Showing 10 results for Azari
P Dabirmoghadam, Sh Azari, F Ezoddini-Ardakani, Ar Sadr-Arhami, Hr Mansourian ,
Volume 14, Issue 2 (Summer 2007 2006)
Abstract
Introduction: Mandibular fracture is the most common facial bone fracture due to facial trauma. A variety of imagings have been used for diagnosis of mandibular fractures. However, the choice of imaging for diagnosis of mandibular fractures is controversial.Present study compares the accuracy of the three most common imaging methods in mandibular fracture diagnosis panoramic radiography, coronal CT and axial CT scan.
Methods: This cross sectional diagnostic study was performed on 45 patients with a clinical diagnosis of post traumatic mandibular fracture at the ENT department of Shaheed Sadoughi hospital,Yazd. Patients underwent panoramic radiography and CT scan (both axial and coronal). Then, all were operated for reduction of fracture (either closed or open) and fixation done with arch bar and MMF in combination with or without rigid internal fixation. The physical examination and observation during operation was considered as the exact diagnosis. The radiological findings were reported by three different radiologists. Finally, the accuracy and sensitivity of each method was compared with the other methods.
Results: There was no significant difference between the accuracy of panoramic radiography and coronal CT scan in all of the regions, but the accuracy of axial CT was significantly less than coronal CT in certain regions.
Conclusion: The accuracy of panoramic radiography and coronal CT scan in diagnosis of mandibular fractures is the same or higher than axial CT scan. Additionally, panoramic radiography is more accessible and less expensive than coronal CT scan. Therefore, this study recommends oral panoramic radiography as the first radiologic test for diagnosis and localization of mandibular fracture
Gh Hassanshahi-Raviz, Mr Hajizadeh, Mr Mirzaee, Aa Pourshanazari, Ma Rezvani, R Vaziri, A Dickson,
Volume 15, Issue 2 (Summer 2007)
Abstract
Introduction: Chemokines are low molecular weight proteins (8-17kDa) with the main role of immune cells recruitment to injured tissues. IP-10/Mob-1 is a CXC chemokine and different cell systems in response to external stimulation produce this chemokine. Various signaling pathways are used by cell and tissue systems to regulate production of proteins e.g. chemokines. Therefore we have investigated some of these pathways leading to production of IP-10/Mob-1 by primary cultured hepatocytes.
Methods: In the present study, hepatocyts were isolated from male Sprague Dawley rats and cultured on Waymouth medium in presence and absence of different inhibitors such as SB203580, MG132, KN62 and Staurosporine for indicated time points. Supernatant medium of culture was centrifuged and proteins were isolated by SDS-PAGE and transferred to nitrocellulose membranes, then membranes were incubated with IP-10/Mob-1 antibody overnight and followed by incubation with secondary antibody and then IP-10/Mob-1 was detected by ECL.
Results: We showed that the expression of IP-10/Mob-1 has been decreased in presence of Staurosporine (10 and 50μM), SB203580(50μM) MG132 (20μM) and KN62 (10 and 20μM) but did not change in absence or lower concentrations of these inhibitors.
Conclusion: Hence, these in vitro data may aid to a better understanding of the pathways in chronic liver injuries and identify clinical studies that may aid in treatment or prevention of these conditions. Furthermore, there may be further potential to prevent changes to hepatocyte phenotype and allow isolation of hepatocytes with a greater physiological phenotype. Therefore it could be concluded that all of these pathways are used by hepatocytes regarding expression of IP-10/Mob-1.
Z Safari, M Saadati, Sh Nazarian, M Heiat, M Mirzaei,
Volume 18, Issue 2 (Jun/Jul 2010 2010)
Abstract
Introduction: Annually, more than 14 million people are reported to be infected with Leishmaniasis all over the world. In Iran, this disease is seen in the form of cutaneous and visceral leishmaniasis, of which the cutaneous form is more wide spread. In recent years, cutaneous leishmaniaisis is diagnosed by PCR utilizing specific primers in order to amplify different parasite genes including ribosomal RNA genes, kinetoplast DNA or tandem repeating sequences. The aim of this research was to detect early stage cutaneous leishmaniasis using Multiplex-PCR technique.
Methods: In this study, 67 samples were prepared from patients with cutaneous leishmaniasis. DNA was extracted with phenolchloroform. Each specimen was analyzed using two different pairs of PCR primers. The sensitivity of each PCR was optimized on pure Leishmania DNA prior to use for diagnosis. Two standard parasites L. major and L. tropica were used as positive control.
Results: DNA amplification fragments were two 115 bp and 683 bp for AB and UL primers, respectively. The sensitivity of two primers was not equal for detection of L. major and L. tropica. The sensivity of PCR with AB primer was 35 cells, while that for UL primer was 40 cells.
Conclusion: The results of this study indicate that PCR is a sensitive diagnostic assay for cutaneous leishmaniasis and could be employed as the new standard for routine diagnosis when species identification is not required. However, the ability to identify species is especially important in prognosis of the disease and in deciding appropriate therapy, especially in regions where more than one type of species and disease are seen by clinicians.
M Alagheband, Ar Aghayousefi, M Kamali, M Dehestani, F Haghiroalsadat , T Nazari , Mh Sheikha,
Volume 19, Issue 1 (Mar-Apr 2011)
Abstract
Introdution: Presence of mentally retarded children as a source of pressure can jeopardize the general health of parents, especially mothers. The range of effect depends on the recognitive evaluation and the individual. The aim of this study was to investigate the effect of coping-therapy on mental health of mothers with genetically and non genetically mentally retarded children referring to Yazd clinical center.
Methods: This study was semi experimental and included 40 mothers with mentally retarded children studying in schools supported by the welfare organization of Yazd in 2009- 2010 and were selected by available sampling method. They were divided to two groups case and control. Before any therapy, all of the mothers answered a general health questionnaire(GHQ28). In the next step, coping-therapy was performed on the case group. In the end, all of the mothers answered the same questionnaire(GHQ28) and data were analyzed by covariance method and t test.
Results: The research indicated that coping-therapy has a positive effect on the mental health of mothers with genetically mentally retarded children. This effect is similar on mothers of children with non genetically mental retarded children. Coping-therapy decreases the somatic signs of depression in mothers and improves their sleeping and social efficacy. There was no association of age and educational level of mothers with coping-therapy.
Conclusion: Coping-therapy can improve the mental health of mothers of both genetically and non genetically mentally retarded children
J Mohiti Ardekani, Z Akbarian, A Nazarian,
Volume 19, Issue 3 (Jul-Aug 2011 2011)
Abstract
Introduction: Diabetes is one of the most prevalent metabolic diseases in the world. It affects 6.6% of world population and about 3 million individuals in Iran. Cumin (Cuminum Cyminum L) is a plant used in traditional Iranian medicine to cure obesity, and some recent studies have suggested that Cumin could have a role in diabetes treatment and reduction of lipid levels. In this study, we investigated the Cumin oil effects on serum glucose and lipid levels of rats.
Methods: We divided 24 male rats of Wistar race into 6 hexadic groups the control group with normal regimen(group a), the Cumin oil group with normal regimen(group b), the control group with high fat regimen(group c), the Cumin oil group with high fat regimen(group d). The consumed dosages of Cumin oil were 400 µg/kg and 3mg/kg, respectively which was administered by Gavages (tube feeding). Samples from the hungry rats were taken during three various periods including the first day of the study, 20th day (the beginning of the medicine usage) and 55 th day (the end of the medicine usage) in order to measure their serum glucose and lipid levels.
Results: The results of this study showed a significant decrease in glucose(p=0.007), cholesterol(p=0.001), triglyceride(p=0.002), LDL (p=0.004) levels and a significant increase in serum HDL levels(p=0.05).
Conclusion: Cumin oil administered via Gavages can significantly affect the serum glucose and lipid levels.
L Ajori, L Nazari , Sh Marefat , Z Amiri,
Volume 20, Issue 5 (NOv-Dec 2013)
Abstract
Introduction: This randomized clinical trial (RCT) was conducted to evaluate whether use of music could reduce the pain and duration of labor.
Methods: Between 2010 and 2011, a total of 99 women at 38 weeks or greater with spontaneous labor were randomized to fast music, slow music, and control groups. Labor pain was assessed on a visual analogue scale (VAS) at beginning of the active phase and then every 1 hour. Duration of active phase and second stage of labor was recorded. Analysis of all proportions was carried out using t- test, Mann-whitney test, and Pearson’s chi-square test when appropriate.
Results: Patients in the fast music group revealed lower VAS scores at all time after music therapy, except fourth hour, and in the first and fifth hours, this differences were significant. In slow music group VAS scores, only in fifth hour were significantly lower than those of control group. Duration of labor was significantly lower in the fast music group than control.
Conclusion: Listening fast music in the active phase of labor decreased pain and duration of labor.
Masoud Abdollahi, Hossein Honari, Shahram Nazarian, Mehdi Masoudi Kerahroudi,
Volume 24, Issue 12 (Feb-Mar 2017)
Abstract
Introduction: Plant ribosome inactivating proteins act as N-glycosidase enzyme and produce by several family of Caryophyllaceae such as Saponaria Officinalis. Different Isoforms of RIPs expressed by Saponaria Officinalis. SO6 isoform depurinate Adenine 4324 in the conserved GAGA loop of 28SrRNA and disrupts protein synthesis. The aim of this study was expression of SO6 isoform in E.coli and investigation of antibody titer in rats.
Methods: In this experimental study, SO6 synthetic gene was excised from recombinant pUC57- SO6 plasmid with BamHI and SalI restriction enzymes and subcloned into pET28a (+) expression vector. The expression of recombinant protein was induced by IPTG. Recombinant SO6 was purified by nickel affinity chromatography. Western blotting was performed to confirm the recombinant protein. Rats were immunized intraperitoneal with purified protein and IgG serum titer was assayed by ELISA.
Results: PCR reaction and enzyme digestion confirmed subcloning of SO6 gene into pET28a (+) expression vector. A 29.5kDa protein band on SDS-PAGE showed a high level of recombinant protein expression. Polyclonal antibodies recognized SO6. ELISA confirmed significant antibody titer after injection of protein in test group compared with the control group.
Conclusion: The recombinant purified SO6 antigen can be used for anti-cancer and vaccine candidate research.
Sara Jorkesh, Rasool Nazari,
Volume 26, Issue 12 (Mar 2018)
Abstract
Introdution An increase in the population of elderly people in Iran in the future is an inevitable and significant process that should be examined from a variety of dimensions. The purpose of this study was to investigate the future study of Iran's elderly sports using cross-impact matrix.
Methods: In this research cross impact analysis approach has been used as one of the future study methods. Initial variables of research was gathered using half-interviews with participants scholars and specialists in sport sciences, psychologists, social workers, sociologists, nurses, the managers of sanity offices, the Welfare Organization and the social council of municipality. Data validation criteria recommended by Lincoln & Guba was confirmed and then analyzed using Micmac software.
Results: Results from using cross impact analysis approach suggested that the six key factors, namely, attention to the elderly, the creation of special organs for the elderly, the allocation of funds, the modeling of other countries, the design of long-term programs and the establishment of process-oriented strategies werethe most important factors for the future of elderly sports in Iran that should be considered in planning.
Conclusion: The researcher has tried to analyze Iran's futur study of elderly sports. The results and findings of the research process and the proposed strategic recommendations can provide an appropriate setting for policymaking and designing strategies and policies for strategic managers in the elderly sports sector
Mr Bijan Pirnia, Mrs Tahereh Kashani Khatib, Mrs Sholeh Nazari, Mrs Samaneh Haghiry, Mrs Solmaz Madadi Varzeghani, Mrs Maryam Faryammanesh,
Volume 27, Issue 1 (Apr 2019)
Abstract
Introdution: Parent-child interactive therapy is considered as an emerging approach to reduce child behavioral problems, which relies on improving parent-child relationship. The aim of this study was to investigate the effectiveness of parent-child interactive group therapy on the improvement of affective index in children with methadone-treated parents.
Methods: In a clinical trial in the form of a semi-experimental study during the period from June to November 2015, among families who were referred to Bijan Center for Substance Abuse Treatment in Tehran who had children of preschool age, 40 children were chosen after screening based on the positive and negative affect schedule (PANAS) and the child behavior checklist (CBCL), they were randomly assigned to two experimental and control groups. The treatment program was presented to the experimental group for 8 sessions per week. The validity of urines samples was investigated by immunochromatography. Adherence to treatment in the form of urine test was considered as the primary outcomes and affective index was considered as secondary outcomes. Data were analyzed using chi square and multivariate analysis of covariance.
Results: The primary outcomes showed that the frequency of positive urine tests was not significant during the treatment process (p = 0.88). Secondary outcomes showed that interactive treatment in the experimental group was associated with an increase in positive mood (p = 0.44) and a decrease in negative mood in comparison with the control group (p = 0.48).
Conclusion: The findings of this study indicate the importance of parent-child interactive styles in the prevention and treatment of psychological disorders during the development periods, and it can be considered in designing appropriate interventions.
Reza Rezaee, Mehdi Raadabadi, Hamed Nazari,
Volume 28, Issue 7 (10-2020)
Abstract
Introduction: After traffic accidents and falls, burns are the third leading cause of accident deaths. Burns are one of the most devastating forms of injuries, and survivors after recovery need many years of rehabilitation and emotional, physical, and economic support. The aim of this study was to identify the factors affecting a comprehensive management system for the treatment of burn patients with qualitative content analysis approach.
Methods: This qualitative study was conducted using content analysis method in 2018. The sample consisted of 20 experts in burn scope who were selected through purposeful sampling. Data were collected using a semi-structured face-to-face interview. Content analysis method and MAXQDA 10.0 software were used for data analysis.
Results: Analysis of qualitative findings showed that factors affecting burn treatment management included 6 categories of pre-hospital care (5 subcategories), hospital care (12 subcategories), rehabilitation services for burn patients (5 subcategories), medical equipment (1 subcategory), prevention (3 subcategories) and human resources (3 subcategories).
Conclusion: According to the results, corrective actions in the field of prevention, pre-hospital, treatment and rehabilitation should be considered. Actions such as home changes, safe child monitoring, burn prevention while cooking, equipping all ambulances with basic equipment related to various types of burns, providing training to pre-hospital ambulance staff on care of burn patients, standardizing bed facilities, the burn section and attention to social skills promotion program is suggested.