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Showing 4 results for Behzad
Prevalence of Secondary Hyper Parathyroidism in Hemodialysis Patients
M Rahimian, R Sami, F Behzad,
Volume 15, Issue 1 (Spring 2007)
Abstract
Introduction: Osteodystrophy is one of the long term complications of chronic renal failure and is expressed in two formslow turn over and high turn over. It is an important cause of morbidity in patients with renal failure and if diagnosed and managed properly, many problems of these patients can be resolved. In this study we evaluated the prevalence of hyperparathyroidism in hemodialysis patients and its correlation with different factors. Methods: This study was an analytic, observational study that was done by the cross- sectional method. We formatted a questionnaire for hemodialysis patients who were enrolled in the study over a period of 6 months. Fasting blood samples (5-10c.c) were drawn to measure levels of PTH(parathyroid hormone) ,calcium, phosphorous and alkaline phosphatase. Skull and wrist X-rays were also taken and the radiologist evaluated them with regards to hyperparathyroidism. Results: In the 80 patients studied, prevalence of hyperparathyroidism was 45% (36 patients). 44 patients were diabetics. Among different factors, hyperparathyroidism did not correlate with frequency and duration of dialysis, age, sex ,familial history, diabetes, hypertension , bone pains, muscle weakness, purities and level of calcium and phosphorous. But there was a significant relationship between hyperparathyroidism and alkaline phosphatase levels and radiological findings. Conclusion: We can use alkaline phosphatase levels and/or radiographic changes for evaluation of renal osteodystrophy in hemodialysis patients and prevent complications by early diagnosis and proper management.
The Effect of Mindfulness-based Cognitive Therapy on the Mental Health of Female Patients Suffering from Multiple Sclerosis
P Ahmadi-Shooli , Ar Feily, Islamic Azad University S Behzadipour,
Volume 23, Issue 10 (Jan 2016)
Abstract

Introduction: Multiple sclersis (MS) can involve approximately all aspects of life, which leads to different problems for a person such as psychological problems. Therefore, the present study
aimed to evaluate effectiveness of mindfulness-based therapy on the mental health of female patients suffering from MS.

Methods: In this quasi-experimental study, the study sample consisted of 24 patients suffering from MS, who were selected via convenience sampling method. Once the participants were homogenized in regard withg their age, occupation, and education, they were devided into an experimental group (n=12) and a control group (n=12). The study instrument consisted of the general health questionnaire (GHQ-28). The experimental group attended 8 sessions—each lasting 2 hours—of training on mindfulness-based cognitive therapy, whereas the control group did not receive any interventions. In order to analyze the study data, SPSS software( ver, 22) was used via Multivariate analysis of co-variance (MANCOVA).

Results: As the study results demonstrated, the difference between experimental and control groups was proved to be significant in terms of mean scores of mental health and its dimensions (p=0.0001).

Conclusion: The study results supported the effectiveness of mindfulness – based cognitive therapy on mental health of female patients . It can be concluded that this method has ameliorated mental health of MS patients.


Effects of Aerobic Training on Caspase-3 Expression and Apoptosis in Hippocampus of Rats after Brain Ischemic Stroke
Behzad Dehghanizadeh, Ziya Fallahmohammadi, Abdolhossein Taheri Kalani, Sayed Javad Mirghani,
Volume 30, Issue 1 (4-2022)
Abstract
Introduction: Although exercise is an effective strategy for preventing and treating stroke, the extent of this effect seems to depend on when exercise begins. Apoptosis plays a critical role after stroke. However, it is unclear whether early exercise inhibits apoptosis after stroke? The aim of this study was to determine the effect of eight weeks of early aerobic training after stroke induction on caspase-3 protein expression and apoptosis in the hippocampus of male Wistar rats.
Methods: In this experimental study, 32 adult male Wistar rats (weighting 210-252 gr) were purchased and randomly divided into four groups: sham, ischemia, training and ischemia+ training groups. Ischemia was induced by the occlusion of both common carotid arteries (CCA) for 45 min. Aerobic training was initiated at 24 hours after induction of ischemia, for eight weeks for 20-50 minutes and at a speed of 18-30 meters per minute in each session and five sessions per week. Forty eight hours after the last training session, rats were sacrificed, then using immunohistochemical staining technique of caspase-3 protein expression and the rate of cell apoptosis were measured by hematoxylin and eosinophil (H&E) staining method in hippocampus of rats.
Results: The expression of caspase-3 protein and apoptosis in the hippocampus of rats in sham and training groups were significantly lower than in the ischemia and ischemia+ training groups (both; p<0.0001). Moreover, in the ischemia+ training group, the expression of caspase-3 protein and apoptosis showed a significant decrease compared to the ischemia group (p<0.0001).
Conclusion: Based on the results of this study, it can be said that eight weeks of early aerobic training can reduce the lesions induced-cerebral ischemia by reducing the expression of cell death-causing factors.

 

Investigating the Effects of 8 Weeks of Resistance Training on the Levels of P53 and Nrf2 Proteins in Kidney Tissue in Diabetic Rats with Morphine Withdrawal Syndrome
Behzad Azadbakht, Abbas Saremi, Mojtaba Khansooz,
Volume 31, Issue 10 (1-2024)
Abstract
Introduction: The effect of exercise training on kidney tissue in the condition of diabetes with morphine withdrawal syndrome is unclear. The aim of this study was to investigate the effect of 8 weeks of resistance training on the levels of P53 and Nrf2 proteins in kidney tissue in diabetic male rats with morphine withdrawal syndrome.
Methods: This experimental study utilized a sample of 32 Wistar rats. Following the induction of diabetes, the Wistar rats were randomly divided into four groups of eight based on their weight: diabetes, morphine diabetes, diabetes with resistance training, and morphine diabetes with resistance training. The oral technique was employed for a duration of 21 days to establish a reliance on morphine.. The resistance training protocol was implemented for 8 weeks. At the end, all mice were anesthetized, killed and their tissue was extracted. The variable protein levels of this study were measured by ELISA kits. Data were analyzed using one-way analysis of variance and Tukey's post hoc test with the help of SPSS version 16 software at a significance level of p ≤ 0.05.
Results: Resistance training caused a significant decrease in P53 in the groups of diabetes + resistance training (P=0.006) compared to diabetes and morphine diabetes + resistance training (P=0.012) compared to morphine diabetes group. Similarly, a significant decrease in Nrf2 was observed in the morphine diabetes + resistance training group (P=0.013) compared to the morphine diabetes group.
Conclusion: Resistance training probably reduced kidney tissue damage in diabetic and diabetic rats with withdrawal syndrome by reducing P53 protein, which indicates the protective effect of resistance training on kidney tissue in pathological conditions.
 

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