Showing 5 results for Recurrence
S Inaloo, M Ghofrani,
Volume 13, Issue 4 (10-2005)
Abstract
Introduction: This study was aimed to asses the rate of recurrence after the first unprovoked seizure in
children.
Methods and Materials: In a prospective study, we recruited 145 children who presented with primary
unprovoked seizure and were followed for at least 12 months after the first seizure.
Results: Seventy five children (51.7%) experienced subsequent seizures. The cumulative risk of seizure
recurrence following the first seizure was 16.5%, 35%, 47% and 51.7% at 1, 6, 12, 24 months, respectively.
The median time for repeated seizure was 5.4 months with 67% of recurrences occurring within the initial 6
months, 92% within 1 year and 100% before the end of two years. On multivariable analysis, risk factors for
resumption of seizure comprised of abnormal electroencephalography (EEG) and age greater than ten years
at the time of occurrence of the first seizure. On unvariable analysis, etiology of seizure, history of neonatal
problems and lack of AED (Antiepileptic drugs) usage increased risk of recurrence.
Conclusion: This study revealed that the risk of seizure recurrence in our patients was relatively high. Those
with abnormal electroencephalography and age greater than ten years at the time of occurrence of the first
seizure were at greater risk for recurrence of seizures.
S Akhavan Karbasi , R Fallah, M Sadr- Bafghi , M Golestan, Z Eslami, N Owaisi,
Volume 15, Issue 3 (12-2007)
Abstract
Introduction: Seizure is the most common pediatric neurology problem that occurs in 10% of children. The purpose of this study was to determine the recurrence rate of seizures after one year and its relationship with paraclinical findings of the first attack.
Methods : In a historical cohort analytic study , 131 children with first seizure admitted to Shaheed Sadoughi Hospital between March 2004 to August 2005 were evaluated for recurrence rate during one year and its relationship with serum levels of sodium, potassium , glucose, calcium , Hb , MCV and PMN during the first attack.
Results: 79.4% of cases were in febrile seizure group and 20.6% in first unprovoked seizure group (FUS).Of the total, 27.84 % of patients had seizure recurrence ( 27.9% in febrile and 25.9% in afebrile group). Mean survival recurrence rate was 10.11±0.32 SD months (10.25±0.33 SD months in febrile group and 9.57±0.83 SD months in FUS). Survival analysis showed that seizures recurred later in older patients. Younger age and lower Hb levels in the febrile seizure group and lower MCV in the FUS group were associated with an increased risk of recurrence.
Conclusion: In this study, anemia and microcytic RBC were risk factors for seizure recurrence. Therefore, more studies should be done so as to decrease seizure recurrence by treating and preventing anemia.
M Motovali-Bashi, F Kouhkan, Z Hojati,
Volume 16, Issue 4 (1-2009)
Abstract
Introduction: Insertion or deletion of a guanine in -1607 at promoter region of matrix metalloproteinase-1 enzyme creates two allelic types for this gene in the population: 2G and 1G, respectively. 2G allele contains an extra binding site for ETS transcription factors that this may increase the level of gene expression. Therefore, aim of this study was investigation of the single Guanine insertion in the promoter gene and its association with colorectal cancer patient survival rate and tumor progression.
Methods: Blood samples from 150 colorectal patients and 100 cases were extracted. The mean follow-up was 25 months (12-36 months). Cases and patients were genotyped using genomic DNA extraction and PCR-RFLP.
Results: Colorectal cancer patients were divided in two groups with activity of metastasis (M+) and without activity of metastasis (M-). 2G allele in metastasis group (55%) showed more frequency rather than controls (23%). Survival analyses showed that 3 years survival patients rate in the patients without metastasis activity carrying 1G allele (homo and heterozygote) was 81% and for 2G homozygote is 66% (p=0.04). The survival rate dependent to cancer was 90% and 71%, respectively (P=0.01).
Conclusion: According to the results, it seems that patients carrying 1G allele show a better survival rate dependent on cancer as compared to patients who do not carry this allele.
Sajjad Saadat, Mozaffar Hosseininezhad,
Volume 29, Issue 7 (10-2021)
Abstract
Introduction: The aim of this study was to compare eating behaviors in the patients with multiple sclerosis (MS) with recurrence of the disease in the past year and the control group.
Methods: This analytical cross-sectional study was a comparison that was performed in the statistical population of two groups of people with MS in Guilan Province in the second half of 2018. The first group consisted of people with MS with a recurrence of the disease in the past year and the second group of people with MS without a history of recurrence of the disease in the past year that were selected by matching the variables of age, sex and duration of the disease. In each of these groups, 104 people were employed as a sample in a targeted method from medical centers in Rasht. In order to collect data demographic information form and Dutch Eating Behaviour Questionnaire were used. Research data were analyzed by independent t-test using SPSS software version 16.
Results: The results showed that among patients with MS with a history of recurrence and the control group there was a significant difference (P <0.05) in the variables of emotional eating (t = 3.03, P = 0.01), external stimuli (t=4.49, P=0.01) and inhibition in eating (t =3.81, P=0.01).
Conclusion: Inappropriate eating behaviors are one of the factors associated with recurrence and disease attacks in people with MS. Therefore, it is suggested that psychologists and nutritionists consider the role of eating behaviors in these individuals to reduce disease attacks.
Hamid Hoboubati, Masoud Khoshbin, Hossein Fallahzadeh, Moein Nemati, Gholamhossein Halvani, Rohollah Fallah Madvari, Shoukoh Mirjalili,
Volume 30, Issue 3 (6-2022)
Abstract
Introduction: Meningioma is a benign tumor of the brain, which shows a good response to treatment, surgery and benign pathology, but there is a possibility of recurrence. Therefore, the present study was conducted to investigate the relationship between recurrent meningioma risk factors and the rate of meningioma recurrence in Yazd City.
Methods: This descriptive-analytical study was performed on all the patients who have surgery for meningioma in Shahid Rahnemoun and Mortaz Hospitals in Yazd City for 10 years. Patient's information, including age, sex, size, grade, diseases and bone changes were extracted from the patients' records. After determining the recurrence status of the disease, information was entered into SPSS version 16 software for Chi-square, Anova and T-test.
Results: The most common meningioma was in the age group of 50 to 70 years. In this study, out of 300 patients with meningioma who underwent surgery, 50 (16.7%) had a recurrence of the disease. The recurrence rate was significantly associated with meningioma size, disease grade, and radiotherapy and diabetes (P <0.05). The recurrence rate in this study decreased with the increasing age of the patients.
Conclusion: According to the results, considering factors such as age, disease grade, tumor size, radiotherapy and diabetes, which are important predictors of disease recurrence, in managing meningioma patients after surgery and identifying high-risk individuals for disease recurrence are helpful. In the following, due to the involvement of effective factors in the disease, more extensive and retrospective studies are recommended.
