Showing 8 results for mahdavi
Mr Shoja, M Mahdavi,
Volume 14, Issue 2 (Summer 2007 2006)
Abstract
Purpose: To report a case of unilateral severe visual loss and bilateral optic disc cupping secondary to brain metastasis of bronchogenic carcinoma
Patient and findings: A 48 year-old woman presented with severe visual loss of left eye without redness or pain or any systemic findings .Clinical findings included decreased visual acuity of left eye to 4 m CF and (+3) positive Marcus-Gunn reflex .There was asymmetric optic disc cupping associated with visual field defect in left eye
The neurologic investigations showed a secondary metastatic tumor in the brain from bronchogenic carcinoma.
Conclusion: Before making a diagnosis of normal -tension glaucoma in asymmetric optic disc cupping and normal intraocular pressure, ophthalmologists should rule out neurologic defects and brain tumors.
J Modaresi, H Mahdavi, R Mahmodi,
Volume 14, Issue 2 (Summer 2007 2006)
Abstract
Introduction: Incomplete anesthesia of inflamed teeth is a well known clinical occurrence and the purpose of this study was to evaluate the effectiveness of Ibuprofen as a premedication in improving the quality of anesthesia in patients with inflamed teeth pulps.
Methods: Forty patients with the diagnosis of irreversible pulpitis in one mandibular tooth were selected. Two other teeth in the same quadrant were selected as controls. Electric pulp tester (EPT) was used in this study to evaluate the quality of anesthesia. The subjects were divided into two groups randomly, and after recording of pulp tester response in each group, one of the two drugs ibuprofen or placebo was administered 1 hour prior to anesthesia injection. After injection, EPT measurement was recorded. The reversed EPT scale was used for evaluation of the depth of anesthesia.
Results : Data was analyzed to statistically compare the results before and after anesthesia and drug administration in cases and control group .Significantly lower TSLs were observed in the ibuprofen group (Pvalue= 0.001).
Conclusion: This study concluded that preoperative administration of ibuprofen (if not contraindicated)
1 hour before local anesthesia injection is an effective method for achieving deep anesthesia during RCT of teeth with irreversible pulpitis.
R Mahdavi, L Nikniaz, B Pourghassem Gargari, J Ghaemmaghami,
Volume 19, Issue 3 (Jul-Aug 2011 2011)
Abstract
Introduction: Taking into account the importance of micronutrients in health and growth of the infants, the concentrations of zinc, copper, and iron in breast milk of mothers belonging to different economic classes and their effects on infants’ growth were investigated.
Methods: Milk samples and information on personal characteristics, anthropometric and 24-hour food recall were collected from 90 lactating women belonging to 3 different socioeconomic classes who had exclusively breastfed their 90-120 day old infants. Concentrations of trace elements were analyzed using atomic absorption spectrophotometry and dietary information of subjects was analyzed by Nutritionist III software program. Statistical tests included Multiple Regression, ANOVA test and Independent t-test.
Results: The mean zinc concentrations in mothers’ breast milk belonging to high, moderate and low socioeconomic groups were 1.6, 1.9 and 2.3 mg/l, respectively. Copper levels were 0.41, 0.47 and 0.85 mg/l, respectively and iron levels were 0.75, 0.8 and 0.9 mg/l, respectively. Group comparisons showed significant differences (P<0.05). Although association between mineral concentrations and WAZ or HAZ of infants was not significant, the WAZ of infants whose mothers' milk zinc concentration was more than 2 mg/l was significantly higher than WAZ of other infants (P<0.03). Despite no significant correlation between trace element intake and trace elements in milk, negative and significant correlations between maternal age and milk minerals concentrations were observed.
Conclusion: The concentration of studied trace elements in milk of mothers with low economic status was higher but was not related to intakes and it was probably related to mothers' age. So, dietary consultations for older lactating mothers are needed.
O Mahdavi, N Boostani, N Gholami,
Volume 20, Issue 3 (Jul-Aug 2012)
Abstract
Chronic sclerosing sialadenitis(also known as Kuttner tumor) is a chronic inflammatory condition of the salivary glands and one of the salivary gland enlargment that was first described by Kuttner in 1896. Unilateral or bilateral involment of the submandibular gland occurs more commonly than any other salivary glands. Few cases of chronic sclerosing sialadenitis in minor salivary glands have been reported. This article presented a case of chronic sclerosing sialadenitis in minor salivary gland of the floor of the mouth.
H Zarinnahad, A Mahmoodzadeh, K Pooshang Bagheri , M Mahdavi, D Shahbazzadeh, A Moradi,
Volume 21, Issue 2 (May-Jun 2013)
Abstract
Introduction: Cervical cancer is the second prevalent cancer in developing countries and the sixth prevalent cancer in USA. Since conventional treatment methods are associated with detrimental side effects, searching for new drugs using natural ingredients is very important. Previous studies have shown that melittin (main component of honey bee venom) has anticancer properties along with the effect on cell membrane and activation of apoptosis. In this study, inhibitory effects of melittin on the viability and proliferation of cervical cancer cell line (HeLa) was investigated.
Methods: Melittin was purified from honeybee venom using reversed-phase HPLC method. Then, biological activity of melittin was examined by hemolytic activity analysis on the red blood cells. In order to investigate whether melittin inhibits proliferation of HeLa cell, MTT assay was performed. HeLa cells were plated in a 96-well plate and treated with serially diluted concentrations of melittin for 12 and 24 hours. The viability of the cells was measured via MTT assay at 540nm.
Results: Melittin showed a strong hemolytic activity (HD50=0.5 µg/ml) which can be reduced by FBS(HD50=2 µg/ml). Results of MTT assay indicated that melittin shows cytotoxic effect on cervical cancer cells with IC50 = 1.2 ug/ml at 12h incubation period.
Conclusion: In this study, biological activity of melittin and inhibitory effect of FBS on hemolysis were determined via hemolytic activity analysis. MTT assay indicated that melittin induced cytotoxic effects in a dose dependent manner on cervical cancer cells and it also revealed dependence on incubation time as well.
F Ahmadi-Motamayel , F Ebrahimi, A Mahdavinezhad,
Volume 23, Issue 9 (Nov-Dec 2015)
Abstract
Introduction: Developmental anomalies of oral mucosa are not necessarily related to a specific disease, that may be demonstrated in differential diagnosis of oral disease and premalignant lesions. Mucosal anomalies incidence may be varied in different individuals, which can be related to many genetic and environmental elements. Therefore, this study aimed to evaluate the developmental anomalies of oral mucosa in the patients referred to department of Oral Medicine of Hamadan Dentistry faculty in 2014.
Methods: In this cross-sectional study, the developmental anomalies of oral mucosa were studied in 800 patients, who referred to Hamadan School of Dentistry in Iran. All the 800 patients were clinically examined using dental mirrors on the dentistry unit in regard with diagnosis of mucosal anomalies. Demographic data and types of mucosal anomalies were recorded in a predesigned questionnaire. In order to analyze the study data, SPSS software (ver, 16) was applied via chi-square test at significance level of 0.05.
Results: Oral developmental lesions were observed in 700 patients (87.5%). The most common lesion was reported as fissured tongue (50.9%), followed by Fordyce granules (49.5%), Macroglossia (17%), torousplatinus (13.4%). A significant association was detected between fissured tongue, macroglosia ,fordice granule with gender and age, Varicosities and furred tongue with age and Torus palatines , Comissural lip pit and hairy tongue with gender .
Conclusion: The findings of the present study revealed high prevalence of oral mucosal anomalies. As a result, dentists and medical practitioners are demanded to attend to the oral mucosal anomalies.
Reyhaneh Mirzaei, Fahimeh Nemati Mansour, Mehdi Mahdavi,
Volume 26, Issue 7 (Oct 2018)
Abstract
Introduction: Hepatitis is a systemic diseasethat causes liver inflammation. The prevention of this infection is a vaccination. The commonly used vaccine to fight this disease is to use the vaccine formulated with Alum. This vaccine cannot provide immune response and complete productivity in some people. In this study, cellular and humoral immune responses of hepatitis B vaccine were compared with hepatitis B vaccine formulated in MF59 adjuvant.
Methods: In this experimental study, Balb/c mice received different formulations of the vaccine subcutaneously three times with a two-week interval. Then, the mice were bled and the levels of anti-HBs Ag were determined by the ELISA method. IFN-γ, IL-4, IL-2 and IFN-γ / IL-4 cytokines were examined by the ELISA method from the soup of spleen cells culture. The data were analyzed using the GraphPad prism software ANOVA.
Results: IL-4 levels were significantly higher in alum vaccine than the vaccine formulated in MF59, also the IFN-γ cytokine level showed no significant difference between two main groups. TNF-α cytokine shows that alum vaccine is more secreted due to the high inflammation compared with the vaccine with MF59. Total antibody in the third injection, in some dilutions of the commercial vaccine was more than vaccine with MF59.
Conclusion: Significant decrease in IL-4 and antibodies indicates that the tendency of vaccine formulated in MF59 to induce cellular immune responses is higher than humoral immune responses. In addition, the safety and lack of side effects of the MF59 adjuvant can also be considered as another advantage.
Mahnaz Hatami, Faride Mahdavi, Farnoosh Najafi,
Volume 30, Issue 6 (9-2022)
Abstract
Introduction: Student self-assessment is one of the methods of assessing procedural skills that complements existing assessments in dentistry. This study was designed to evaluate prosthetic procedural skills in senior dental students using the self-assessment method.
Methods: In this descriptive cross-sectional study, the level of practical skills of 127 senior dental students of Yazd, Esfahan and Kashan faculties were selected and their procedural skills were assessed by a researcher-made questionnaire. The validity of the questionnaire was confirmed through content validity and its reliability through Cronbach's alpha test (r=0.8).To analyze the data, SPSS 16 statistical software and t-test, Chi-square, ANOVA and non-parametric statistical tests were used at the significance level of 0.05.
Results: Dental students with a mean age of (25.15 ±1.74) were included in this study. The mean of procedural skills score was 115.51 ±11.78 out of 175, which was at an average level. Procedural skills score was not significantly associated with age, gender, marriage, entrance exam rank, university, the level of anxiety during prosthetic application (P>0.05), but the mean score of procedural skills in complete and partial prosthesis was significantly higher in people who interested in prosthesis (P˂ 0.05).
Conclusion: Due to the limitations of the present study, the procedural skills levels in dental prosthesis of senior dental students of Yazd, Esfahan and Kashan faculties was evaluated at an average level. Revision of curriculum- based teaching methods in clinical departments and implementation of new methods for evaluating procedural skills such as DOPS test can be effective in improving the level of clinical skills of learners.
