Volume 15, Issue 4 (Winter 2008)                   JSSU 2008, 15(4): 16-20 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Barzegar M, Jafari Roohi A. Refractory Status Epilepticus in Children Risk Factors, Management and Early Outcome. JSSU 2008; 15 (4) :16-20
URL: http://jssu.ssu.ac.ir/article-1-616-en.html
Abstract:   (21165 Views)
Introduction: Refractory status epilepticus is a life-threatening disease in children wherein seizure movements don't response to first line anti convulsion drugs. This study reviewed risk factors, management and early outcome of children with refractory status epilepticus. Methods: Patients with refractory status epilepticus admitted in Tabriz children's hospital between 2003 and 2006 were reviewed prospectively for risk factors, management and outcome at time of discharge from hospital. Results: Of the total of 121 patients with status epilepticus, 47 patients (38.8%) were afflicted with refractory status epilepticus. The most common form of refractory status epilepticus was acute symptomatic (38.3%). Seizure caused by acute symptomatic [RR= 2.36, (CI 95%=1.25 – 4.44), P=0.006] was a risk factor for refractory status epilepticus development. 87.2% of patients with refractory status epilepticus were treated by midazolam infusion. There was no significant relation between non-response to midazolam, etiology (P=0.798) and type of seizure (P=0.273). Early outcome of children with refractory status epilepticus was significantly worse than those with status epilepticus (P=0.0001). Conclusion: About 38% of patients with status epilepticus develop refractory status epilepticus with an increased mortality and morbidity. Seizure caused by acute symptomatic is an important risk factor for developing refractory status epilepticus. In most cases, midazolam infusion results in end of seizure.
Full-Text [PDF 106 kb]   (8876 Downloads)    
Type of Study: Original article | Subject: General
Received: 2010/01/25 | Published: 2008/01/15

Add your comments about this article : Your username or Email:

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | SSU_Journals

Designed & Developed by : Yektaweb