Molanouri Shamsi, Alinejad, Amani Shalamzari, Aghayari, Asghari Jafarabadi, Talebi Badrabadi. Anti-Inflammatory Effects of a Bout of Circuit Resistance Exercise With Moderateintensity in Inactive Obese Males. JSSU 2011; 19 (5) :598-609
URL:
http://jssu.ssu.ac.ir/article-1-1735-en.html
Abstract: (13596 Views)
Introduction: Obesity is a state characterized by a low-grade inflammation that leads to insulin resistance. The aim of the present study was to assess serum interleukin-18 (IL-18), interleukin-6 (IL-6), C-reactive protein (CRP) and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) in response to circuit resistance exercise in obese and normal-weight subjects with different levels of physical activity.
Methods: Thirty-two healthy male students participated in the present study. Subjects were divided into 4 groups according to their BMI and level of physical activity: active obese (n=8), active non-obese (n=8), inactive obese (n=8), and inactive non-obese (n=8). To determine serum IL-6, IL-18, CRP, glucose and insulin concentrations, fasting and post-exercise blood samples were obtained. Subjects performed a bout of circuit resistance exercise in 2 sets with 10 repetitions at 60% of 1RM.
Results: Obese subjects comparing non-obese ones showed significant increase in IL-6 and significant decrease in IL-18 concentrations in response to exercise (p<0.05). There was no significant difference between active normal and inactive normal subjects in response to exercise. Also, there were not significant differences in four groups in response to exercise.
Discussion: The significant decrease in IL-18 concentration in the obese group comparing normal group in response to exercise was probably due to anti-inflammatory effects of exercise. Also, recommending this kind of exercise for obese persons with low level of physical activity can improve insulin resistance.
Type of Study:
Original article |
Subject:
General Received: 2011/12/12 | Published: 2011/12/15