglyceride (P < 0.005). LSD post hoc test showed that there was a significant difference between the control group and training with saffron group in variables of CRP, LDL, and insulin resistance (P < 0.005). Inaddition, there was a difference between saffron group and control group only in variable of LDL (P < 0.005). This indicated the special role of saffron in LDL. On the other hand, the results showed there was a significant difference between training-saffron group and placebo in all the variables except the variable of triglyceride (P < 0.005).
Conclusion: Resistance training with and without saffron supplement within 12 weeks is an efficient way to improve cardiovascular risk factors. Also, saffron supplement along with resistance training has relatively better and more efficient effects.
Type of Study: Original article |
Subject:
Exercise Physiology
Received: 2017/04/13 | Accepted: 2017/07/29 | Published: 2017/12/9
Received: 2017/04/13 | Accepted: 2017/07/29 | Published: 2017/12/9
References
1. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB , et al. Heart disease and stroke statistics-2013 update. Circulation 2013; 127(1): e6–e245.
2. Mogharnasi M. The effect of endurance training and speed training over a period of cell adhesion molecules (sICAM) and inflammatory mediators (IL-1β, TNF-α) Wistar rats. 1386. Thesis, Faculty of Physical Education, Sport Science, Tehran University.[Persian]
3. Gaeini A, Ghasemnian A, Jalali K, Dehkordi KH, Kazemi AR, Fallahi AA. The Comparison of the effect a single acute exercise on plasma, CRP, TNFα and IL-6 levels in immature obese and normal-weight boys .J Mazandaran Univ. Med Sci 2011; 21(83): 74-78. [Persian]
4. Humphrey LL, Fu R, Rogers K, Freeman M, Helfand M. Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. InMayo Clinic Proceedings . 2008; 83(11): 1203-12.
5. Gomez-Cabrera MC, Salvador-Pascual A, Cabo H, Ferrando B, Viña J. Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training? Free Radical Biology and Medicine 2015 ; 86: 37-46.
6. Akhondzadeh S, Tahmacebi‐Pour N, Noorbala AA, Amini H, Fallah‐Pour H, Jamshidi AH, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double‐blind, randomized and placebo‐controlled trial. Phytotherapy Research 2005; 19(2): 148-51. [Persian]
7. Kamalipour M, Akhondzadeh S. Cardiovascular effects of saffron: An evidence-based review. The J Tehran University Heart Center 2011; 6(2): 59-61. [Persian]
8. Modaresi M, Messripour M. Effect of saffron extract on electrophoretic pattern of serum proteins in the male mice. Scientific J Kurdistan Uni of Med Sci 2009; 13(4): 23-9. [Persian]
9. Moradi Z, Sjemshaki A, Basemi M. Saffron effect of supplementation on changes in levels of superoxide dismutase and catalase during intense anaerobic exercise in young women. The Journal of Exercise Physiology 2011; (14): 119-130. [Persian]
10. Memarbashi A, Hakimi V. Effects of saffron supplementation on the cardio-respiratory endurance in the healthy inactive girls 2014; 2(3): 225-230. [Persian]
11. Asdaq SM, Inamdar MN. Potential of Crocus sativus (saffron) and its Constituent, Crocin, as Hypolipidemic and Antioxidant in Rats, Appl Biochem Biotechnol 2010; 162(2):358–72. [Persian]
12. mocheshi s, almori mr, mocheshi l. interactive effect of grape seed extract along with aerobic activity on lipid profile in inactive obese women aged over 60 years sanandaj. iranian j diabetes and metabolism 2015; 14(4): 273-8. [Persian]
13. Semnani N, shahidi F. The Effect of Four Weeks of Resistance Training Along with Alfalfa Extract on Cathepsin S and Cystatin C Levels in Girls with Weight Loss. J Med Sci Ilam 2016; 24(3): 10-17. [Persian]
14. Kraemer WJ, Ratamess NA. Fundamentals of resistance training: progression and exercise prescription. Med and sci in sports and exercise 2004; 36(4): 674-88.
15. Saghebjoo M, Hedayati M, Fahimi Y, Ilbeigi S. Plasma acylated ghrelin response to one session circuit resistance exercise in fasted and high carbohydrate meal in healthy young men. International j endocrinology and metabolism 2013; 11(4): e8568.
16. mehri ay, ramezani a. the effects of resistance and alternative training on some predictors of heart diseases. Ebnesina - IRIAF Health Administration. Spring 2016; 18(1): 19-28. [Persian]
17. Emamdost S, Faramarzi M. Effect of combined training (resistance exercise) on homocysteine levels and lipid profile in overweight men. Scientific Journal of Kurdistan University of Medical Sciences 2016; 20(N1): 80-88. [Persian]
18. Bahram ME, Najjarian M, Sayyah M, Mojtahedi H. The effect of an eight-week aerobic exercise program on the homocysteine level and VO2max in young non-athlete men. KAUMS J (FEYZ) 2013; 17(2): 149-56. [Persian]
19. Vacek TP, Rehman S, Neamtu D, Yu S, Givimani S, Tyagi SC. Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms. Vascular health and risk management 2015;11:173-83.
20. Ramos JS, Dalleck LC, Tjonna AE, Beetham KS, Coombes JS. The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis. Sports Med 2015; 45(5): 679-92.
21. Gondim OS, de Camargo VT, Gutierrez FA, Martins PF, Passos ME, Momesso CM, et al. Benefits of regular exercise on inflammatory and cardiovascular risk markers in normal weight, overweight and obese adults. PloS one 2015; 10(10): e0140596.
22. Naghizade H, Akbarzade H, NargoniA. Effect of resistance training circle with vitamin C, the changes homocysteine and C-reactive protein and tumor necrosis factor alpha male non-athletes healthy. Res in Sport Sci 2010; 36: 121-132. [Persian]
23. Drager CJ. Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program. Doctoral dissertation, Virginia Polytechnic Institute and State University 2012.
24. Thompson PD, Buchner D, Piña IL, Balady GJ, Williams MA, Marcus BH, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease. Arteriosclerosis, thrombosis, and vascular biology 2003; 107(24): 3109-16.
25. Buchan DS, Ollis S, Young JD, Thomas NE, Cooper SM, Tong TK, et al. The Effects of Time and Intensity of Exercise on Novel and Established Markers of CVD in Adolescent Youth. Am J Hum Biol 2011; 23: 517–526.
26. Nash MS, Jacobs PL, Mendez AJ, Goldberg RB. Circuit resistance training improves the atherogenic lipid profiles persons with chronic paraplegin. J spinal cord med 2001; 24(1): 2-9.
27. Marques E, Carvalho J, Soares J, Marques F, Mota J. Effects of resistance and multicomponent exercise on lipid profiles of older women. Maturitas 2009; 63(1): 84-88
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