J Yaghini, M Izadi, A Moghare-Abed, H Ebrahim, S Foroughi,
Volume 23, Issue 1 (Mar-Apr 2015)
Abstract
Introduction: Toothpaste should have the most plaque removal efficacy with the least abrasiveness. The aim of this study was to evaluate enamel abrasion induced by four toothpaste types. Methods: In this in vitro experimental study, 24 dental samples were divided into four groups of six. The initial surface roughness was measured with the roughness measuring device. Regarding abrasion test with Daroghar3, Nasim, Crest7 and Crest sensitivity toothpastes, samples were located in V8cross brushing machine. After washing and drying, the secondary surface roughness was again measured with the roughness measuring device. Average wear of samples was analyzed by means of ONEWAY ANOVA. Results: The study results indicated no significant difference among the four types of toothpaste (p=0.855). The toothpastes were ranked in regard with average roughness changes as fallows: Nasim, Crest 7, Crest sensitivity and Daroghar3. Conclusion: The toothpastes investigated in this study did not reveal any difference in terms of wear index.
Abbas Foroughi Pordanjani , Mohsen Salesi, Rasoul Rezaei, Javad Nemati,
Volume 30, Issue 10 (1-2023)
Abstract
Introduction: Inflammation in the brain is known as neuroinflammation and increases TNF-α (Tumor necrosis factor alpha) secretion and activates the TLR4 (Toll-like receptor 4) pathway. The aim of this study was to evaluate the effect of 4 weeks preconditioning with high intensity intermittent training (HIIT) and moderate intensity training (MICT) on TNF-α and TLR4 levels in male Wistar rats.
Methods: The current research was an experimental study.18 male Wistar rats were divided into three groups: high intensity intermittent training (6 heads), continuous moderate intensity training (6 heads) and the control group (6 heads). HIIT program included 6 stages of 2-minute activity with intensity of 85-90% VO2max and 5 stages of active rest for 2 minutes and MICT program with intensity of 65% VO2max with the same duration as HIIT for 4 weeks and 5 days per week was implemented. 48 hours after the last training session, rats were dissected and cortical tissues and layers of mice were extracted for TNF-α and TLR-4 using western blotting. Data analysis was performed using ANOVA test at a significance level of 0.05 With the help of SPSS version 16 software.
Results: The results of the present study showed that TNF-α and TLR4 in the cortex and stratum cerebral areas after 4 weeks of high-intensity and moderate-intensity intermittent aerobic exercise did not change significantly compared to the control group (p≥0.05).
Conclusion: According to these findings, it can be stated that exercise with high or moderate intensity cannot be an effective factor in increasing inflammatory markers in the brain.
