Showing 3 results for Dermatitis
R Fallah ,
Volume 13, Issue 3 (7-2005)
Abstract
Biotin is a water-soluble vitamin and co-factor for activation of carboxylases apoenzymes. Biotinidase enzyme is essential for release of biotin from apoenzymes. Absence of biotinidase is an autosomal recessive trait with a prevalence of 1 in 60000. Clinical manifestations of biotinidase deficiency include dermatitis, alopecia, seizures, hypotonia, developmental delay, hearing loss, visual impairment and immunodeficiency. With early diagnosis and treatment with biotin supplements, it is possible to prevent clinical manifestations and neurological deficits.
We report a case of biotinidase deficiency with seizures, developmental delay, acrodermatitis enthropathica manifestations and mild compensated acidosis.
Z Moosavi, D Samadzadeh,
Volume 14, Issue 3 (10-2006)
Abstract
Introduction: Atopic dermatitis (AD) is a multifactorial chronic and inflammatory disease present all over the world. Only a few epidemiologic studies on AD have been carried out in the eastern world, while most of the published papers belong to western countries. To determine prevalence of AD in 7-11 year-old school children in Ahwaz as there has been no previous study in this region.
Methods: In this descriptive study, 2500 children aged between 7 and11 years (1250 boy and 1250 girls) were examined on the basis of Hanifin and Radjka criteria. Collected data was analyzed to detect frequency of AD on the basis of Radjka and Hanifin major and minor criteria.
Results: Of the total, 3.9% suffered from atopic dermatitis (4.3%girls and 3.4%boys) and all of them had major criteria, itching and chronic recurrent dermatitis.
Conclusion: Considering the prevalence of AD in children of Ahwaz, it is proposed that programs and measures for reduction of external aggravating factors and similarly, education of the patient’s families can reduce the complications and improve the quality of life in these children.
Abbas Khalili,
Volume 32, Issue 1 (4-2024)
Abstract
Introduction: Inborn error of immunity (IEI) includes variety of genetic disorders that affect both the innate and acquired immune system. The number of primary immune deficiency disorders is increasing due to advanced laboratory testing methods. The patients with IEI are susceptible to multiple infectious and non-infectious diseases، including autoimmune disorders، allergies، and malignancies. Several studies have shown an increasing prevalence of non-infectious disorders in patients in IEI. Among the non-infectious manifestations of primary immunodeficiency، allergic symptoms can play an effective and important role in diagnosis and treatment of these patients.Articles were searched in Google Scholar، PubMed، Web of Science، and Scopus databases. In this review، we have tried to use the latest and most reliable articles related to the subject that have been published in Persian and English language.
Conclusion: Allergic diseases can be a common part of some primary immunodeficiency diseases. Even in some types of primary immunodeficiency، they are considered the main symptom and important indicator of the disease، which are very decisive factors for the diagnosis of immunodeficiency.
