Showing 10 results for Falah
Mr Besharati, Am Miratashi, H Falah Zadeh,
Volume 14, Issue 3 (Autumn 2007 2006)
Abstract
Introduction: Today, Lasik surgery is one of the most common and effective procedures for correction of refractive errors. Less than 1% of patients undergoing Lasik operation suffer from serious and 3-5% suffers from mild complications. Also, results of lasik in most centers are promising. With the recent inauguration of the Lasik center of Yazd, it was decided to evaluate the results and complications of this surgery.
Methods: In this descriptive outcome study, cases were selected randomly and data from files of 230 operated eyes was filled in a specially formatted questionnaire. Data of patients who had been operated upon between March 2003 and March 2004 was gathered and evaluated using SPSS software program with Chi square and Fisher statistical tests. Patients were followed up for 3 months. Residual refractive error in the range
of ± 0.5 was considered as complete treatment and more than ± 0.5 considered as relative.
Results: From the total of 230 eyes, 122 eyes were of women and 108 eyes belonged to men. 24 cases (10.4%) were myopic, 188 cases (81.8%) myopic-astigmatism, 5 cases (2.2%) hyperopic and 13 cases (5.6%) hyperopic-astigmatism .204 eyes were in the age group of less than 40 years and 26 eyes were in the age group of more than 40 years. Based on visual acuity well-being, 225 eyes (97.8%) were treated completely and 5 eyes (2.2%) were treated relatively. Complete eradication of refractive error, 3months after surgery in myopias was 96%, myopic astigmatisms 88%, hyperopias 60% and hyperopic astigmatisms 62%. At 3 months of follow up, 224 cases (97.4%) were without any complications and the rest had few minor side effects.
Conclusion: Lasik operation is a safe and effective procedure for correcting refractive errors with limited complications. Results are comparable with similar studies.
M Rezaeisadrabadi, Mh Dashti, M Anvari, H Falah-Tafti, S Zanbagh,
Volume 19, Issue 4 (Sep-Oct 2011 2011)
Abstract
Introduction: Nowadays, many researches are being conducted in order to evaluate the analgesic effects of different plants which have been used as sedative in traditional medicine. Solanum Melongena is a plant with different theories about its analgesic effects. In this experimental trial research, the effects of intraperitoneal(IP) injection of hydro-alcoholic extract of Solanum Melongena were assessed and compared with different doses of morphine and distilled water in Syrian mice.
Methods: The effects of different doses of Solanum Melongena (1, 10, 100, and 1000µg/Kg), different doses of morphine sulfate (1, 2, and 4 µg/Kg) and distilled water on acute pain was assessed in Syrian mice. Tail flick latency after IP injection was measured for 75 minutes as the index of pain tolerance, using a tail flick apparatus which projects a condensed light stimulus on the animal's tail.
Results: Our findings showed that different doses of Solanum increased analgesia index. This effect was more prominent in 45-60 minutes after IP injections which was significantly greater than the control group (p<0.05(.
Conclusion: Our findings indicated that the hydro-alcoholic extract of Solanum Melongena produces analgesic effect in a dose- related manner.
M Afkhamiaghda, M , H Maleksabet , Amir H Mehrparvar, M Falahati , M Laeh ,
Volume 24, Issue 3 (Jun 2016)
Abstract
Introduction: Social damages as a serious threat will serionsly jeopardize people health. Different factors including uncontrolled population growth, urban development, mechanization of life, disruption of interrelationships, etc. are some causes of social damages that might affect the quality of life. This study was conducted with the aim of investigating the relationship between social damages on the quality of life in Yazd city.
Methods: This study is a descriptive survey one. The target population of this study was the families living in Yazd city. According to Krejcie and Morgan (1970) the sample size was 384. The samples were selected through cluster sampling. A 42-item pathology questionnaire and a 26-item quality of life questionnaire were used to collect the data. The data were analyzed using SPSS.16 software. Pearson correlation coefficient and analysis of variance were used.
Results: The results showed that %95.3 of cases had a low tendency to social damages and there was a significant relationship between social damages and the quality of life. There was also a significant relationship between social damages such as theft, violence, drug abuse, sexual issues, suicide, running from home and quality of life.
Conclusion: The results showed that there was a significant relationship between social damages and the quality of life, which it causes numerous problems for the society and it can have a negative effect on the people’s mental and physical health and decreases the quality of life.
Mm Falah, M Raeeszadeh, E Salimi Naghani ,
Volume 25, Issue 3 (Jun 2017)
Abstract
Introduction: The purpose of this study was to investigate the effect of different doses of aqueous extract of marjoram on spermatogenesis and sperm concentration in cadmium oxidative damage due to the antioxidant quality of extract.
Methods: In the intervational- experimental study, 30 male Wistar rats were randomly divided into 5 groups. Control group, T1, T2, T3 and T4 groups. In the group of T1, 2mg/kg Chloride Cadmium was administered intraperitonialy; T2, T3 and T4 groups, in addition to the chloride cadmium the extract of marjoram at 500, 250 and 125 mg/kg intraperitoneal was administered, respectively, for 10 days. Then, on the last day, after blood collection and separation of serum, TCA was measured. Sperm numbers and percentage of sperm twisted tail were counted in the right epididymis. After measuring the right and left testicular weight and diameter, malondialdehyde and histological studies were examined. The data were analyzed by one way ANOVA analysis and Tukey’s test using SPSS 21.
Results: The highest number and percentage of sperm membrane integrity was in the control group and in T4 (doses of 125 mg/kg of extract) and the lowest in the group receiving cadmium (T1) and this different was significant (P<0.05). The highest concentration of MDA was in the T1 group and the lowest in the group of the dose of 500 mg/kg (T2), respectively. The TCA concentration was the lowest in T1 and highest in T2. The most average sertoli, spermatogonia, spermatocets and Leydic cells was in the control group and the group of 250 mg/kg doses of extract, but the lowest was observed in T1.
Conclusion: The aqueous extract of marjoram with an appropriate dose can have a positive effect on spermatogenesis and control testicular tissue oxidative stress by cadmium
Mohammadali Hosseinpourefeizi , Leila Mehdizadeh Fanid, Gholamreza Noorazar , Mina Adampourezare , Mohammadrezare Golipour Falahi ,
Volume 25, Issue 5 (Jul-Aug 2017)
Abstract
Introduction: Attention deficit hyperactivity disorder (ADHD) is a multifactorial disorder that has defined by hyperactivity, impulsivity and attention deficits. Various neurotransmitters such as dopamine can play a role in its pathophysiology. The aim of this study was to examine the association of two common single nucleotid polymorphisms in DRD4 gene, a 48 bp VNTR polymorphism, with attention deficit hyperactivity disorder risk among Iranian-Azeri population.
Materials and methods: case–control study was performed on 50 children with attention deficit hyperactivity disorder and 50 healthy ones. Peripheral blood samples were used for Genomic DNA extraction by proteinase K method. The collected data were analyzed through chi-square test (x2), with a significance level of 0.05.
Results: considering the obtained results, there was a significant increase in 4/8 genotype frequency between two groups (p<0.05). Although, there was no significant difference in the allele and genotype frequencies in other genotypes between cases and controls (p>0.05).
Conclusion: Our data confirmed the relationship between polymorphism of DRD4 and ADHD. Further studies with larger population of other groups will be required to explain the relationship between DRD4 polymorphism and the risk of ADHD
Sakineh Falahati, Farah Farokhi, Gholamreza Najafi, Ali Shalizar Jalali,
Volume 26, Issue 1 (Apr 2018)
Abstract
Introdution:. Increased plasma cholesterol causes hepatic damages through oxidative stress (OS) induction. There are many investigations about hawthorn effects on lipid reduction and atherosclerosis. The goal of current study was to determine the effects of hydro-alcoholic extract of Crataegus aronia fruit (HECA) and atorvastatin (AVS) on hypercholesterolemia-induced alterations in serum lipid profile and OS in hepatic tissue of female rats.
Methods: In this experimental study, 42 female rats were assigned into 7 groups including control, diet-induced hypercholesterolemia (DIH), DIH + HECA (200 mg/kg/day; Per Oral (PO)), DIH + HECA (400 mg/kg/day; PO), DIH + AVS (10 mg/kg/day; PO), HECA (200 mg/kg/day; PO) and AVS (10 mg/kg/day; PO). After 30 days, blood and hepatic tissue samples were collected for biochemical and histological analyses. Data were analyzed by one-way ANOVA and Tukey's statistical tests using SPSS software.
Results: Hypercholesterolemia resulted in significant increases in levels of serum lipids, hepatic enzymes and malondialdehyde in hepatic tissue as well as reductions in total antioxidant capacity and catalase level in liver compared to control group. Moreover, DIH led to significant increases in diameters of hepatocytes and their nuclei along with inflammation and cellular necrosis in hepatic tissue. Administration of HECA and AVS significantly restored above-mentioned parameters compared to DIH group.
Conclusion: These findings suggest that HECA can play a protective role against hepatic damages in hypercholesterolemic female rats According to the results of this study, the prevalence of obesity is not high in female students (3 %), but it is necessary to pay particular attention to information on obesity and girls' sports in universities, so that the prevalence of this disease is not increased
Mahboobeh Ahmadi, Seyed Mohammad Moshtaghioun, Ali Falahati,
Volume 26, Issue 7 (Oct 2018)
Abstract
Introdution: Recent studies identified the 15q14/15q25 chromosomal region as a susceptibility locus to lung cancer. This region includes CHRNA3, CHRNA5 and CHRNB4, genes, which coding for nicotinic acetylcholine receptor subunits in lungs and brain. The relationship between several polymorphisms in this locus and lung cancer risk has been widely investigated. The aim of this study was to survey the association of CHRNA3 rs1051730 C>T polymorphism with the risk of lung cancer in Iranian patients.
Methods: In this case-control study 96 lung cancer cases in comparison to 100 healthy controls were investigated for the frequency of rs1051730 C>T polymorphism using PCR-RFLP and DNA sequencing methods. The association between the genotypes and allele frequencies with lung cancer was analyzed using chi square and binary logistic regression by SPSS version 22 software.
Results: Allele and genotype frequencies of this SNP was not significantly different between case and control groups. The results of this study indicated no significant association between this polymorphism and lung cancer risk in the population studied (OR = 0.566, 95% CI = 0.239-1.342, P= 0.194).
Conclusion: Our results showed no significant association between polymorphism rs1051730 C>T and lung cancer risk in the population studied. However, according to the different results obtained from the populations of other studies, further studies are recommended along with an increase in the sample size.
Fateme Falah, Farhad Rahmani Nia, Ramin Shabani, Zahra Hojati,
Volume 26, Issue 10 (Jan 2019)
Abstract
Introdution: Ageing is associated with systemic inflammation. MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation and its level was found to decrease with ageing. The aim of this study was to analyze the effect of regular brisk walking on blood circulating levels of miR-146a and plasma levels of Interlukine-6 (IL-6) in sedentary elderly women.
Methods: In this quasi-experimental study, 20 aged women (63.5±3.9 years) were randomly allocated to the endurance training (n=10), and control groups (n=10). Training group (TG) walked at 70-75% maximum heart rate reserve (HRRmax), three times a week for twelve weeks. Control group remained untrained during the study period. Blood samples were collected before and 72 hours after the last session of endurance training for measuring concentration of miR-146a and IL-6. Independent T-test, Paired T-test, Mann Whitney, and Wilcoxon were used after the data analysis base on normalization. Statistical analysis was performed using SPSS software version 24 and the significant level was set at P≤0.05.
Results: The results revealed that the levels of miR-146a increased (P=0.027) and the levels of IL-6 decreased (P=0.001) significantly in response to the endurance training protocol, and these changes were associated with a decrease in body mass index (BMI) (P=0.002).
Conclusion: According to the result of the present study, brisk walking training may be considered as an effective training mode for helping to decrease the blood inflammatory factors. The findings also suggest that microRNAs can be improved, after regular walking, in old adult
Amir Falahnezhad Mojarad, Nastaran Amini, Seyyedmostafa Seyyedashour,
Volume 32, Issue 2 (5-2024)
Abstract
Introduction: A high-fat diet and increased calorie intake increase the prevalence of obesity،,which itself causes many diseases. The studies carried out in the field of investigating the mechanisms related to obesity and its related diseases have introduced the increase of fat mass and as a result the disruption of cytokines as one of the most important influencing factors. Therefore, the aim of the current research was the effect of eight weeks of intense interval training on serum lipid peroxidation indices and adiponectin gene expression in obese mice.
Methods: The current research was experimental with a control group. 24 male rats were randomly divided into three control groups, self-obesity group and self-obesity group with high intensity interval training (HIIT). The normal distribution of the data was evaluated using the Shapiro-Wilk test. Then، in order to compare data between groups، one-way analysis of variance was used, and if it became significant، the data were compared using Tukey's post hoc test at a significance level of P < 0.05.
Results: The findings of this research showed that in the exercise group, there was a significant increase in the state of superoxide dismutase (SOD) compared to the self-obesity group. However,, there was no significant change in the level of malondialdehyde (MDA) and the level of adiponectin gene expression in the liver of self-obesity group and interval training group.
Conclusion: Obesity causes an imbalance in the oxidative status and a disturbance in the production and secretion of adiponectin in the liver tissue of obese mice، and intense intermittent exercise improves the oxidative status, but it does not have a significant effect on the expression of the adiponectin gene
Aabbas Falah Tafti, Mohammad Reza Hakimi Meibodi, Mahammad Safari Khoramabadi,
Volume 33, Issue 4 (7-2025)
Abstract
Introduction: The academic setting and the educational process in dental school can be inherently stressful. Therefore, the aim of this study was to investigate the stressors in the educational setting from the perspective of dental students at Yazd Dental School.
Methods: This descriptive-analytical cross-sectional study was conducted in 2021 among clinical-year dental students at Yazd University of Medical Sciences. Demographic information and stress levels across different areas were gathered through the Dental Education Stress Questionnaire. Data were analyzed using SPSS software version 16 with statistical tests including t-tests, analysis of variance (ANOVA), and Pearson’s correlation coefficient all at a significance level of 0.05.
Results: Among the 240 students who participated, 62.9% were female. The mean total stress score for all students was 80.17 ± 13.7 out of 132. Forty percent of students indicated experiencing high stress, 59.2% reported moderate stress, and merely 0.8% showed low stress levels. No significant differences were identified in the overall stress score or across domains when analyzing gender, parental education, or year of admission (P > 0.05). The overall stress score and the academic efficiency domain were significantly reduced in native students (Yazd residents) compared to non-native students (P = 0.048 and P = 0.016, respectively). No significant differences were observed in other domains (P > 0.05).
Conclusion: The findings of this study indicate that stress levels in the dental setting was moderate to high among most students, with the clinical education aspects being the primary source of stress. Residency status (native vs. non-native) was the only demographic factor that significantly decreased students’ stress levels.
