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Showing 7 results for Cardiovascular Disease

A Rashidlamir, A Saadatnia,
Volume 19, Issue 2 (6-2011)
Abstract

Introduction: The cause of many metabolic diseases is a progressive increase in fasting insulin levels that is generally associated with inflammatory status. In such conditions, circulating resistin hormonal levels and CRP levels also increase. The aim of the present study was to determine the effect of 2 months aerobic training on insulin resistance and inflammatory markers. Methods: In the study, 30 middle aged healthy men volunteered (Age=38.56±4.77, BMI=25.14±2.16) to participate and based on their body fat percentage were assigned in two equal groups. Experimental group was asked to perform 2 months of aerobic exercise, 4 sessions a week with 60-80% maximum heart rate, while the control group was sedentary during the same period. Blood samples were collected 48 hours before the first session and 48 hours after the last session under similar conditions. Results: Plasma insulin (p≤0.001) and glucose (p≤0.001) levels decreased and consequently insulin resistance index also decreased (p≤0.001) in the experimental group as compared to controls. Also, resistin concentrations increased (p≤0.001), while CRP concentrations decreased (p≤0.001), respectively in the experimental group. Conclusion: In general, it can be concluded that regular aerobic exercise due to improved insulin resistance and plasma levels of two inflammatory markers (CRP and the resistin) reduces risk factors of metabolic disease and atherosclerosis and can be used as an effective strategy to prevent such diseases.
F Mohammadi, M Veissi, F Haidari, H Shahbazian, M Mohammad Shahi,
Volume 22, Issue 6 (2-2015)
Abstract

Introduction: Cardiovascular disease is more prevalent in patients with type 2 diabetes. Regarding the role of probiotics in control of inflammation and modulating the lipid profile, this study assess the effect of probiotic and conventional yogurt on inflammatory markers and lipid profile in type 2 diabetic patients. Methods: Forty- four subjects with type 2 diabetes were randomly assigned to two intervention and control groups. The intervention group consumed 300 g/d probiotic yogurt (enriched with Lactobacillus acidophilus La-5 and Bifidobacterium lactis Bb-12) and the other consumed 300g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intakes, inflammatory markers and lipid profile were evaluated before and at the end of intervention. Results: The consumption of probiotic yogurt significantly decrease in glycosylated hemoglobin (HbA1c,p=0.032). Also, TNF-α levels and atherogenic indices (LDL-c / HDL-c) reduced in intervention group at the end of the study (p=0.040 and P= 0.002, respectively). There was a significant increase in HDL-c in probiotic group (p=0.007). No significant changes were observed in biochemical parameters in conventional yogurt (P> 0.05 ). Conclusion: Consumption of probiotic yogurt improved lipid profile and some inflammatory biomarkers in patients with type 2 diabetes. Also, probiotic yogurt caused significant decrease in HbA1c. It is suggested that probiotic yogurt may be used as an adjunct therapy to reduce the cardiovascular disease risk factors in type 2 diabetes mellitus patients
Masoud Mohammadi , Masoud Mirzaei ,
Volume 25, Issue 8 (11-2017)
Abstract

Introduction: Effective policies to reduce non-communicable diseases, particularly cardiovascular diseases can be achieved using reliable evidence. Considering the importance and high cost of cardiovascular diseases, the present study was conducted to determine the population attributable fraction of cardiovascular disease associated with diabetes mellitus in the Yazd city
Methods: This study used the epidemiological data on prevalence of diabetes mellitus from Yazd Health Study (YaHS), which was conducted from 2013 to 2014 in Yazd Greater Area. Measurement  of  the association (relative risk) between diabetes and cardiovascular diseases was adopted from Tehran Lipid and Glucose Study. Population attributable fraction was calculated using these the prevalence and relative risk according to the relevant equation.
Results: Population attributable fraction of cardiovascular disease due to diabetes was more in females )12.3% -%95 CI=10.8-13.6)  compared to males (6.5% -95% CI=5.6-7.4)  ) . In other words, up to 6.5% of cardiovascular diseases in males and 12.3% of it in female can be prevented by reducing the prevalence of diabetes in Yazd population.
Conclusion: Population attributable fraction of cardiovascular disease associated with diabetes is higher in females who live in Yazd city compared to males, thus more health promotion and diabetes’ prevention programs should be introduced to this group. More prevention programs are needed to control diabetes and cardiovascular diseases, consequentially.
Neda Ghazavi, Ebrahim Rahimi, Zahra Esfandiari, Amir Shakarian,
Volume 26, Issue 9 (12-2018)
Abstract

Introdution: The inappropriate nutrition is one of the reasons for non-communicable diseases. Consumption of a variety of sweets with high saturated fatty acids content is associated with an increased risk of cardiovascular disease, non-alcoholic fatty liver, insulin resistance, and so on. This study was conducted with the aim of collecting information on the types and amount of saturated fatty acids in Iranian traditional sweets.
Methods: A total of 369 samples (packed and unpacked) from 23 types of Iranian traditional sweets were randomly purchased from different brands  in Isfahan supermarkets and their saturated fatty acid content was measured by gas chromatography.
Results: The total average of the saturated fatty acid content of all samples was 38.6% in total fat. The highest amount was found in Loz (92.4%) and the lowest content was measured in Nan-khormai and cake Yazdi (less than 20%). Most of the samples (80.5%) had 20-50% of saturated fatty acids. Saturated fatty acids of C16:0, C18:0 and C20:0 were found in all samples and C16:0 had the highest total mean of saturated fatty acid (25.9%). The labeling of some sweet products was associated with reduction in their saturated fatty acid content.
Conclusion: Considering the high level of saturated fatty acids in some types of Iranian high consumption sweets, mandatory labeling of traditional sweets in order to enhance the consumer's awareness of the solid fats content as well as the consumer's awareness of the harmful effects of these fats on the body health can be effective in preventing various diseases, including cardiovascular diseases.
Hanie Elahimehr, Mahnaz Shahgholian, Mohammad Hossein Abdollahi, Fariba Rajabi,
Volume 29, Issue 8 (11-2021)
Abstract

Introduction: Cardiovascular disease is one of the causes of mortality in the world, which psychological factors play an important role in its occurrence and exacerbation. This study aimed to investigate the prediction of emotional repression based on alexithymia and type D personality in cardiovascular patients.
Methods: Participants were 100 patients with coronary artery disease selected through accidental sampling from the patients undergoing treatment at Rajaee Heart Hospital in Karaj City and completed TAS-20, DS14 and ECQ questionnaires. The validity and reliability of all three questionnaires have been confirmed in domestic and foreign studies. Data were analyzed using SPSS version 16 Software and Pearson correlation, Multiple regressions.
Results: The correlation results showed that there was a significant relationship between alexithymia and personality type D with emotional repression in the cardiac patients at the level of 0.05, and the results of multivariate regression results showed that alexityymia and personality type D did not predict emotional repression.
Conclusion: Alexithymia, personality type D, and emotional repression are risk factors for the development and exacerbation of cardiovascular disease.

Elahe Malekyian Fini, Sajad Ahmadizad,
Volume 29, Issue 8 (11-2021)
Abstract

Introduction: The importance and necessity of preventing the occurrence of these diseases in order to maintain and promote health, has attracted the attention of many researchers to methods of preventing the occurrence of cardiovascular injury. Metabolic effects of muscle mass loss due to the natural aging process are caused by decreased muscle activity and lead to high prevalence of obesity, insulin resistance, type 2 diabetes, hyperlipidemia and cardiovascular disease. These risk factors cause disorders in the cardiovascular structure such as myocardial infarction, arterial stiffness and endothelial dysfunction, etc. Research also has shown that muscle strength is inversely related to all causes of death and the prevalence of metabolic syndrome. Therefore, the aim of this study was to provide safe resistance training methods for cardiovascular patients.
Conclusion Resistance exercise is effective in preventing or reversing the functional, morphological and structural changes of the heart. Research shows that resistance training prevents the reduction of skeletal muscle mass and its function. This can also compensate for the functional decline caused by aging and disease. Because the methods of resistance training are various and are associated with many methodological problems, the study of the effect of exercise and resistance training in cardiovascular patients has always been controversial. This article reviews the findings of previous research examining the effects of the interaction between acute exercise and training in cardiovascular patients, and concludes the principles of prescribing resistance training in these patients. Overall, this study suggests that resistance training is beneficial even for the patients with CHF.

Mehdi Basaki,
Volume 33, Issue 1 (4-2025)
Abstract

Introduction: Cardiovascular diseases are responsible for about one-third of deaths worldwide. Consequently, innovative strategies for the development and treatment of cardiovascular diseases are of great interest. Vitamin E is known for its unique and remarkable anti-oxidant and anti-inflammatory properties. The advantages of vitamin E in cardiovascular diseases have been investigated and the relationship between lower vitamin E levels and increased cardiovascular events supports this view. However, clinical trials reveal inconsistent and disappointing results in reducing cardiovascular events with vitamin E supplementation. The analysis of studies shows that in addition to the amount, duration of consumption, the type of vitamin E isoform, and its natural or synthetic source, factors such as genetic polymorphisms and the clinical status of users also affect the impact of vitamin E supplementation on cardiovascular events.
Conclusion: Patients with cardiovascular diseases, as well as those receiving preventive care for cardiovascular events or at risk of bleeding, should take Vitamin E only under medical supervision.  Considering that low concentrations of antioxidants such as alpha-tocopherol can lead to greater susceptibility to diseases related to oxidative stress and inflammation in the population, reviewing or reinterpreting the mechanisms of vitamin E effects in the cardiovascular process is essential for a better understanding of the relationship between Vitamin E and cardiovascular diseases. It is equally important to establish public health initiatives and strategies to encourage the intake of natural vitamin E sources and healthy fats.
 


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