Showing 30 results for Type 2
F Kaseb, Mh Soltani, M Kimiagar, M Hoseini,
Volume 12, Issue 2 (7-2004)
Abstract
Introduction: It is felt that there is an information void regarding the effect of macronutrients on cardiovascular responses such as cardiac output,heart rate,stroke volume,systolic blood pressure,diastolic blood pressure and mean arterial pressure, therefore, this study was designed to explore these effects at Shaheed Beheshti University in 2001.
Materials & Methods: This clinical trial was carried out on 10 healthy subjects and 15 type 2 diabetics. Cardiovascular responses defined before and 15,30,60,90 and 120 minutes after the intake of wheat starch,sodium caseinat and olive oil. The calorie level was 10 kcal per kg of ideal body weight.
Statistical analyses were done by analysis of variance with repeated measures, independent - t test and dependent- t test.
Results : The age of healthy subjects (4 women ,6men)was 36.6±5.8(mean±SD)yr,body mass index was 24±1.2Kg/m² , age for the type 2 diabetics (4 women ,11men)was 38.9±5.2(mean ±SD )yr , body mass index was 24±1.6Kg/m². In healthy subjects, macronutrients caused marked and gradually developing postprandial increases in cardiac output, while in type 2 diabetics,cardiac output had no changes. In healthy subjects, systolic blood pressure and mean arterial pressure rose after the ingestion of macronutrients (P<0.05). In type 2 diabetics after the ingestion of macronutrients there was a fall in systolic blood pressure and mean arterial pressure(P<0.05).In both groups, diastolic blood pressure showed no changes .
Conclusion: There were considerable differences in the speed of development and the pattern of the cardiovascular responses between type 2 diabetics and healthy subjects (P<0.05).Finally we conclude that diabetes in the early stages probably involves the cardiovascular system.
B Mohammadi, A Hassanzadeh,
Volume 19, Issue 5 (12-2011)
Abstract
Introduction: This study analyses the risk factors that affect glycosylated hemoglobin index in type 2 diabetes mellitus. The purpose of this study was to determine the relative importance of each factor and design a polynomial model for predicting blood glucose levels according to the factors influencing it.
Methods: In this study, risk factors including weight, systolic and diastolic blood pressure, total cholesterol level and high-density lipoprotein level, were assessed among 403 subjects(170 males and 233 females) with age range of 19 to 75 years-old through interviews and tests. Then using Response Surface Methodology(RSM) technique that is based on the regression analysis, the most important risk factors effective on glycosylated hemoglobin index were determined and a polynomial model was introduced for predicting the level of this index.
Results: The results show that at least 78 percent of changes of glycosylated hemoglobin index are described by risk factors of weight, systolic and diastolic blood pressure, total cholesterol, high-density lipoprotein, and remaining changes depend on other risk factors and genetic factors. Owing to these results, it can be declared that in men high-density lipoprotein and weight have the most and the least impact on the index value, respectively while in women diastolic blood pressure and cholesterol level have the most and the least impact on the index value, respectively.
Khorshidi, Matinhomaee, Azarbayjani , Hossein-Nezhad ,
Volume 19, Issue 5 (12-2011)
Abstract
Introduction: The purpose of this study was to investigate the effects of a ten week period of aerobic exercise training on serum alkaline phosphates and osteocalsin in type 2 diabetic patients.
Methods: In a quasi-experimental trial study twenty one male patients with type 2 diabetes(40-50 years) were randomly divided into exercise(n=11) and control(n=10) groups. The exercise group underwent a 10-week aerobic exercise program(three sessions per week, 45-60 minutes each session, at 50-65% of heart rate reserve). VO2max, BMI, fasting blood glucose and serum insulin, alkaline phosphatase and osteocalcin were measured at baseline and after exercise program.
Results: Exercise program resulted in a significant increase in VO2max and a significant decrease in BMI, fasting blood glucose and HbA1c in exercise group however, no significant changes were found in the insulin concentration, alkaline phosphatase and osteocalcin. The bone formation markers and other measured variables did not show significant change in control group.
Conclusion: These results suggest that aerobic exercise leads to glycemic improvement in type 2 diabetic patients, but does not affect serum levels of alkaline phosphatase and osteocalcin.
A Ravasi, F Kazemi, A Rajab, M Radkani,
Volume 19, Issue 6 (3-2012)
Abstract
Introduction: Type 2 diabetes is a common disease in the world. Exercise has consistently been shown to improve glucose control. The purpose of this study was to compare the effect of a single-session aerobic and resistance exercise on blood glucose in women with type 2 diabetes.
Methods: Twenty four women with type 2 diabetes were voluntarily and randomly selected and divided into aerobic exercise, resistance exercise and control groups. Aerobic exercise(rhythmic exercise) was performed for 40 min at 60% HRmax and resistance exercise(weight lifting) for 40 min utilizing 60% of 1-RM. Blood samples were collected before and after exercise.
Results: Results of paired sample t-test showed a single-session aerobic and resistance exercise significantly decreased blood glucose(p<0.05). ANOVA test found a significant difference in blood glucose among three groups(p<0.05).
Conclusion: A single-session aerobic and resistance exercise could decrease blood glucose in women with type 2 diabetes. However, a single-session aerobic exercise is more effective than resistance exercise on decreasing blood glucose.
H Zahednezhad, H Poursharifi, J Babapour,
Volume 20, Issue 2 (6-2012)
Abstract
Introduction: One of the important challenges in patient with chronic diseases specially diabetes is adherence to therapy of treatment. While the patients don’t follow the treatment program, They get into critical consequences like relapse of illness, intensification of disability, necessity of emergency and hospitalization. So the present study intended to investigate the relationship between health locus of control, slip memory and physician – patient relationship with aherence to therapy.
Methods: To carry out this research, 115 adults with type Π diabetes(men and women) who had referred to Glands clinic of Sina hospital in Tabriz from June to August 2010, completed the following five research questionnaires: demographic information questions, patient – doctor relationship questionnaire(PDRQ-19), General Aherence to therapy Scale(GAS), Prospective and retrospective memory questionnaire(PRMQ), and Multidimensional health locus of control(MHLC). In order to analyze the data, both descriptive and inferred statistics were applied including Pearsons correlation coefficient and multiple regression analysis methods.
Results: The study findings indicated that there exist a positive significant relation between external health locus of control(other- powerful), internal health locus of control and desired physician- patient relationship with adherence to therapy in diabetic patients of type Π. However, results revealed a negative significant relationship between slip memory and adherence to therapy.
Conclusion: The study results proposed that the patients with diabetes type Π, who regard more powerful individuals as responsible for their health like their physician, believe in their own role in control of their health in the second place. Furthermore, they had a desired relationship with their physicians, showed less slip memory, and displayed more adherence to therapy.
B Talaei, H Mozaffari-Khosravi , Ba Jalali , M Mahammadi, A Najarzadeh, H Fallahzadeh,
Volume 20, Issue 3 (8-2012)
Abstract
Introduction: Nowadays there is an uprising trend toward new approaches in type 2 diabetes management. In this study the effect of ginger supplementation on blood glucose, lipid and lipoproteins was examined in diabetic patients. Methods: 81 patients with type 2 diabetes participated in this randomized clinical trial study within two-month interval. Patients were randomly divided into two groups: Placebo (PG) and supplemented (SG). SG group were supplemented with 3 capsules (1g ginger powder in each capsule) and PG group received 3 microcrystalline cellulose capsules each day. Fasting blood glucose(FBS), fructose-amine, HbA1c, total cholesterol, triglycerides, LDL-c, HDL-c and Apolipoproteins (Apo) A1 and B100 were measured before and eight weeks after intervention. Results: Mean of LDL-c in SG before and after supplementation were 112.52 ± 22.09 and 106.10±20.78mg/dl(P=0.03), respectively. Also the results showed significant difference in levels of Apo A1 in SG and PG in the beginning and end of trial(P‹0.005). However no significant differences between groups were observed. Moreover no significant disparities were observed in level of Apo B100, total cholesterol, triglycerides and HDL-c at the same period in studied groups. Mean FBS level after intervention in SG showed a 10.5% decrease(P=0.003), meanwhile a 21% increase in PG (P=0.01) was reported. Changes in mean HbA1c had a similar trend with mean FBS. Conclusion: This study indicates that ginger supplementation for type 2 diabetic patients would improve LDL-c, APO A1, fasting plasma glucose and HbA1c parameters
A Rashidlamir, A Alizadeh, A Ebrahimiatri, M Dastani ,
Volume 20, Issue 5 (1-2013)
Abstract
Introduction: Cinnamon as an herbal medicine has the ability to reduce blood glucose and lipoproteins in diabetic patients. Based on the positive effects of exercise on diabetic patients, the present study was conducted to investigate the effect of Four weeks Period aerobic exercise alongside using cinnamon on lipoprotein parameters and blood glucose in women with type 2 diabetes.
Methods: Thirty diabetic women were voluntarily selected and were randomly divided into three groups: 1) aerobic exercise group 2) aerobic exercise alongside using cinnamon and 3) control group. Aerobic exercise took four weeks with 60 percent of maximum heart rate. Blood samples were collected at the beginning and end of the study.
Results: Blood glucose, the fat percentage and HDL, and the ratio of LDL to HDL in the first group significantly decreased and in the second group increased (P<0.05). Also the first group showed a significant reduction in triglyceride. The only significant change observed in the control group was a significant increase in the level of LDL. Comparing the first and second group, it was observed that in the second group the level of total cholesterol decreased and the ratio of LDL to HDL increased (P<0.05).
Conclusion: Using cinnamon alongside aerobic exercise is likely to be beneficial in regulating the concentration of blood glucose and lipids in diabetic patients.
L Kohan, M Nasiri, A Habib, A Bolhasani,
Volume 21, Issue 1 (4-2013)
Abstract
Introduction: Leptin, the obese (ob) gene product, is a cytokine-like hormone secreted mainly from adipose tissue acting on a receptor site in the hypothalamus to inhibit food intake and stimulate energy expenditure. A G-2548G polymorphism in the leptin gene promoter has a strong influence on leptin gene expression and adipose tissue secretion. The aim of this study was to examine the association of the leptin G-2548A promoter polymorphism with leptin plasma level and susceptibility to type 2 diabetes.
Methods: 100 patients with type 2 diabetes mellitus and 100 healthy controls were screened for the presence of G-2548A polymorphism using PCR-RFLP analysis. Body mass index, fasting leptin and fasting glucose were also determined.
Results: Carriers with the GG genotype (20.02±5.6μg/L) had significantly (P<0.001) higher leptin levels than those with the AG genotypes (16.2±5.4μg/L) and AA genotypes (13.42±6.3). Also, LEP -2548GG genotype presented an increased risk of type 2 diabetes (OR: 3.26, 95%CI: 1.5-7.2, P=0.004). In the other words, GG genotypes in the region of -2548 are associated with increased risk of type 2 diabetes.
Conclusion: The present study showed that G-2548A LEP polymorphism is important in regulating leptin plasma level and is associated with risk of type 2 diabetes. Thus, this polymorphism may act as a molecular marker for type 2 diabetes.
M Fakoori Jouibari, P Farzanegi, Ar Barari,
Volume 22, Issue 1 (4-2014)
Abstract
Introduction: Influence of physical activity with supplement consumption on the decrease of free radicals effects is not well known during exercise. Purslane is one of the richest sources of omega-3 fatty acid. Thus, the purpose of this study was to investigate the effect of 8-week exercise with Purslane consumption on peroxidant and antioxidants indicators (MDA, SOD, CAT) in women with type 2 diabetes.
Methods: 28 sedentary women with type 2 diabetes participated in this study with average age of 50 years and with no history of regular exercise that were randomly divided into 4 groups: control (C), exercise (E), supplementation (S) and exercise + supplementation (E+S). Training programs were 60-75 minutes of aerobic exercise, 3 times in week with 50-70% of maximal heart rate. S and E+S groups consumed 5gr of Purslane seeds with lunch and performed aerobic exercise after 3 hours. Also, 2/5 gr Purslane was consumed with dinner. Blood samples were taken in two phases (before and after 8 weeks) following 12 to 14 hours of being fasted.
Results: MDA decreased significantly, but SOD and CAT levels increased significantly in E, S, E+S groups after 8 weeks (P> 0/05). Also there was a significant difference between MDA in E and E+S groups after 8 weeks (P=0/015).
Conclusion: The results showed that regular aerobic exercise with Purslane consumption can improve peroxidant and antioxidant balance in women with type 2 diabetes and prevent exercise-induced oxidative stress and also diabetes.
M Mirhosseini, F Esfarjani, M Marandi, Sh Khalilzadeh, H Mirhosseini,
Volume 22, Issue 1 (4-2014)
Abstract
Introduction: Progressive natural history and complications of diabetes emphasize the need to adopt appropriate therapeutic strategies. Therefore, this study aimed to investigate the effect of yoga on body composition, blood glucose, HbA1c, Cutaneous fat percentage, and VO2max of type 2 diabetic patients.
Methods: In this quasi-experimental study, 30 men with mean age of 49/30±5/40 years in Yazd were purposefully selected via a convenience sampling and divided into two groups of experimental and control(15 each). Experimental group began the yoga exercises for 12 weeks and 3 sessions per week for 60 minutes, whereas the control group did not receive any regular physical activity. In this study, several variables were measured before and after 12 weeks in both groups including fasting blood sugar (fbs),
2 hour glucose (IIh.pp), glycosylated hemoglobin (HbA1c), aerobic power (VO2max) and Cutaneous fat percentage. In order to measure fbs, IIh.pp, HbA1c, 10 cc of fasting blood and 10 cc of blood 2 hours after breakfast were collected from the subjects in Yazd Diabetes Center. Racopurt test was used to measure VO2max and Lange caliper was applied to measure Cutaneous fat percentage. Moreover, in order to compare the changes between the two groups, mean differences were analyzed using T-test.
Results: No significant difference was observed in levels of fbs, IIh.pp, HbA1c, VO2max and Cutaneous fat percentage in the experimental group compared with the control group (p< 0/05).
Conclusion: Yoga exercises (for 12 weeks) can be effective on controlling the blood glucose in type 2 diabetic patients.
Dr A Haerian Ardakani, Dr Y Asadi, Dr M Afkhami Ardakani, Dr M Nooorelahi, Dr A Sooratgar,
Volume 22, Issue 4 (10-2014)
Abstract
Introduction: The present study aimed to evaluate the Effect of topical tetracycline gel application with non surgical periodontal therapy on HbA1c and lipid profile in type 2 diabetic patients.
Methods: A total of 30 type 2 diabetic patients were randomly divided into two groups. The first group received scaling and root planning, whereas the second group received scaling and root planning with topically applied tetracycline gel. Clinical factors such as GI, PI, PPD and biochemical factors such as HbA1c and lipid profile were assessed in beginning of study and 3 months later.
Results: Comparing the clinical factors between the two groups revealed that periodontal pocket depth significantly reduced in tetracycline-received group. Regarding the biochemical factors, triglyceride levels decreased significantly in tetracycline-received group. No significant difference was observed between the two groups in regard with other clinical and biochemical factors.
Conclusion: The study findings demonstrated that clinical and biochemical parameters have been improved after non surgical periodontal treatment in both groups. Although it seems that application of topical tetracycline gel combined with non-surgical periodontal therapy is effective in improvement of some clinical and biochemical factors like PPD and TG, it doesn’t offer any superiority in regard with other factors compared to mere non surgical periodontal therapy.
R Bashiri, A Ghadiri-Anari, H Hekmatimoghadam, A Dehghani, A Najarzadeh,
Volume 22, Issue 5 (12-2014)
Abstract
Introduction: Type 2 diabetes is regarded as the most common and the most important metabolic disease which is progressively increasing in different societies. In this study, the effect of apple vinegar on lipid profiles and anthropometric indices was examined in Type 2 diabetes patients with dyslipidemia.
Methods: Sixty-two Type 2 diabetic patients with dyslipidemia were randomly assigned into a control (n=30) and an experimental group(n=32). The experimental group was instructed to use 10 cc of apple vinegar soluble in a glass of water two times a day 1 hr before each meal for 8 weeks.
Results: The participants’ serum lipid profiles( Cholesterol, TG,LDL and HDL) and also anthropometric indices(Weight, Height and Waist Circumference) were measured before and after the intervention. Finally, in spite of a reducing trend in cholesterol and LDL in apple vinegar group, no significant differences were observed between the two groups (pvalue>0/05).
Conclusion: The present study revealed that consuming 20 cc of apple vinegar daily had no effect on serum lipoprotein profiles and anthropometric indices in Type 2 diabetes patients with dyslipidemia.
F Mohammadi, M Veissi, F Haidari, H Shahbazian, M Mohammad Shahi,
Volume 22, Issue 6 (2-2015)
Abstract
Introduction: Cardiovascular disease is more prevalent in patients with type 2 diabetes. Regarding the role of probiotics in control of inflammation and modulating the lipid profile, this study assess the effect of probiotic and conventional yogurt on inflammatory markers and lipid profile in type 2 diabetic patients.
Methods: Forty- four subjects with type 2 diabetes were randomly assigned to two intervention and control groups. The intervention group consumed 300 g/d probiotic yogurt (enriched with Lactobacillus acidophilus La-5 and Bifidobacterium lactis Bb-12) and the other consumed 300g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intakes, inflammatory markers and lipid profile were evaluated before and at the end of intervention.
Results: The consumption of probiotic yogurt significantly decrease in glycosylated hemoglobin (HbA1c,p=0.032). Also, TNF-α levels and atherogenic indices (LDL-c / HDL-c) reduced in intervention group at the end of the study (p=0.040 and P= 0.002, respectively). There was a significant increase in HDL-c in probiotic group (p=0.007). No significant changes were observed in biochemical parameters in conventional yogurt (P> 0.05 ).
Conclusion: Consumption of probiotic yogurt improved lipid profile and some inflammatory biomarkers in patients with type 2 diabetes. Also, probiotic yogurt caused significant decrease in HbA1c. It is suggested that probiotic yogurt may be used as an adjunct therapy to reduce the cardiovascular disease risk factors in type 2 diabetes mellitus patients
Mt Afshounpour, Z Davoodi , H Habibi , R Ranjbar , S Shakerian ,
Volume 23, Issue 8 (11-2015)
Abstract
Introduction: Resistin, as a novel adipocytokine, is associated with type 2 diabetes. The present study aimed to determine the effect of circuit resistance exercise training on plasma resistin concentration and insulin resistance in type 2 diabetic men.
Methods: In this applied experimental study, 24 type 2 diabetic men were selected and randomly assigned into two exercise (n = 15, aged 46.40 ± 3.02 yrs) and control (n = 12, aged 45.06 ± 3.86 yrs) groups. Exercise training was performed in eight weeks, 3 days a week with intensity corresponding to 30-70% 1RM. Before and after exercise, levels of plasma resistin, insulin, blood glucose, HBA1c and HOMA-IR after a 12-h fasting were measured. Following the second blood sampling, data analysis was performed using T-test which, p Value <0.05 was considered significant.
Results: The study findings demonstrated a significant differnce between the exercise and control groups (p&le0.05) in regard with plasma resistin (p&le0.002), insulin levels (p&le0.001), HOMA-IR (p&le0.001), fasting blood glucose (FBG) (p&le0.001) and HBA1c (p&le0.038).
Conclusion: It seems that circuit resistance exercise training can produce significant effects on plasma resistin and insulin resistance in type 2 diabetic men. Moreover, resistin level might be associated with insulin resistance in type 2 diabetic men.
L Seifi, F Daryanoosh, M Samadi,
Volume 24, Issue 1 (4-2016)
Abstract
Introduction: Adipocytokine including chemerin and visfatin have a key role in metabolic regulations, as well as obesity-related disorders such as type 2 diabetes. The aim of this study was to investigate the effect of the 12-week exercise training on changes in levels of visfatin and chemerin in obese women with type 2 diabetes.
Methods: In this study, 30 overweight women with the age range of 45-60 years old were selected and ther were divided into the control group (n = 15), and the experimental group (n = 15) which had no significant differences based on the body fat percentage and the body mass index. Exercise program consisted of increasing aerobic exercise three times were for 12 weeks. To measure Chemerin and Visfatin, blood samples before and 24 hours after the last training session were collected. Data evaluation was performed using ANCOVA to compare the pre-test and post-test in each group.
Results: According to the obtained results, there was no significant difference between weight, body mass index, lean body weight, fat mass and fat percentage, but the chemerin levels have been increased significantly (p=0.0001) and also visfatin and glucose levels have been decreased (respectively p=0.0001 and p=0.001).
Conclusion: Aerobic activities are a stimulating factor for increasing in the chemerin hormone and also a stimulating factor for decreasing in the Visfatin hormone. It could be said that regular aerobic activities in 12 weeks are a good stimulating factor for creating changes in these hormones in women with diabetes and it is probably one of the contributing factors of physiologic changes resulted from these exercise activities is changes in these hormones.
A Azamian Jazi, R Shokouhi,
Volume 24, Issue 8 (11-2016)
Abstract
Introduction: The basic levels of oxidative stress and lipid peroxidation is higher than normal in patients with type 2 diabetes. Therefore, due to the positive effects of exercise training (especially combined exercise training) on oxidative stress and lipid peroxidation in healthy people, the purpose of this study was to investigate the effect of an 8 week combined exercise training (Aerobic and Resistance) on oxidative stress and lipid peroxidation in postmenopausal women with type 2 diabetes.
Methods: In this semi-experimental study, 27 postmenopausal women with type 2 diabetes (age 55.30±4.1
years old, BMI 26.47±3.08 kg/m2) from Yazd city were purposefully selected and randomly divided into experimental (n=13) and control (n=14) groups. The experimental group participated in an eight week combined exercise training (three session per week), but during this period, the control group did not participate in any exercise training program. Superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), fasting blood sugar (FBS) and body fat percent were measured before and after the eight-week combined exercise training. Data were analyzed using paired and independent t-test. Statistical significance was set at P < 0.05.
Results: Serum SOD and CAT levels significantly increased (p = 0.000 and p = 0.001 respectively) and the MDA levels decreased (P = 0.036) in the experimental group after 8 weeks of combined exercise training. Also, FBS (P=0.000) and body fat percent (P=0.005) decreased in the experimental group compared with the control group.
Conclusions: It seems that oxidative stress and lipid peroxidation status in postmenopausal women with type 2 diabetes in the experimental group improve after eight weeks of combined exercise training, compared with the control group.
N Erfani Majd, A Shahriari, Mr Tabandeh, Z Soleymani,
Volume 24, Issue 9 (12-2016)
Abstract
Introduction: Type 2 diabete is a kind of metabolic disease that it is associated with hyperglycemia, hyperlipidemia and disturbed liver function. The aim of the present study was to evaluate the protective effects of Okra Powder on liver damage in high fat diet fed / streptozotocin (HFD-STZ)-induced type 2 diabetic rats.
Methods: In this experimental study, 25 Wistar Albino female rats with an average weight of (200–220 g) were randomly divided into 5 groups: Group I: (control group) rats were fed the standard diet, Group II: healthy rats that received Okra Powder (200 mg/kg) for 4 weeks; Group III (HFD/STZ group): Rats were fed with high-fat diet (HFD) (60% fat) for 4 weeks and then injected low dose of STZ (35 mg/kg), Group IV: Diabetic rats that received Okra Powder (200 mg/kg) for 4 weeks. GroupV: Diabetic rats that received metformin (200 mg/kg) for 4 weeks. At the end of experiment, biochemical parameters were measured. Liver samples were removed and 5-6 µ sections were made and stained by H&E and Sudan black staining.
Results: The results showed that all the biochemical parameters, except HDL-C and serum insulin were increased in diabetic rats, while they were decreased in Okra supplementation group compared to diabetic rats (p<0.05). The liver structure alterations were improved in treated diabetic rats with Okra Powder and metformin.
Conclusion: Our findings confirmed the potential anti-hyperglycemic and hypolipidemic effects of Okra Powder. Thus, it seems it has an important role in the management of type 2 diabete.
Mojtaba Eizadi, Rahman Soory, Aliasghar Ravasi, Kazem Baesy, Sirous Choobineh,
Volume 24, Issue 12 (3-2017)
Abstract
Introduction: Both environmental and genetic factors have been implicated in the development of type 2 diabetes (T2D). The objectives of the present study were: 1) to investigate the effect of high intensity interval training (HIIT) on fasting glucose, insulin and TCF7L2 expression in pancreas tissue of T2D rats, 2) to determine the relation between TCF7L2 expression with insulin changes in the HIIT and control groups.
Methods: In the present applied-experimental study, T2D male Wistar rats induced by intraperitoneal streptozotocin-nicotinamide were assigned to control (no-training) and HIIT (5 times/week/12-week) groups. Fasting glucose, serum insulin and TCF7L2 expression in pancreas tissues of both groups were measured after lasted exercise and compared between 2 groups by independent T test. Also, the relation between TCF7L2 expression and insulin of HIIT to the control group was assessed by Pearson correlations.
Results: The HIIT training in the training group was associated with improved fasting glucose compared with the control group (P<0.001). A significant increase was observed in serum insulin levels (P< 0.001). Also, there was seen a significant decrease in TCF7L2 expression in pancreas tissues in HIIT group compared with the control group (P= 0.038). Significant negative correlation was found between TCF7L2 expression and insulin changes of the HIIT to control groups (r=0.84, P=0.034).
conclusion: HIIT training is associated with improvements in glycemic control and insulin secretion in T2D rats. Based on these data, this improvement can be attributed to decrease in TCF7L2 expression at pancreas tissues by HIIT training.
Ali Akbar Vaezi, Bahare Fallah, Zahra Moshtagh Eshgh ,
Volume 25, Issue 10 (1-2018)
Abstract
Introduction: Basic conditioning factors can influence the self-care behaviors, and it is necessary to perform self-care behaviors in order to prevent diabetes complications and improve the quality of life. This study aimed to investigate the effects of basic conditioning factors on self-care behaviors of the patients with type 2 diabetes who referred to Yazd Research Center.
Methods: In this descriptive-analytical study, 95 patients with type 2 diabetes, systematically selected, were investigated. A questionnaire developed by the researcher, including 25 tests of which the reliability and validity were ascertained, was used in this study. The data were analyzed using SPSS (16), through conducting independent t-test, one way ANOVA and Pearson Correlation Coefficient.
Results: The mean for self-care behaviors of the patients with diabetes was 6/53
+7/11. The results indicated that the lowest scores of the patients' self-care were gotten in blood sugar testing and physical activity, as well as the highest scores were gotten in foot care and nutrition parts. There was a statistically significant difference in the mean scores of self-care of the patients with different gender, age, adequacy of income and employment, educational status, complication arising and other chronic diseases, as well as the duration of the disease (p < 0/05).
Conclusion: In order to promote self-care behaviors, the effectiveness of the demographic factors such as age, gender, educational status, adequacy of income and employment should be considered. The health care centers also should give the patients some essential information about basic conditioning factors.
Ebrahim Banitalebi, Majid Mardaniyan Ghahfarrokhi, Mohammad Faramarzi, Samira Nasiri,
Volume 26, Issue 3 (6-2018)
Abstract
Introduction: Fatty liver is a condition in people with type 2 diabetes mellitus (T2DM). The purpose of this study is to examine the effects of combined training on novel hepatic steatosis indices (fatty liver index (FLI), accumulation product (LAP), hepatic steatosis index (HSI), and Framingham steatosis index (FSI)) in women with type 2 diabetes.
Methods: 35 female with type 2 diabetes were assigned to combined training (n = 17) and control (n = 18). Intervention consisted of combined (aerobic-strength training) for 10 weeks. Data were analyzed using dependent t test to compare pretest and posttest in each group. The Analysis of covariance (ANCOVA) was used to compare the amount of changes in experimental and control training groups after 10 weeks.
Results: The results of the analysis of covariance showed that 10 weeks of combined training caused a non-significant decrease in HSI (P = 0.596), FSI (P = 0.312), FLI (P = 0.327) and a significant decrease in LAP (P = 0.334) compared to the control group.
Conclusion: The results show that 10-week combined training results in a significant decrease in LAP index and a non-significant reduction in FSI, HSI, and FLI indices of women with type 2 diabetes. Therefore, combined training recommended for improve the fatty liver in women with type 2 diabetes.
