Volume 25, Issue 8 (Oct 2017)                   JSSU 2017, 25(8): 621-628 | Back to browse issues page

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Ghasemi M, Talebi A, Rahmanyan M, Nahangi H, Ghanizadeh T. Effects of Diabetes Mellitus type 2 on Semen Parameters. JSSU 2017; 25 (8) :621-628
URL: http://jssu.ssu.ac.ir/article-1-3739-en.html
Abstract:   (4435 Views)
Introduction: Diabetes Mellitus (DM) is a chronic metabolic disease that affects all the physiological systems of the body and recently, the age of suffering from DM has decreased. The aim of this study was to assess the semen parameters of males with DM type 2 and non-diabetic males without any metabolic disorders.
Methods: This study was a case-control study. In this study, semen samples were taken from19 male patients with DM type 2 as the case group, and 29 male non-diabetic males as the control group. Semen samples analyzed according to the standards of WHO (volume, count, motility and morphology).
Results: Assessment of semen parameters in the case and control groups showed that progressive motility, count and morphology decreased significantly. There was no significant decrease in volume of semen samples.
Conclusions: Our results showed that DM type 2 has detrimental effects on semen parameters and it can reduce male fertility potential in men with DM type 2.
Full-Text [PDF 622 kb]   (3658 Downloads)    
Type of Study: Original article | Subject: Anatomy
Received: 2016/05/23 | Accepted: 2017/05/20 | Published: 2017/12/5

References
2. Association AD. Diagnosis and classification of diabetes mellitus. Diabetes care 2010; 33(Supplement 1): 81-90.
3. Whiting DR، Guariguata L، Weil C، Shaw J. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes res and clinical practice 2011; 94(3): 311-21.
4. Soudamani S، Malini T، Balasubramanian K. Effects of streptozotocin-diabetes and insulin replacement on the epididymis of prepubertal rats: histological and histomorphometric studies. Endocrine res 2005; 31(2): 81-98.
7. Hussien Z، Al-Qatsi J. Effect of diabetes mellitus type 2 on pituitary gland hormones (FSH، LH) in men and women in Iraq. J Al-Nahrain Uni 2012; 15(3): 57-79.
8. Rezvani MR، Saadatjou SA، Sorouri S، Hassanpour Fard M. Comparison of serum free testosterone، luteinizing hormone and follicle stimulating hormone levels in diabetics and non-diabetics men-a case-control study. J res in health sci 2012; 12(2): 98-100.
9. Vignon F، Le Faou A، Montagnon D، Pradignac A، Cranz C، Winiszewsky P، et al. Comparative study of semen in diabetic and healthy men. Diabete & metabolisme 1990; 17(3): 350-4.
10. Rama Raju G، Jaya Prakash G، Murali Krishna K، Madan K، Siva Narayana T، Ravi Krishna C. Noninsulin‐dependent diabetes mellitus: effects on sperm morphological and functional characteristics، nuclear DNA integrity and outcome of assisted reproductive technique. Andrologia 2012; 44(s1): 490-8.
11. Sexton WJ، Jarow JP. Effect of diabetes mellitus upon male reproductive function. Urology 1997; 49(4): 508-13.
13. Agbaje I، Rogers D، McVicar C، McClure N، Atkinson A، Mallidis C، et al. Insulin dependant diabetes mellitus: implications for male reproductive function. Human Reproduction 2007; 22(7): 1871-7.
14. Mangoli E، Talebi AR، Anvari M، Pourentezari M. Effects of experimentally-induced diabetes on sperm parameters and chromatin quality in mice. Iranian journal of reproductive medicine 2013; 11(1): 53. [persion]
15. Vignera S، Condorelli R، Vicari E، D'Agata R، Calogero AE. Diabetes mellitus and sperm parameters. J andrology 2012; 33(2): 145-53.
16. Amaral S، Moreno AJ، Santos MS، Seiça R، Ramalho-Santos J. Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes. Theriogenology 2006; 66(9): 2056-67.
18. Organization WH. WHO laboratory manual for the examination and processing of human semen. 2010.
19. Baker K، Li J، Sabanegh E. Analysis of semen parameters in male referrals: impact of reference limits، stratification by fertility categories، predictors of change، and comparison of normal semen parameters in subfertile couples. Fertility and sterility 2015; 103(1): 59-65.
20. La Vignera S، Condorelli R، Di Mauro M، Lo Presti D، Mongioì L، Russo G، et al. Reproductive function in male patients with type 1 diabetes mellitus. Andrology 2015; 3(6): 1082-7.
21. Ali S، Shaikh R، Ashfaqsiddiqi N، Siddiqi P. Serum and urinary levels of pituitary-gonadal hormones in insulin-dependent and non-insulin-dependent diabetic males with and without neuropathy. Archives of andrology 1993; 30(2): 117-23. [persion]
22. Delfino M، Imbrogno N، Elia J، Capogreco F، Mazzilli F. Prevalence of diabetes mellitus in male partners of infertile couples. Minerva urologica e nefrologica. The Italian J urology and nephrology 2007; 59(2): 131-5.
23. Boucher D، Hermabessiere J، Grizard G، Doly M، Bruhat M. Investigation of the gonadotrophins and prolactin in sterile men (the LH-RH+ TRH test)(author's transl). Revue française de gynécologie et d'obstétrique 1977; 72(10): 631.
24. Kapoor D، Aldred H، Clark S، Channer KS، Jones TH. Clinical and Biochemical Assessment of Hypogonadism in Men With Type 2 Diabetes Correlations with bioavailable testosterone and visceral adiposity. Diabetes care 2007; 30(4): 7-911.

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