Showing 2 results for Reference Values
M Akhondi-Meybodi , M Askarzadeh, N Bashardoost, M Amir-Baygi,
Volume 18, Issue 4 (9-2010)
Abstract
Introduction: Alanine aminotransferase (ALT) is the most useful laboratory marker of hepatic necroinflammation that is used for diagnosis of liver diseases. Based on recent data, the investigators suggested a new upper limit of normal, which was based on patient's sex and BMI criteria. This prospective study was done to determine the normal range of serum alanine aminotransferase (ALT) in healthy normal population of Yazd from October 2008 to June 2009.
Methods: In this study, 565 randomly selected apparently healthy people without any defined diseases were selected .Cases who had any history of hepatic diseases, history of hepatotoxic drugs or alcohol were excluded. Patients positive for HBsAg or HCV were also excluded. ALT measurements were performed by the the same laboratory method using Pars Azmon kit made in Iran. Healthy ranges for ALT levels were computed. Univariate and multivariate analyses were performed to evaluate associations between clinical factors and ALT levels.
Results: The 95Th percentile of ALT was 35.6 I.U for males and 31.2 IU for females and the mean ALT was 23.03±9.93 IU/dL. In this study, ALT levels were related to gender, age, BMI, FBS and cholesterol, but there was no relation with triglyceride levels. (Age, r=-0.100, BMI .r=0.13 FBS r=0.119, cholesterol r=0.142.)
Conclusion: The 95Th percentile of ALT was, 35.6 IU/dL for males and 31.2 IU/dL for females. Serum ALT is related to gender, BMI, FBS, cholesterol but is not related to triglyceride levels .ALT is inversely related to age.
Hosein Fallahzadeh, Abdollah Javanrashid, Habibollah Esmaily, Omid Kiani, Masoud Mirzaei,
Volume 25, Issue 12 (3-2018)
Abstract
Introduction: The reference values for anthropometrics obtained from a specific population may not be appropriate for use in other populations. This study aimed to provide the reference values for body mass index (BMI) in a large Iranian population aged 20-69 years old living in Yazd City, Iran.
Methods: In this study, anthropometrics and related variables of 9422 residents of Yazd were analyzed. Body mass index (BMI) for the 5th, 85th, 90th, and 95th percentiles according to gender and age were calculated. The generalised additive models for location, scale and shape (GAMLSS) was fitted to the data. Akaike's Information Criteria (AIC) was used to study the occasion of the model. The R software was used to analyze the data.
Results: Overweight levels for healthy men and women varied from 25.2 to 28.4 and 25.6 to 27.9, respectively. The levels of obesity varied from 27.8 to 30.3 in men and from 28.2 to 32.3 in women. According to the suggested cut offs, the prevalence of obesity was 27.9% , the prevalence of overweight was 17.1% and the overall prevalence of obesity and overweight was 45% in the reference population.
Conclusion: The findings of this study showed that the need for more attention to obesity and overweight and lifestyle improvements in weight loss, especially in females, are completely felt and the causes of this phenomenon and its harmful effects on the health of the community should be more prominent in the policy makers of the health sector
