Showing 8 results for Stroke
R Fallah, A Shajari, N Tabkhi,
Volume 16, Issue 5 (1-2009)
Abstract
Stroke, though rare in children is among the top 10 causes of death in childhood. Incidence of ischemic and hemorrhagic stroke is the same in children .We report a case of hemorrhagic stroke in a two year old girl who presented with a limp, inability to stand on the left leg and left hemiparesia. Her complaint began 10 days ago after a bout of left clonic seizure. She had been admitted to the hospital for a week due to delayed hemorrhage of the umbilical stump at the age of 18 days. Brain CT scan showed a round, hyper dense area with mass effect in the right supraparietal region. Craniotomy revealed a hemorrhage and report of pathology was hematoma. Considering the delayed umbilical cord bleeding and normality of usual tests for hemostasis and partial deficiency of factor XIII in both parents, the problem was diagnosed as homozygote severe deficiency of factor XIII.
B Farzinrad, K Maghsoodi, K Malakooti,
Volume 17, Issue 2 (7-2009)
Abstract
Introduction: Cerebrovascular disorders are the third leading cause of death in individuals over the age of 50 mental disorders of this origin are reported in up to 50 and even 78 percent of patients. The global goal of this study was to assess mental disorders of stroke patients.
Methods: In a cross-sectional study, 100 consecutive stroke patients in the neurology clinic of Rasool hospital were evaluated by accidental sampling and use of Neuropsychotic Inventory (NPI). Data was analyzed using Chi square and t-test.
Results: 37 men and 63 women with mean age of 62.5 years were assessed over 1 to 12 months after their stroke. The results of Chi square suggested men patients had higher frequency in subscales of delusion, aphaty, disinhibition and sleep disorders and women patients in subscale of anxiety. The results of t-test reported that there was a correlation between right hemisphere lesions and euphory.
Conclusion: Depression, anxiety and aggression were the most common mental disorders after stroke, respectively.
K Ghandehari, F Saboor Davoudian, P Maarufi,
Volume 18, Issue 2 (5-2010)
Abstract
Introduction: Clinical findings affecting disability in stroke patients are important as presence of these factors determines the prognosis and future course of these patients.
Methods: Consecutive stroke patients admitted at Ghaem hospital, Mashhad were enrolled in this prospective study in 2008. Hemihyposthesia, hemianesthesia, hemineglect and homonymous hemianopsia was evaluated in these patients. Disability score was based on the Modified Ranking Disability Score (MRDS), 72 hours post stroke. Mean of MRDS was analyzed by T test and Fisher tests and p<0.05 was considered as significant.
Results: A total of 329 stroke patients were investigated. Hemihyposthesia, hemianesthesia, hemineglect and homonymous hemianopsia was found in 37.4%, 13.8%, 7.9% and 7.3% of the patients, respectively. MRDS was significantly higher in patients with hemianesthesia as compared to other stroke patients, (p<0.001). MRDS of patients with hemihypoestheisa, hemineglect and homonyous hemianopsia was not significantly different than patients without these abnormalities (p=0.44, p=023 and p=0.83). Patients with triad of hemianesthesia, hemineglect and homonymous hemianopsia had significantly higher MRDS than others (p<0.001).
Conclusion: Hemianesthesia is a clinical factor affecting sensory disability in cerebral stroke patients. Presence of the above triad could increase MRDS in these patients.
M Ashrafi, H Montazer Lotfe Elahi , M Dehghani,
Volume 19, Issue 4 (10-2011)
Abstract
Introduction: Stroke is a clinical diagnosis which brings up cerebrovascular diseases. Stroke includes any cerebrovascular accident which leads to local neural defect and lasts more than 24 hours. Stroke has severe and irreversible complications and high rates of recurrence after first episode, therefore we decided to study clinical and paraclinical findings of this disease for better diagnosis and prevention of it.
Methods: We prepared a case series study to review medical files of the patients admitted to pediatric medical center with the diagnosis of CVA between 1993 and 2003. 19 patients were assessed in this study.
Results: Their mean age was 5.72 (SD=3.801). Among clinical signs hemiparesis was the most common finding (89.5%). Vital signs were normal except for two patients with low-grade fever or hypertension. Such cardiac diseases as cardiomyopathy, valvular disorder, d-TGA, and congestive heart failure were common predisposing factors. According to CT scan reports, 6 patients (31.6%) suffered from deep ischemic stroke, and 5 (21.3%), and 2 patients (10.5%) suffered from superficial ischemic stroke and and hemorrhagic stroke, respectively. 2 patients manifested signs of both superficial and deep ischemic stroke. One of them suffered from Moyamoys syndrome and the other was a known case of MELAS (mitochondrial encepholomyopaty lactic acidosis syndrome). CBC was the most important abnormal test.
Conclusion: According to this study, congenital heart diseases are the most common cause of stroke in children. Stroke in children is not frequently associated with vital signs change, and deep ischemic stroke is the most common type of the stroke in children.
K Ghandehari, F Behdani, Z Izadi Mood, M Davarri Edalatpanah, S Asaadi, E Kiadarbandsari, Mm Amjadi, Mr Sobhani,
Volume 23, Issue 6 (9-2015)
Abstract
Introduction:Determining the effect of stress on strock in benficial. If there is a relationship between them, using public education can lead to decrease the risk of stroke. This study investigate the effect of stress on cerebrovascular accident.
Methods: This study was a prospective case-control, which was performed on the patients with stroke referred to nerve clinical Ghaem Hospital, and the control group were selected among the staff of the university with no history of stroke during winter 2015. The persian translation of questionnaire of Holmes and Rahe stress scale related to the last month was completed among all of the participants in both groups. Diagnosis of stroke and determination of its etiology was made by neurologist.
Results: By considering the frequency of serve stress, 361 patients with stroke were investigated and from these 190 patients were in the control group. The relative frequency of stress and stroke and intracerebral homorrhage and subarachnoid hemorrhage were meaningful(p<0.001, p<0.001, p=0.006). There was no significant relationship between the relative frequency of serve stress among the patients with ischemic stroke, cryptogenic infraction, and cardioembolic with atherosclerotic and the control group
(p=0.637, p=0.311, p=0.439, p=0.109,). There were a significant relationship between serve stress and atherosclerotic stroke(p=0.026). While, high stress score was significantly more frequent in atherothrombotic subtype of brain infarction than controls, p=0.046.
Conclusion: There was a meaningful relationship between stress as an important risk factor in the patients with hemorrhagic stroke and atherothrombotic brain infarction. Based on this research stress could be considered as a risk factor of stroke.
Z Zolfkhani , M Rahnema ,
Volume 24, Issue 5 (8-2016)
Abstract
Introduction: After cardiovascular disease and cancer, stroke is the third most common cause of death in the most industrialized countries. The aim of study was assessment of relationship between the effect of Boswelliaserrata aqueous extracts infarct volume in rat stroke model.
Methods: Five groups, each consisting of 7 male wistar rats, were studied. The groups consisting of control, sham and three treatment groups received aqueous extracts Boswelliaserrata for 30 days (50,100 and 150mg/kg day, respectively). The control group received distilled water, while in ischemia induction and sham group they did not receive distrill water. Two hours after the last gavaged dose, overly group with 7 pieces operated for measurement of amount of infarct volume and neurologic deficits. (Middle Cerebral Artery Occlusion Model). The data were analyzed via ANOVA test.
Results: In comparison to the ischemia group, pre- treatment aqueous extracts Boswelliaserrata with the doses of 100 and 150 mg/kg body weight indicated a meaningful difference. In addition, median score of neurological violation was significantly reduced through aqueous extracts Boswelliaserrata consumption in the doses of 100 and 150 mg/kg body weight, compared to the ischemia group.
Conclusion:According to this study, aqueous extracts of Boswelliaserrata can reduce the amount of tissue damage caused by stroke and neurological protection.
Fatemeh Ezoddini-Ardakani, Farnoosh Dehghan , Khalil Sarikhani Khorrami ,
Volume 25, Issue 12 (3-2018)
Abstract
Introduction: The identification of people with carotid calcified atheroma is an important measure to reduce the incidence of brain stroke. The aim of this study was to evaluate the frequency of carotid artery atheroma in post-menopausal women in panoramic radiographs.
Methods: In this descriptive cross-sectional study, 151 panoramic radiographs from women aged 45 years and above that referred to the Radiology Department of Yazd Dental School during 2016-17, were selected by convenience sampling method. Radiographs were examined by PlanMeca 2002 EC proline panoramic digital machine. In radiographs, the presence or absence of carotid calcified atheroma was investigated and cases with differential diagnosis of atheroma were excluded. Patient's tomography data were recorded in a questionnaire and the collected data were analyzed by SPSS20 software and Chi-square test.
Resultus: In this study, 151 panoramic radiographs evaluated, 69 samples (45.7%) had carotid artery atheroma in radiography, and the largest view 40 samples (26.5%) were bilaterally.
Conclusion: The more time passes from the menopause of patients,the more they become involved with carotid artery calcification. That means carotid atheroma has a significant relationship with the number of years pass from menopause.
Mohammad Reza Rahmani, Mohammad Allahtavakoli,
Volume 28, Issue 2 (6-2020)
Abstract
Introduction: Currently, there is no effective and comprehensive treatment for ischemic stroke. There is strong clinical evidence for the benefits of hypothermia in neuroprotection. Therefore, the present study aimed to determine the effect of mild non-invasive hypothermia by JZL-184 on behavioral improvement in stroke rats.
Methods: This study was performed on 5 groups of male mice weighing 25-30 g. The groups were as follows: 1- Healthy group 2- Control group (Stroke) 3- Stroke + DMSO solvent 4- Stroke + Aspirin (40mg /kg) 5- Stroke + JZL-184 (16mg / kg) (n = 8 per group). The drugs were injected intraperitoneally immediately after the stroke. At the times before (time zero) and at 5, 24 and 48 h after stroke induction, body temperature, behavioral testing, including muscle strength and sensory-motor dysfunction were measured. Data were analyzed by SPSS version 18 software and Two-way ANOVA test (P ≤ 0.05).
Results: JZL-184 decreased body temperature at 5, 24 and 48 hours compared to intact and control groups (p <0.001). Injection JZL-184 and Aspirin improved muscle strength and sensory-motor function (p <0.001) compared to the control group. Aspirin also improved behavioral tests compared to the control group (p <0.01), but did not show any effect on the body temperature compared to the intact group at time 48. Only in JZL-184 group, the behavioral tests score was similar to the intact group at the 48 h after stroke.
Conclusion: JZL-184 may have been able to improve neuronal function by hypothermia induced by the agonist effects of cannabinoid receptor 1 (CB1), thereby improving muscle strength and sensory-motor function after cerebral ischemia.
