Zahra Soltanian, Behnaz Vanaky, Nasrin Ramezani Fard, Nader Shakeri, Zahra Shams, Fatimah Fakhari Rad ,
Volume 27, Issue 6 (10-2019)
Abstract
Introduction: Type 2 diabetes has many complications, including cardiovascular disease, which is associated with an increase in inflammatory biomarkers. Research has shown that physical activity can reduce inflammatory factors and improve cardiovascular disease. The purpose of this study was to investigate the effect of resistance exercise on some of the inflammatory and anti-inflammatory factors in the heart tissue of type 2 diabetic rats.
Methods: In this study, 18 male rats were selected. Rats were diabetic with nicotinamide and streptozotocin (stz) and then randomly divided into 2 groups of control (n=9) and training (n=9). The training group performed a resistance training program for 8 weeks, 5 days a week. Measurement of TNF-α and IL10 expression in the heart tissue was determined using the one step SYBR TAKARA single-step kit. To compare the difference between the mean of variables between exercise and control groups, independent t-test and t-test were used also to determine the effect of diabetes induction on variables. To determine the relationship between variables, Pearson correlation coefficient and separation correlation coefficient were used. Data were analyzed by SPSS software version 22.
Results: The results showed that the insulin resistance index decreased significantly in the training group compared to the control group. On the other hand, the expression of TNF-α gene decreased and IL10 showed a significant increase (α≤0.05).
Conclusion: The results indicate that resistance training may be effective in modulating the inflammatory factors of TNF-α and IL10 in the heart tissue of type 2 diabetic rats.
Somayeh Ramesh, Mohammad Ali Besharat, Hamid Soltanian-Zadeh, Reza Rostami, Ali Vasheghani Farahani, Hojjatollah Farahani,
Volume 30, Issue 7 (10-2022)
Abstract
Introduction: Vasovagal syncope is the most common type of syncope and recurrent syncope attacks can have a profound effect on the patients' quality of life. The aim of this study was to predict vasovagal syncope based on the variables of body vigilance and alexithymia.
Methods: The present study was a case-control study. The statistical population of the present study included the patients with vasovagal syncope referred to Tehran Heart Center in the year of 1400. Fifty patients with vasovagal syncope and 54 healthy individuals were selected by purposive sampling. Data collection tools included the Body Vigilance Scale and Toronto Alexithymia Scale. Data analysis was performed by logistic regression analysis and using SPSS software version 16 at the level of 0.05.
Results: The results of the Hosmer-Lemeshow Test (P-value = 0.255, χ2 = 3.07) showed good model fit. According to the results of logistic regression test, the coefficient estimate for the alexithymia -0.053 and the body vigilance was -0.017.
Conclusion: Based on the results, in the patients with vasovagal syncope, by designing measures based on reducing body vigilance and alexithymia, they can be helped to improve and reduce syncope episode.
