Volume 25, Issue 3 (Jun 2017)                   JSSU 2017, 25(3): 241-251 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Gholipur A, Ansari N, Sadegh Damavandi M, Rabiei M, Mirnezhad R. Genotyping and antibiotic resistance of Acinetobacter baumannii strains isolated from patients hospitalized in teaching hospitals of Shahrekord by Pulsed- Field Gel Electrophorsis . JSSU 2017; 25 (3) :241-251
URL: http://jssu.ssu.ac.ir/article-1-3943-en.html
Abstract:   (5562 Views)
Introduction: Acinetobacters especially Acinetobacter baumannii causing nosocomial infections in hospitals intensive care units and can cause a variety of hospital infections such as bacteremia, meningitis, pneumonia and urinary tract infections. There are several molecular techniques for microbial genotyping, among them Pulsed- Field Gel Electrophoreses is introduced as the gold standard for sub typing of bacteria. The aim of this study  was investigating the molecular typing of A. baumannii strains with PFGE as well as the relationship between common types available and their antibiotic resistance.
Methods: In this descriptive - analysis study, 50 Acinetobacter baumannii were confirmed with cultivation methods and biochemical tests. Then, bacteria were detected using PFGE typing and the results were compared with the results of antibiotic resistance.
Results: The results showed that all isolates had multiple resistance. The highest sensitivity was observed for tobramycin (52%), gentamicin (36%) and moropenem (32%).The results of this study showed that A. baumannii strains isolated from Shahrekord hospitals were in seven different genetic patterns that two of these patterns were sporadic and the genetic patterns were different in each hospital.
Conclusion: Although variations among strains of Acinetobacter baumannii were observed by using PFGE in Shahrekord, but no epidemic strain was detected among them. In terms of resistance to commonly used antibiotics were also different patterns.
Full-Text [PDF 751 kb]   (2129 Downloads)    
Type of Study: Original article | Subject: Microbiology
Received: 2016/10/28 | Accepted: 2017/02/18 | Published: 2017/08/13

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | SSU_Journals

Designed & Developed by : Yektaweb