Showing 6 results for Hasani
A Mirvakili, Mh Baradaranfar, A Hasani, R Jafari,
Volume 15, Issue 4 (Winter 2008)
Abstract
Introduction: Conductive hearing loss due to chronic otitis media (COM) can be treated by surgery. COM, however, may be associated with functional damage to the inner ear. Sensorineural hearing loss (SNHL) due to COM has been found to be significant by some authors, whereas it has been considered negligible by others. The present study aimed to answer the question Does COM cause SNHL ?
Methods: 120 patients with unilateral COM admitted for tympano-mastoidectomy were selected for this observational case-control study. Air conduction threshold (ACT) and bone conduction threshold (BCT) averages were calculated at the speech frequencies (500, 1000, 2000Hz) and 4 KHz, in affected (case ear) and non affected (control ear) and then entered in the questionnaire along with intraoperative findings. Multiple statistical tests were used to clarify the relationships between SNHL and COM.
Results: COM was seen to be associated with SNHL. The Threshold shift was more accentuated at 4 KHz in older patients. SNHL at 4 KHz seemed to be higher than that at the speech frequencies. There was a significant positive relationship between the elevated BCT and duration of COM. The relationship between elevated BCT and cholesteatoma was also significant.
Conclusion: The inner ear is vulnerable to COM. The proximity of the sensory cells to the potential source of harm (inflamed middle ear) may mean higher exposure, as reflected by the fact that sensory cells processing high frequencies are more seriously damaged. SNHL in affected ear is strongly dependant on duration of disease.
L Kohan, M Nasiri, A Habib, A Bolhasani,
Volume 21, Issue 1 (Apr / May 2013)
Abstract
Introduction: Leptin, the obese (ob) gene product, is a cytokine-like hormone secreted mainly from adipose tissue acting on a receptor site in the hypothalamus to inhibit food intake and stimulate energy expenditure. A G-2548G polymorphism in the leptin gene promoter has a strong influence on leptin gene expression and adipose tissue secretion. The aim of this study was to examine the association of the leptin G-2548A promoter polymorphism with leptin plasma level and susceptibility to type 2 diabetes.
Methods: 100 patients with type 2 diabetes mellitus and 100 healthy controls were screened for the presence of G-2548A polymorphism using PCR-RFLP analysis. Body mass index, fasting leptin and fasting glucose were also determined.
Results: Carriers with the GG genotype (20.02±5.6μg/L) had significantly (P<0.001) higher leptin levels than those with the AG genotypes (16.2±5.4μg/L) and AA genotypes (13.42±6.3). Also, LEP -2548GG genotype presented an increased risk of type 2 diabetes (OR: 3.26, 95%CI: 1.5-7.2, P=0.004). In the other words, GG genotypes in the region of -2548 are associated with increased risk of type 2 diabetes.
Conclusion: The present study showed that G-2548A LEP polymorphism is important in regulating leptin plasma level and is associated with risk of type 2 diabetes. Thus, this polymorphism may act as a molecular marker for type 2 diabetes.
Mohammad Ebrahimzadeh Ardakani , Ghasem Dastjerdi, Sepideh Hasani ,
Volume 28, Issue 1 (5-2020)
Abstract
Introduction: Alopecia areata is a fairly common disease characterized by patchy aria of hair loss. The role of psychological factors in the occurrence of alopecia areata has long been discussed. The present study was conducted to determine the frequency of stress and anxiety and depression in the patients with alopecia areata in Yazd City in 2017.
Methods: This study was a cross-sectional study and 50 patients with alopecia areata in Yazd were compared with 50 in the control group in the year 2016. Sampling method was a census and variables, including sex, age, education level, duration of lesion, frequency of relapse, and location of the disease were collected and recorded using a questionnaire. The depression anxiety stress-scale (DASS) (Dass11) questionnaire was used for scoring anxiety, stress and depression. For analyzing the collected data were entered into SPSS version 13.
Results: The results of the study showed that the mean age of the participants in the study was 30.27 ± 8.7, the mean duration of lesion was 23.5±53.52 months and the mean recurrence rate was 1.4±2.2. From 100 participants in the study, 36 (36%) were women and 64 (64%) were men. The mean score of depression (6.8 vs 4.6), anxiety score (6.08 vs 3.5) and stress score (10.06 vs 8.06) were found to be significantly different between the two groups. Also, in women and in the age range of 17-29 years, the mean of depression and anxiety scores was significantly different in the two groups (P-value <0.05).
Conclusion: According to results, it can be concluded that the frequency of depression, anxiety and stress in the patients with alopecia areata is significantly more than the control group.
Hoora Habibi, Arezoo Alaee, Gholamhossein Hasani,
Volume 30, Issue 4 (7-2022)
Abstract
Introduction: The widespread prevalence of depression in society is one of the biggest concerns today. Spiritual health affects depression and plays an important role in improving the quality of life. The aim of this study was to investigate the correlation between spiritual health and depression in general and residency dental students of Islamic Azad University of Medical Sciences
Methods: In this cross-sectional descriptive study, 166 students of 5th semester and higher were selected through census. Demographic questionnaires of Palutzian and Ellison spiritual health questionnaire and Beck depression questionnaire were used to collect data. Participants' information was entered into PASS statistical software version 11 and data analysis was performed using ANOVA tests and correlation coefficients.
Results: In the study, 166 students were included by census. Among all the factors measured, marital status had a direct and significant relationship with spiritual health (P=0.022). Moreover, the history of physical and mental illness had an inverse and significant relationship with spiritual health (P=0.034). Educational status and history of physical and mental illness had a statistically direct and significant relationship with depression (P=0.014, P=0.064). People who had no history of physical or mental illness and were married had higher spiritual health, and people who studied in higher semesters and had a history of physical and mental illness had more depression. Finally, spiritual health and depression showed an inverse and significant relationship (P≤0.0001).
Conclusion: A study of the results obtained from dentistry students showed that there was a significant and inverse correlation between spiritual health and depression.
Masomeh Esmaily, Manijeh Mohammadian, Kazem Mollahasani,
Volume 32, Issue 7 (10-2024)
Abstract
Introduction: Precise acid etching of the tooth surface is a significant factor in the strength of the bracket bond. The current study aimed to determine the effect of different application times of acid etching on the shear bond strength of metallic orthodontic brackets under controlled laboratory conditions.
Methods: Sixty intact premolar teeth were selected for this in-vitro study. The samples were divided into four groups based on the different acid etching times: 20, 25, 30, and 35 seconds. The teeth surfaces were etched with 37% phosphoric acid according to the specified times, and brackets were bonded to the enamel surface using GC Ortho connect composite. Shear bond strength values of the brackets was measured using a Universal Testing Machine. The amount of Adhesive Remnant Index was also observed using a stereomicroscope. Additionally, the surface roughness of the tooth enamel after bracket bonding was examined using SEM. The results related to shear bond strength were analyzed with one-way ANOVA statistical test and using SPSS version 16 software. The non-parametric Kruskal Wallis (Wallis-Kruskal) test was also used to check the frequency of ARI index.
Results: The highest shear bond strength was observed at 25 seconds, and the lowest at 30 seconds. However, there was no significant difference in the shear bond strength of brackets was observed among the four groups (p=0.186). The highest ARI score was observed at 35 seconds, and the lowest at 20 seconds. No statistically significant difference was observed in the ARI scores in different groups. SEM images revealed that the enamel surface porosity was highest at 20 seconds.
Conclusion: The results indicate that the shear bond strength and ARI at different acid etching times do not significantly differ. Therefore, orthodontic bracket bonding can be performed with less acid etching time.
Danial Naghipour, Aref Arminfar, Zahra Sahraneshin Samani, Lida Sepanloo, Hessamedin Babaei, Mohammad Hossein Hasani, Behrooz Yahyaei,
Volume 32, Issue 10 (1-2025)
Abstract
Introduction: Given the widespread issue of methamphetamine addiction and its damaging effects, coupled with the crucial role of the kidneys in maintaining bodily equilibrium, we chose to undertake this study.
Methods: Forty rats were randomly divided into five equal groups: control, methamphetamine, methamphetamine with exercise, methamphetamine with berberine hydrochloride, and methamphetamine with both exercise and berberine hydrochloride. The administration of methamphetamine at a dose of 15 mg/kg intraperitoneally for a duration of 4 days every 12 hours and berberine hydrochloride 100 mg/kg intraperitoneally for a duration of 4 weeks daily has been conducted. Aerobic exercise was performed in the form of running on a rodent treadmill for 8 weeks with moderate intensity. Twenty-four hours following the final exercise and administration of berberine hydrochloride, kidney tissue was extracted and examined under a light microscope, in accordance with the ethics committee's guidelines.
Results: In the methamphetamine group, the glomerulus diameter decreased, hyperemia and tissue disorganization occurred, and the cells of the proximal and distal convoluted tubules were atrophied. In the methamphetamine group, with exercise, there was a decrease in diameter in some glomeruli and changes in hyperemia and an increase in the diameter of blood vessels. In the group treated with methamphetamine and berberine hydrochloride, there was a noted shrinkage of glomeruli and an increase in urinary space. In the group receiving methamphetamine, exercise, and berberine hydrochloride, the quantity and size of glomeruli as well as the spaces between them, were normal and without irregularities.
Conclusion: This research demonstrated that both aerobic exercise and berberine hydrochloride can mitigate the damaging histopathological impacts of methamphetamine on the kidney, indicating that their simultaneous use may offer enhanced protective benefits. effect
