Showing 5 results for jafari_nodoushan
H Shaker, M Jafari Nodoushan, M Mashayekhian, M Hoseini Kasnavieh, H Basirghafouri, H Reyhani,
Volume 19, Issue 4 (Sep-Oct 2011 2011)
Abstract
Introduction: The aim of this study was to assess the relationship between serum level of aminoterminal pro B-type natriuretic peptide and prognosis in patients with respiratory distress in emergency ward of Rasoul Akram Hospital(Tehran, Iran).
Methods: In this cohort study which was conducted in the emergency ward of Rasoul Akram hospital, after considering inclusion ad exclusion criteria, 62 subjects with respiratory distress entered the study. Blood samples of these patients were used for assessment of NT-Pro-BNP levels Finally, the survival of the patients was defined after 15 days and the levels of NT-Pro-BNP was compared between alive and dead patients. Data was analyzed by SPSS (Ver. 16).
Results: Mean NT-Pro-BNP level was 8141.41(SD=10403.95). 10 patients (16.1%) died (8 females and 2 males) and 52 patients (83.9%) survived after 15 days. Mean NT-Pro-BNP level was 4674.34 (SD=6680.23) and 26170.20 (SD = 7073.80) among survived and died patients, respectively and the difference was statistically significant (p<0.001).
Conclusion: Serum NT-Pro-BNP level can predict the prognosis of patients with respiratory distress due to such diseases as pulmonary edema, COPD exacerbation and CHF.
Aa Jafari_nodoushan, H Aghili, V Herandi,
Volume 21, Issue 4 (Sep-Oct 2013)
Abstract
Introduction: With increasing usage of orthodontic treatments, disinfection of orthodontic appliances and rings is critical for maintaining dental and oral health. Using chemical disinfectants may cause allergic and mucosal disorders. The present study aimed to evaluate Zatariamultiflora essence and to compare it withChlorhexidine (0.2%) mouth wash in controlling experimental plaque from Streptococcus mutant.
Methods: In the current experimental study, 48 Iranian orthodontic rings were immersed in 1×108 CFU/ml Streptococcus mutant suspension. Firstly, Bacterial load on 12 rings was evaluated and then remained rings were randomly divided into 3 groups. They weredecontaminated respectivelyin 0.5mg/100cc Zataria essence, 0.02% Chlorhexidine and sterile distilled water (negative control). Finally the stability rate of Streptococcus mutantviable cells remained on rings was enumerated using culture. Moreover, they were analyzed via SPSS software.
Results: Mann-Whitney test showed a statistically significant differences between mean streptococcus viable cells isolated from the contaminated rings before and after decontamination with Zataria essence and Chlorhexidine (P=0.0001), whereas this reduction wasn’t significant in negative control group (P=0.089). In addition, any statistically significant differences were not observed between zataria essence and Chlorhexidinemouth washes in controlling bacterial plaque (p=0.058).
Conclusion: Since Zatariamultiflora essence solution was proved to be effectivein controlling microbial biofilm on orthodontic rings compared toChlorhexidine,it can be used in further in vivo studies. If the same useful results would be given, it can be regarded fruitful for decontamination of orthodontic appliances.
Jamal Jafari Nodoushan, Ahmad Shirinzadeh, Hamid Reza Soltani Gerdfaramarzi,
Volume 28, Issue 11 (1-2021)
Abstract
Introduction: Hydatid cysts are much less common in the abdomen than in the lungs, and the most common organ involved in the abdomen is the liver, although it is rarely seen in the spleen alone or in multiple organs. The patient was a 25-year-old man who presented with LUQ pain that started one month ago and with a mild non-intermittent nature and it gradually increased. On ultrasound of the patient, multiple cysts in the spleen area were reported. CT scan images also showed evidence of multiple Hydatid cysts. The abdomen was opened. There were several cystic masses that were carefully removed. After 5 days, the patient was in good general condition. oral Mebendazole was prescribed and the patient discharged from the hospital. Although splenic Hydatid cysts are very rare, they are associated with involvement of other organs in the abdomen, as well as the high risk of rupture and anaphylactic shock before and during surgery. This group of hydatid cysts requires special medical care and surgery. Conditions of involvement of several surgical intra-abdominal organs with special care before and during surgery are the basis of treatment of this group of patients.
Mahsa Ashtari-Nejad, Mehran Karimi, Farzad Ferdosian, Farimah Shamsi, Abdolhamid Jafari Nodoushan,
Volume 32, Issue 8 (11-2024)
Abstract
Introduction: Since it is necessary to detect changes in lung function for the follow-up of the patients with respiratory and functional complications caused by COVID-19, in this study, we decided to examine the results of spirometry in children over 5 years old with Covid-19.
Methods: In this cross-sectional study, 52 over-five-year-old children, hospitalized due to COVID-19 for at least six past months, were examined. The participants’ demographic information, respiratory symptoms, underlying diseases, severity of COVID-19 according to WHO, severity of lung involvement in CT scan, type of lung involvement, oxygen saturation at admission as well as FEV1, FVC, and FEV1/FVC were collected and analyzed, the results were analyzed using SPSS version 16 software and t-test and Chi-square tests.
Results: Of all investigated patients،, 26 were boys (50%) and 38 (73.1%) were 5-12 years old. The minimum age of the children was 5 years and the maximum was 18 years. The mean age of children was 3.41±10 years. The FEV1/FVC ranged from 61% to 79% in five patients (9.6%) and from 80% to 100% in 47 patients (90.4%). The FEV1 was lower than 80% in 28 and higher than 80% in 24 patients. FEV1/FVC had no significant relationship with the participants’ age, gender, clinical manifestations, and disease severity in terms of pulmonary involvement, but it had a significant association with blood oxygen saturation level (P: 0.001).
Conclusion: The changes in pulmonary function tests vary in different months following contamination with COVID-19. In the present study, 9% of the patients, who were examined in the sixth month after infection, had abnormal pulmonary function test results. Based on the findings, the pulmonary function test results had no significant relationship with the patients’ age, gender, and clinical symptoms, while it was significantly associated with their blood oxygen saturation intensity.
Mehrsa Nasiri, Zahra Ali Asgari, Mohammad Pezeshki Modarres, Milad Jafari Nodoushan, Soheila Zamanlui Benisi, Salar Mohammadi Shabestari,
Volume 33, Issue 2 (5-2025)
Abstract
Introduction: The field of tissue engineering utilizes interdisciplinary sciences such as to repair or regenerate damaged tissues through the integration of cellular biology, biomaterials, pharmaceuticals, and signaling molecules to repair and reconstruct damaged tissues. Scaffolds, by mimicking the natural extracellular matrix (ECM), play a vital role in guiding cellular activities. Cartilage, as a tissue without blood vessels and nerves, lacks the ability for self-repair, and its injuries are always considered a clinical challenge that affects the lives of millions of people and incurs significant treatment costs. In recent years, the electrospinning technique has gained attention for the production of nanofibers. Electrospun scaffolds, mimicking the extracellular matrix of cartilage, provide a suitable environment for the attachment, proliferation, and differentiation of chondrocytes. The use of nanofibrous scaffolds, along with cells and signaling molecules compatible with the target tissue, is of particular importance for cartilage tissue regeneration. Various natural and synthetic polymers have been used for cartilage tissue regeneration via electrospinning, and their effects on nanofiber morphology have been extensively studied.
Conclusion: This review emphasized recent advancements in the preparation of electrospun scaffolds for cartilage tissue engineering and discussed methods to improve their performance. It also provides an overview of natural, synthetic, and composite biomaterials utilized for electrospinning cartilage scaffolds. The function of nanofibers in delivering signaling molecules for cartilage regeneration is explored. Current challenges in this field are addressed, along with strategies to overcome them, offering potential improvements in cartilage repair techniques and their future clinical application.
