Journal of

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Introduction: ^99mTc–Dimercaptosuccinic Acid (DMSA) as evaluation of pediatric genitourinary abnormalities has an important role in pediatric nuclear medicine. The aim of this study was to estimate organs absorbed dose for children injected by ^99mTc DMSA using MIRDOSE software and hybrid planar/SPECT method.

Methods: After injection of ^99mTc-DMSA, ten children with genitourinary abnormalities underwent 3-5 planar scans and single SPECT scan (at 1 to 20 h post injection). Also for anatomical reference of patients’ organs, MRI scans were performed for each patient. A hybrid planar/SPECT method was used to plot time activity curves for obtain source organs cumulated activity and then to calculate obserbed doses of organs MIRDOSE software was used.

Results: Mean absorbed dose due to ^99mTc-DMSA in pediatric for kidneys (200 ± 160), adrenals (15.1 ± 9.5), urinary bladder wall (14.7 ± 9.8), spleen (12.7 ± 7.8), gonads (12.4 ± 11.2), pancreas (10.5 ± 6.2), gall bladder wall (9.8 ± 5.7) , , , , , micro Sivert per MegaBequrel, respectively. Also, the mean effective doses was 10.01 ± 6.03 µSv/MBq.

Conclusion: The difference between the radiation doses received by the various organs of the patients caused by different amounts of radiopharmaceutical uptake in organs for different patients. Image quantities practical method using planar/SPECT hybrid method can be utilized with acceptable accuracy in determination of cumulative activity.

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Introduction: Bone scan is a nuclear medicine scan test, which leads to finding specific abnormalities in the bone. Methylene Diphosphonate (MDP) is used to bone scan. This combination is absorbed by bone tissue and is excreted by the kidneys and bladder. The purpose of this study was to estimate the absorbed dose of organs in bone scan with injection MDP radiopharmaceutical using Mirdose software and the SPECT/planar hybrid method.
Methods: 20 females who referred to the Nuclear Medicine Department for bone disorders were examined and three planar images intervals of 1, 3 and 5 hours and one SPECT at 3 hours after injection were taken from them. The cumulative activity of the organs was obtained using the SPECT/planar hybrid method and then the absorbed dose was calculated using Mirdose software.
Results: The mean absorbed dose due to ^99mTc-MDP in women for heart wall (0.0026±0.0005), kidneys (0.043± 0.0072), liver (0.0034±0.0001), lungs (0.0024±0.0001), muscle (0.0028±0.0006), ovaries (0.0056±0.0004), spleen (0.0048±0.0003), urinary bladder wall (0.0680±0.0120), bones (0.0046± 0.0006) and reminder of the body (0.0031± 0.00098) mGy/MBq were obtained.
Conclusion: Bladder, kidneys, ovaries, spleen, bones, liver, muscles, walls of the heart and lungs have the highest rates of absorbed dose in organs, respectively.Since the women studied in this study had different diseases and bone disorders and biological characteristics, and some of them were metastatic due to the disease, this led to a different absorption of radiopharmaceuticals in the various organs of these patients, which caused the difference is in the average absorbed dose of radiopharmaceuticals in their organs.
 

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Introduction: Today electrophysiology studies and ablation have been developed due to increasing arrhythmias disorder of heart. In these diagnostic – treatments methods, the use of fluoroscopy can be causes patient radiation dose, therefore evaluation of patient's absorbed dose is necessary to protection of the radiation. The aim of this study was to evaluate the absorbed dose in patients undergoing electrophysiology and cardiac ablation and to estimate their risk of cancer in Yazd Afshar Hospital.
Methods: This study was a cross-sectional study. In this study, the mean absorbed dose of referral patients for electrophysiology studies and ablation had been measured in the cat. Lab of Afshar Hospital, Yazd. The dosimeter had been used in this research was KAP meter, the M4 DIAMENTOR made in Germany that was able to measure dose-area product and time of the fluoroscopy. The patient effective dose was calculated by the PCXMC software from dose-area product.
Results: The mean dose-area in ablation and electrophysiology studies was respectively 153.34±105.32 and 5.62 14.88 Gy.cm² and the radiation time range was recorded 3.32 to 68.65 minutes and 1.03 to 6.28 minutes, respectively. The mean effective dose of ablation and electrophysiology studies were respectively 16.38 and 1.65 mSv. The cancer risk per ten thousands of patients, who were under the ablation and electrophysiology examinations were estimated 13 and 1.3 people, respectively.
Conclusion: Increasing of patient dose due to ablation in this study relation to the other studies can be due to long old of image intensifier device.