Volume 25, Issue 4 (July 2017)                   JSSU 2017, 25(4): 287-299 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Salmani M H, Mikaie M, Torabizadeh H, Rahmanian R. Application of magnetic iron oxide nanoparticles in stabilization process of biological molecules . JSSU. 2017; 25 (4) :287-299
URL: http://jssu.ssu.ac.ir/article-1-3992-en.html
Abstract:   (6528 Views)
Introduction: Because of their unique properties, magnetic nanoparticles have attracted the attention of many researchers in various fields. The stabilization enzyme on functionalized magnetic nanoparticles, with the maintenance of free protein activity and optimal stability, have been developed by various surface modification techniques. This review focused on the methods for  modification of iron magnetic nanoparticles and their application to stabilize protein.
Methods: Among the published valid articles, 51 articles were selected from various scientific databases between the (2000-2016) years. The papers were evaluated for biological, physical and chemical synthesis methods, advantages and limitations of synthesis methods, application of surface modification and enzyme fixation on iron oxide nanoparticles. Precisely analyzing of papers, the most suitable method was investigated for the synthesis of nanoparticles and the use of nanoparticles was summarized in the biomolecules fixation process.
Conclusion: Co-precipitation method is an easy way to prepare magnetic nanoparticles of iron with a large surface and small particle size, which increases the ability of these particles to act as a suitable carrier for enzyme stabilization. Adequate modification of the surface of these nanoparticles enhances their ability to bind to biological molecules. The immobilized protein or enzyme on magnetic nanoparticles are more stable against structural changes, temperature and pH in comparison with un-stabilized structures, and it is widely used in various sciences, including protein isolation and purification, pharmaceutical science, and food analysis. Stabilization based on the covalent bonds and physical absorption is nonspecific, which greatly limits their functionality. The process of stabilization through bio-mediums provide a new method to overcome the selectivity problem.
Full-Text [PDF 874 kb]   (6858 Downloads)    
Type of Study: Review article | Subject: other
Received: 2016/12/7 | Accepted: 2017/05/20 | Published: 2017/09/19

1. Gupta A, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005; 26: 3995–4021.
2. Salmani M H, Ehrampoush M H. Comparison between Ag (I) and Ni (II) removal from synthetic nuclear power plant coolant water by iron oxide nanoparticles. Journal of Environmental Health Science and Engineering 2013; 11: 1–10.
3. Zhao G, Wen T, Yang X, Yang S, Liao J, Hu J, Shao D, Wang X. Preconcentration of U(VI) Ions on Few-Layered Graphene Oxide Nanosheets from Aqueous Solutions. Dalton Transactions 2012; 41: 6182–6188.
4. Sun C, Lee J, Zhang M. Magnetic Nanoparticles in MR Imaging and Drug Delivery. Advanced Drug Delivery Reviews 2008; 60: 1252–1265.
5. Colombie S, Gaunand A, Lindet B. Lysozyme Inactivation under Mechanical Stirring: Effect of Physical and Molecular Interfaces. Enzyme and Microbial Technology 2001; 28: 820–826.
6. Kim J, Gratea J, Wang P. Nanostructures for Enzyme Stabilization. Chemical Engineering Science 2006; 61: 1017–1026.
7. Tischer W, Wedekind F. Immobilized Enzymes: Methods and Applications. Topics in Current Chemistry 1999; 200: 95–126.
8. Zhang S, Gao S, Gao G. Immobilization of β-galactosidase onto Magnetic Beads. Applied Biochemistry and Biotechnology 2010; 160: 1386–1393.
9. Martin C, Kohli P. The Emerging Field of Nanotube Biotechnology. Nature Reviews Drug Discovery 2003; 2: 29–37.
10. Reddy L, Arias J, Nicolas J, Couvreur P. Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility. Pharmaceutical and Biomedical Applications Chemical Reviews 2012; 112: 5818–5878.
11. King J, Williams W, Wilkinson C, McVite S, Chapman J. Magnetic Properties of Magnetite Arrays Produced by the Method of Electron Beam Lithography. Geophysical Research Letters 1996; 23: 2847–2850.
12. Mathur S, Barth S, Werner U, Hernandez-Ramirez F, Romano-Rodriguez A. Chemical Vapor Growth of One-dimensional Magnetite Nanostructures. Advanced Materials 2008; 20: 1550–1554.
13. Itoh H, Sugimoto T. Systematic Control of Size, Shape, Structure, and Magnetic Properties of Uniform Magnetite and Maghemite Particles. Journal of Colloid and Interface Science 2003; 265: 283–295.
14. Salmani M H, Aboueyan M. Ability of iron oxide nanoparticles in ion silver removal from synthetic wastewater.TolooeBehdasht 2011; 3; 62-69.
15. Ehrampoush M H, Miria M, salmani M H. Cadmium removal from aqueous solution by green synthesis iron oxide nanoparticles with tangerine peel extract. Journal of Environmental Health Science and Engineering 2015; 13: 1-9.
16. Mahmoudi M, Sant S, Wang B, Laurent S, Sen T. Superparamagnetic Iron Oxide Nanoparticles (SPIONs): Development, Surface Modification and Applications in Chemotherapy. Advanced Drug Delivery Reviews 2011; 63: 24–46.
17. Liang X, Shi H, Jia X, Yang Y, Liu X. Dispersibility, Shape and Magnetic Properties of Nano-Fe3O4 Particles 2011; 2: 1644-53.
18. Arias J, Lopez M, Ruiz M, Lopez J, Delgado A. Development of Carbonyl Iron/Ethylcellulose Core/Shell Nanoparticles for Biomedical Applications. International Journal of Pharmaceutics 2007; 339: 237–245.
19. Donega C, Liljeroth P, Vanmaekelbergh D. Physicochemical Evaluation of the Hot-Injection Method, A Synthesis Route for Monodisperse Nanocrystals. Small 2005; 12: 1152–1162.
20. Arias J, Reddy L, Couvreur P. Magnetoresponsive Squalenoyl Gemcitabine Composite Nanoparticles for Cancer Active Targeting. Langmuir 2008; 24: 7512–7519
21. Bahmaie M, Abbasi L, Faraji M. Synthesis of Magnetic Nanoparticles (Fe3O4) and Its Application for Extraction and Preconcentration of Drug Sample from Environmental Samples 2013; 8: 29-37.
22. Treccani L, Klein T, Meder F, Pardon K, Rezwan K. Functionalized Ceramics for Biomedical. Biotechnological and Environmental Application. Acta Biomaterialia 2013; 9:7115–7150.
23. Lee H, Lee E, Kim D, Jang N, Jeong Y, Jon S. Antibiofouling Polymer-Coated Superparamagnetic Iron Oxide Nanoparticles as Potential Magnetic Resonance Contrast Agents for in Vivo Cancer Imaging. Journal of the American Chemical Society 2006; 128: 7383–7389.
24. Souza K, Ardisson J, Sousa E. Study of Mesoporous Silica/Magnetite Systems in Drug Controlled Release. Journal of Materials Science 2009; 20: 507–512.
25. Treccani L, Klein T, Meder F, Pardon K, Rezwan K. Functionalized Ceramics for Biomedical. Biotechnological and Environmental Application. Acta Biomaterialia 2013; 9:7115–7150.
26. Zucca P, Sanjust E. Inorganic Materials as Supports for Covalent Enzyme Immobilization: Methods and Mechanisms. Molecules 2014; 19: 14139-14194.
27. Yang H, Zhang S, Chen X, Zhuang Z, Xu J, Wang X. Magnetite-Containing Spherical Silica Nanoparticles for Biocatalysis and BioseparationsAnalytical Chemistry 2004; 76: 1316–1321.
28. Ozturk N, Akgol S, Arısoy M, Denizli A. Reversible Adsorption of Lipase on Novel Hydrophobic Nanospheres. Separation and Purification Technology 2007; 58: 83–90.
29. Mahdizadeh F, Karimi A, Ranjbarian L. Immobilization of Glucose Oxidase on Synthesized Superparamagnetic Fe3O4 Nanoparticles: Application for Water Deoxygenation. International Journal of Engineering Science 2012; 3: 516–520.
30. Bahrami A, Hejazi P. Electrostatic Immobilization of Pectinase on Negatively Charged AOT-Fe3O4 Nanoparticles. Journal of Molecular Catalysis B: Enzymatic 2013; 93: 1–7.
31. Liang Y, Zhang L, Li W, Chen R. Polysaccharide-Modified Iron Oxide Nanoparticles as an Effective Magnetic Affinity Adsorbent for Bovine Serum Albumin. Colloid & Polymer Science 2007; 285: 1193–1199
32. Betancor L, Luckarift H. Bioinspired Enzyme Encapsulation for Biocatalysis. Trends in Biotechnology 2008; 26: 566–572.
33. Guisan J. Immobilization of Enzymes and Cells, 2nd ed.; Humana Press Inc.: Madrid, Spain 2006.
34. Valdes T, Rebolledo A, Sevilla M, Valle P, Bomati O, Fuertes A, Tartaj P. Preparation, Characterization, and Enzyme Immobilization Capacities of Superparamagnetic Silica/Iron Oxide Nanocomposites with Mesostructured Porosity. Chemistry of Materials 2009; 21: 1806–1814.
35. Joshi M, Sidhu G, Pot I, Brayer G, Withers S, McIntosh L. Hydrogen Bonding and Catalysis: A Novel Explanation for How a Single Amino Acid Substitution Can Change the pH optimum of a Glycosidase. Journal of Molecular Biology 2000; 299: 255–279.
36. Zhang Y, Li J, Han D, Zhang H, Liu P, Li C. An Efficient Resolution of Racemic Secondary Alcohols on Magnetically Separable Biocatalyst. Biochemical and Biophysical Research Communications 2008; 365: 609–613.
37. Vijayalakshmi A, Tarunashree Y, Baruwati B, Manorama S.V, Narayana B.L, Johnson R.E.C, Raoa N. M. Enzyme Field Effect Transistor (ENFET) for Estimation of Triglycerides Using Magnetic Nanoparticles. Biosensors Bioelectronics Journal 2008; 23: 1708–1714.
38. Chen J, Lin W. Sol-Gel Powders and Supported Sol-Gel Polymers for Immobilization of Lipase in Ester Synthesis. Enzyme and microbial technology 2003; 32: 801–811.
39. Johnson A.K, Zawadzka A.M, Deobald L.A, Crawford R.L, Paszczynski A.J. Novel Method for Immobilization of Enzymes to Magnetic NanoparticlesJournal of Nanoparticle Research 2008; 10: 1009–1025.
40. Mateo C, Palomo J.M, Fernandez-Lorente G, Guisan J.M, Fernandez-Lafuente R. Improvement of Enzyme Activity, Stability and Selectivity via Immobilization Techniques. Enzyme and Microbial Technology 2007; 40: 1451–1463.
41. Cowan D, Fernandez-Lafuente R. Enhancing the Functional Properties of Thermophilic Enzymes by Chemical Modification and Immobilization. Enzyme and Microbial Technology 2011; 49: 326–346.
42. Hernandez K, Fernandez-Lafuente R. Control of Protein Immobilization: Coupling Immobilization and Site-Directed Mutagenesis to Improve Biocatalyst or Biosensor Performance. Enzyme and Microbial Technology 2011; 48:107–122.
43. Barbosa O, Torres R, Ortiz C, Berenguer-Murcia A, Rodrigues R, Fernandez-Lafuente R. Heterofunctional Supports in Enzyme Immobilization: From Traditional Immobilization Protocols to Opportunities in Tuning Enzyme Properties. Biomacromolecules 2013; 14: 2433–2462.
44. Wang H, Huang J, Wang C, Li D, Ding L, Han Y. Immobilization of Glucose Oxidase Using CoFe2O4/SiO2 Nanoparticles as Carrier. Applied Surface Science 2011; 257:5739–5745.
45. Kuo C. H, Liu Y, Chang C, Chen J, Chang C, Shieh C. Optimum Conditions for Lipase Immobilization on Chitosan-Coated Fe3O4 Nanoparticles. Carbohydrate Research 2012; 87: 2538–2545.
46. Singh R K, Tiwari M K, Singh R, Lee J. K. From Protein Engineering to Immobilization: Promising Strategies for the Upgrade of Industrial Enzymes. International Journal of Molecular Sciences 2013; 14: 1232-1277.
47. Xu J, Ju C, Sheng J, Wang F, Zhang Q, Sun G, Sun M. Synthesis and Characterization of Magnetic Nanoparticles and Its Application in Lipase Immobilization. Bulletin of the Korean Chemical Society 2013; 34:2408–2012.
48. Dong J, Kun Z, Tang T, Ai S. Enzyme-Catalyzed Removal of Bisphenol A by Using Horseradish Peroxidase Immobilized on Magnetic Silk Fibroin Microspheres. Research Journal of Chemistry and Environment 2011; 15: 13–18.
49. Ma Z, Liu X, Guan Y, Liu H. Superparamagnetic Silica Nanoparticles with Immobilized Metal Affinity Ligands for Protein Adsorption. Journal of Magnetism and Magnetic Materials 2006; 301: 469–477.
50. Merbach A, Toth E. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging. Wiley Chichester. 2nd ed.UK; John Wiley & Son; 2001.
51. Cao M, Li Z, Wang J, Ge W, Yue T, Li R. Food Related Applications of Magnetic Iron Oxide Nanoparticles: Enzyme Immobilization, Protein Purification, and Food Analysis. Trends in Food Science and Technology 2012; 27: 47–56.
52. Kumar S, Jana A, Dhamija I, Singla Y, Maiti M. Preparation, Characterization and Targeted Delivery of Serratiopeptidase Immobilized on Amino-Functionalized Magnetic Nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 2013; 85: 413–426.
53. Lee C, Lee H, Westervelt R. Microelectromagnets for the Control of Magnetic Nanoparticles. Applied Physics Letters 2001; 79: 3308–3310.

Add your comments about this article : Your username or Email:

Send email to the article author

© 2021 CC BY-NC 4.0 | SSU_Journals

Designed & Developed by : Yektaweb