Volume 12, Issue 4 (winter 2005)                   JSSU 2005, 12(4): 10-18 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Salman Roughani H. Prevalence of Hepatitis B Cab with or Without Anti Hbsab in Hbsag Seronegative Blood Donors. JSSU. 2005; 12 (4) :10-18
URL: http://jssu.ssu.ac.ir/article-1-1374-en.html
Abstract:   (23525 Views)
Introduction: There are multiple reports of Acute Hepatitis B after blood transfusion inspite of good screening for Hepatitis B before transfusion. Therefore, occult hepatitis B is a serious concern for Blood transfusion. There is a lot of evidence that positive HBCAb in seronegative HBSAg blood donors is associated with occult Hepatitis B. Aim: Evaluation of the prevalence of HBCAb in seronegative HBSAg blood donors. Method: In a cross sectional descriptive study, we evaluated the serum of 1230 Blood donors for HBCAb, HCVAb and Aminotranferase levels. HBSAg or AntiHIV Ab positive cases were excluded from the study. Detection of Anti HBSAb was done in HBCAb positive patients and liver biopsy was performed in all HCVAb positive cases. Results: 15.1% of blood donors were positive for HBCAb and 51.6% of them had Anti HBSAb. Aminotranferase levels were normal in all people who were positive for HBCAb ,but about 50% of HCVAb positive persons had elevated aminotransferase levels and liver biopsy of all these patients showed inflammation Conclusion: Prevalence of HBCAb is high in our seronegative HBSAg Blood donors and biomolecular studies such as PCR for HBV DNA is indicated in HBCAb positive people, especially in people with isolated HBCAb .
Full-Text [PDF 185 kb]   (34966 Downloads)    
Type of Study: Original article | Subject: General
Received: 2011/02/5 | Published: 2005/01/15

Add your comments about this article : Your username or Email:

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | SSU_Journals

Designed & Developed by : Yektaweb