Introduction: Prevalence of cardiovascular diseases is rooted in inflammation and inflammation is along with the increase of ICAM-1. The aim of the present study was to review the effect of combination of high interval training and flaxseed oil supplementation on plasma concentration of ICAM-1 of rats.
Methods: In this experimental study, 30 rats were selected and divided into six groups of five male rats, including (1) control, (2) training, (3) 10 mg/kg Flaxseed oil, (4) 30 mg/kg Flaxseed oil, (5) training with 10 mg/kg Flaxseed oil and (6) training with 30 mg/kg Flaxseed oil. Groups of 2, 5 and 6 were trained with high intensity interval training for 10 weeks and five sessions per week, also groups 3 to 6 received flaxseed oil for 10 weeks. For statistical analysis of data two way ANOVA test was used (p≤0.05).
Results: 10 weeks treating high intensity interval training for 10 weeks had significant effect on the increase of the plasma concentration of ICAM-1 of male rats (p=0.001). Nevertheless, Taking 10 weeks 10 and 30 mg/kg flaxseed oil supplementation for 10 weeks has significant effect on reducing the plasma concentration of ICAM-1 of rats (p=0.001). Training and taking flaxseed oil supplementation have interactional effect on reduingc the plasma concentration of ICAM-1 of male rats (p=0.001).
Conclusion: Combination of high intensity interval training and flaxseed oil supplementation has interactional effects on the improvement of plasma concentration of ICAM-1 in male rats.
