Showing 4 results for Elmi
A Zainali, K Mansouri, A Rahimdel, Hr Elmi,
Volume 14, Issue 3 (Autumn 2007 2006)
Abstract
Introduction: Even though there is a high prevalence of carpal tunnel syndrome patients, there are very few reliable papers on the study of normal values and changes in sensory and motor latency parameters of the median nerve in the wrist region on the basis of age of patients .This retrospective study was on the basis of 5 years data (1998 -2003) from the electro diagnostic department of Sh. Sadoughi teaching hospital of Yazd.
Methods: In this analytic and observational study, subjects included 1200 patients referring to the electrodiagnostic clinic and also randomly selected healthy patients. Exclusion criteria included systemic diseases such as diabetes, radiculopathy of cervical spine , peripheral neuropathy , positive Phallen test or Tinel sign and atrophy in the thenar region of the hand. Subjects were divided to ten groups on the basis of age. ( 10-80 years ) Sensory and motor latency parameters of median nerve were studied in each age group. All data was evaluated using SPSS statistical software and ANOVA , LSDREST curve regression tests were used for analysis. All values less than 0.05 were considered significant.
Results: In this study, normal values for distal motor latency of median nerve were between 2.5-4.2ms with a ±2SD and mean value of 3.3ms. Increment in this value was mild (0.1ms per decade) after 5th decade of life. This value was calculated using the formula: Distal motor latency:
Normal value for distal sensory latency of median nerve was 2.7-3.7ms with a ±2SD and mean value of 3.2ms. Increment in this value also was 0.1ms per decade after 5th decade of life. This value was calculated by the formula: Distal sensory latency:
Conclusion: It seems that age has a meaningful relationship with distal motor and sensory latencies in the wrist region and therefore in the future, electro diagnostic evaluation along with other increments in these parameters according to age should be considered when evaluating patients with carpal tunnel syndrome.
M Mir, P Mir, S Elmi, M Maleki,
Volume 14, Issue 4 ( Winter 2006 2007)
Abstract
Introduction: Breast Cancer is one of the most important fatal cancers in women. The mean age of breast cancer in Iran is 48.8 years which is very lower than other countries. Selenium can play an important role in reduction of cancer in several ways, for example selenium increases immunity response and protects cells from oxidation of free radicals and also decreases carcinogenic metabolites.
Breast cancer is one of the most important cancers in our country because its incidence is very high and the mean age of patients is very low. Different studies have shown the benefits of selenium in prevention of cancer and since many years selenium has been used as a dietary supplement in advanced countries. Several studies regarding relationship between selenium levels and breast cancer have been done in different countries. We therefore planned a study to evaluate serum selenium levels in breast cancer patients and compare them with a healthy control group.
Methods: We selected 45 patients younger than 48 years old and 33 patients older than 48 years old who had not yet received any therapy (surgery, chemotherapy, etc) for their cancer as a case group and 46 healthy people who were matched with the patients as a control group and included 23 persons younger and 23 persons older than 48 years old. From each participant, 5cc blood was derived and in several stages, serum selenium levels were evaluated using atomic absorption technology. Data about type of cancer, stage, grade, IHC and cigarette smoking were also collected.
Results: The mean Se level was 161.20 μg/l (SD=46.27 μg/l) in the patients and 189.13 μg/l (SD=48.75 μg/l) in the control group that was statistically significant (P<0.001).
The mean Se level in younger patients (< 48 years old) was 169.35 μg/l (SD=47.34 μg/l), while that in older patients (>48 years old) was 155.39 μg/l (SD=46.68 μg/l) that was lower than the control groups. Difference in serum selenium levels between patients and controls in the older group was significant (P=0.007), but in the younger group, it was not statistically significant (P=0.23).
Conclusion: Prescription of selenium as a dietary supplement may have a protective role against development of breast cancer, particularly in older ages and widespread studies need to be performed to prove this postulation.
Key Words: Breast cancer, Selenium
Mehdi Rostamizadeh, Alireza Elmieh, Farhad Rahmaninia,
Volume 27, Issue 5 (10-2019)
Abstract
Introdution: The cells rolled in the formation of bone, regulated glucose metabolism, and increased insulin secretion from pancreatic beta cells and modulated the insulin resistance. Therefore, the present study aimed to study the effects of aerobic and resistance exercises on relation between blood biochemical parameters and body composition with bone turnover markers in overweight men.
Method: In this quasi-experimental study, a total of 36 overweight, young healthy men (age range28-35 years) were randomly assigned to the control (n=14), aerobic exercise (n=11) and resistance exercise (n=11) groups. In the aerobic exercise group, excercisetraining was performedfor 8weeks, three sessions per week (at 55-85% of HRR), and in the resistance exercise group,exercise training was perfprmed in 8weeks for three sessions per week(at 55-75% of 1RM). Body composition and blood samples were assessed from fasting blood samples before and after the 8-week exercise programme. Data wereanalyzed by t-test and ANOVA by SPSS ver.25 Software.
Results: Paired t-test and one-way ANOVA showed that aerobic and resistance training cause the reduction of body composition (P <0.05), increasing the osteocalcin (P = 0.001 and P <0.001) as well as a significant decrease in blood biochemical parameters (P <0.05). Also, Pearson correlation showed that there was no correlation between osteocalcin and blood biochemical parameters and body composition (P <0.05).
Conclusion: The results of this study showed that 8 -week exercise trainings increase osteocalcin levels, which is associated with a decrease in body weight and body fat percentage, particularly lipid profiles. However, despite the differences in mean, there was no statistically significant difference between aerobic and resistance training.
Mohammad Mahdi Bagherpour Tabalvandani, Mohammad Reza Fadaei Chafy, Alireza Elmieh,
Volume 30, Issue 5 (8-2022)
Abstract
Introduction: The aim of this study was to investigate the effect of time and age on morphological changes in male rats.
Methods: For conducting this study, 15 male Wistar rats in three age groups of 2 weeks (150-100 g), 6 weeks (250-220 g) and 96 weeks (320-280 g) were kept in Pasargad Tissue and Gene Laboratory in Tehran City for six weeks and 48 hours later they were dissected and the soleus muscles was extracted. Cross-sectional area and number of muscle fibers were measured by light microscopy. Immunohistochemical method was used to measure sema3a and NCAM proteins of muscle fibers. To determine the differences between the groups, one-way analysis of variance with Tukey post hoc test was used at the significant level of p≤0.05. Statistical analysis was performed by Prism5 software.
Results: The results showed that there was a significant difference in the cross section of muscle fibers between the three age groups: children and young people (p=0.01), children and the elderly (p=0.049), and finally young people and the elderly (p=0.049). There was also a significant decrease in the number of muscle fibers in the age group of elderly compared to children and elderly to young people (p≤0.001). Moreover, sema3a protein expression increased significantly over time between the age groups of children and young (p≤0.048), children and elderly (p=0.0001) and finally young and elderly (p=0.0001). NCAM protein expression significantly reduced in three age groups: children and young people (p=0.048), children and controls (p=0.0001), and young and elderly people (p=0.001).
Conclusion: The results showed that with increasing growth from childhood to youth, hypertrophy increases and decreases in old age, in addition the process of hyperplasia will decrease with age. In addition to proteins involved in axonal growth due to growth decrease and neurodegenerative proteins also increase.
