Showing 6 results for Abtahi
F Rashvand, Z Moshtagh Eshgh, M Farvid, M Abtahi, Z Amiri, H Madani,
Volume 19, Issue 3 (Jul-Aug 2011 2011)
Abstract
Introduction: Multiple Sclerosis Disease is the most common neurological demyelinization disorder in young adults that leads to their disability. Because of the side effects of treatment drugs, it seems that another method should be used. Correct nutrition is one of these methods. The aim of this research was to determine the effects of nutrition on activity of daily living in MS patients referring to the Iranian MS society in 2010.
Methods: In this quasi- experimental study (before and after investigation), 40 MS patients were selected on basis of purposive and accessible sampling method. The data was collected via questionnaires. The intervention comprised of correct nutrition algorithm education for 12 weeks. All questionnaires were filled before and after the intervention by subjects and then pre/post intervention data was analyzed with SPSS 16 software. Statistical tests included Student paired and T tests.
Results: The statistical analysis showed that there was a significant difference between mean score of ability of activity of daily living of MS patients before and after intervention(P<0.001), thus confirming the hypothesis of the study.
Conclusion: According to results, it is recommended that nutrition pattern (simple, cheap without side effects and noninvasive procedure) should be used to improve the levels of activity of daily living in MS patients.
N Abtahi, H Eimani, A Vosough, Ah Shahverdi, R Fathi,
Volume 22, Issue 2 (May-Jun 2014)
Abstract
Introduction: One of the challenges facing ovarian transplantation is overcoming the ischemia/ reperfusion injury. When blood supply to the implanted tissue is suboptimal (immediate post implant period), ultrasound therapy has been shown to increase mass transport. The aim of this study was to investigate the effect of ultrasound on heterotopic transplantation of mouse ovarian tissue.
Methods: Adult female NMRI mice were selected and divided into the control, sham and experimental groups. In the experimental group, left ovarian tissue, after auto transplantation into the back muscle, underwent ultrasound exposure with intensity of 0.3 w/cm2, frequency of 3MHz & pulse mode of 1:4, for five minutes daily. The transplanted ovaries were removed and immediately fixed for histological study. Furthermore, rate of angiogenesis was assessed by immunohistochemistry Cd31 test.
Results: The study results showed that the CD31 angiogenic factor was expressed more in the irradiated animals than in control group animals and ultrasound-therapy resulted in better follicular preservation.
Conclusion: The ultrasound therapy can improve preservation of ovarian follicle .This is probably due to acceleration of angiogenesis and increase in production of growth factors by low intensity pulse ultrasound.
M Abtahi Froushani, S Nafisi, H Esmaili Gorchin Ghale, B Mansori Motlagh,
Volume 23, Issue 5 (Jul-Aug 2015)
Abstract
Introduction: Trifluralin is a widely-used herbicide that inhibits proper cell proliferation in the root of plants. Therefore, the present study was conducted in order to investigate the effects of trifluralin on immune system of the NMRI mice challenged with sheep red blood cells(SRBCs).
Methods: The study population consisted of 14 male NMRI mice randomly catagorized into two equal groups and then were immunized with SRBC. The mice in the treatment group received trifluralin (5omg/kg orally-0.01 LD50) per day from the beginning of the study,which continued for 2 weeks.
Results: The results of the current study indicated a significant decrease in the levels of anti-SRBC antibody and simultaneously a significant decrease in the delayed type of hypersensitivity(DTH) in the treatment group compared to the control group. Furthermore, the level of respiratory burst of phagocytic cells, the lymphocyte proliferation index of splenocytes, as well as the spleen weight index significantly decreased in the treatment group compared to the control group.
Conclusion: The study findings revealed that trifluralin even in the low dose may lead to a significant suppression in regard with many aspects of the immune system.
H Zirak Marangalu , S Khezri , M Abtahi,
Volume 25, Issue 3 (Jun 2017)
Abstract
Introduction: Curcumin is a bright yellow chemical produced by some plants like Turmeric. The
anti-inflammatory effects of Curcumin were recorded in some studies. This study was done to investigate the effects of the Curcumin on the physiological functions of rat blood monocytes.
Methods: This study was an experimental one. The study population consisted of 20 rats randomly categorized into the treatment and control groups. Curcumin was orally administered to treatment group in daily doses of 200 mg/kg from the beginning of the study and continued for 4 weeks. The control rats received PBS at the same volume. At the ends, the blood samples were taken from the rats and the monocytes were isolated under a ficoll-hypaque gradient. Isolated monocytes were challenged with opsonized yeast and the functions were evaluated.
Results: The results showed that the monocytes isolated from the control and treatment groups have not shown any significant differences in phagocytosis after challenge with opsonized yeast (p=0.1). Nevertheless, the respiratory burst (P=0.009) and nitric oxide production (P=0.03) were decreased in curcumin treated rat compared to the control rats. Albeit, the biological activities of monocytes in the treatment group was increased compared to the monocytes isolated from the control group (P=0.0001).
Conclusions: Collectively, it seems that curcumin is a natural source to intervene the monocytes functions especially in autoimmune diseases so that monocytes hyperactivity causes immunopathological conditions.
Alireza Mohammadzadeh, Seyed Hossein Abtahi Eivary, Nasim Khajavian, Jafar Hajavi,
Volume 31, Issue 8 (11-2023)
Abstract
Introduction: Helicobacter pylori infection is known as one of the health problems in the world, and the concurrent infection of diabetics with Helicobacter pylori contributes to health and economic problems in the world. The present study was conducted to investigate the prevalence of Helicobacter pylori in patients with type 2 diabetes in Gonabad City, Iran.
Methods: This case-control study was conducted in Gonabad City, Iran. The number of participants in the study was 168. The method was simple random sampling and the study population was typing 2 diabetic and non-diabetic people who were referred to Gonabad health centers. After obtaining informed consent from the patients, 4 milliliters of venous blood were collected from the patients with type 2 diabetes and the control group, and IgG antibodies against Helicobacter pylori and Fasting Blood Sugar and Glycosylated Hemoglobin (HbA1C) were measured by ELISA and Colorimetric method, respectively. After entering the data into SPSS version 16 software, they were analyzed using independent tests, chi-square tests, and logistic regression tests.
Results: In the present study, 71.4% of type 2 diabetes patients had IgG antibodies against H. pylori bacteria. The odds ratio of diabetes in the patients with positive IgG was 1.37 times that of patients with negative IgG, and this relationship was statistically significant (P=0.003).
Conclusion: The present study showed that H. pylori was more common in diabetic patients than non-diabetic ones, and in diabetic patients, there was no statistically significant relationship between the duration of diabetes, family history of diabetes, and smoking history with Helicobacter pylori infection.
Corresponding Author: Jafar Hajavi
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Farnaz Tajbakhsh, Somayeh Tavana, Mohammad Kazemi Ashtiani, Naeimeh Sadat Abtahi, Leila Sadat Tahaei, Ashraf Moini, Rouhollah Fathi,
Volume 32, Issue 10 (1-2025)
Abstract
Introduction: Ovarian tissue freezing is the most effective method to maintain fertility for immature girls and women diagnosed with cancer. Nonetheless, because of the chance that malignant cells might reappearing following tissue transplantation, it is crucial to isolate the follicles from the frozen-thawed ovarian tissue of these individuals and employ them in the process of in vitro maturation process or artificial ovarian framework. This study aimed to assess the application of neutral red (NR) vital dye alongside collagenase IA for effectively isolating viable follicles from the vitrified human ovarian tissue samples.
Methods: Two categories existed: the category with NR and the group without NR. Chopped (0.5×0.5 mm) strips of vitrified-warmed ovarian tissue from 10 transsexual individuals were placed into two falcon tubes with HTCM and Collagenase IA (1mg/ml). Neutral red (NR) was introduced to one of the falcons. Follicles were then isolated mechanically. The morphology, size, and viability of the follicles were assessed. The condition of the follicles was evaluated using fluorescent staining methods involving Calcein-AM and Ethidium homodimer-I. The t-test method was used to evaluate the data.
Results: The number of isolated follicles with Neutral Red (46.50±25/02) exceeded those without NR (6.6±5.58; P < 0/0001). Additionally, according to the morphological studies, a majority of the isolated follicles from the transsexual ovarian cortex were primordial (77.4%), and primary (21.12%) follicles, with only a small number of secondary follicles (1.4%) identified in these tissues. Live/dead staining verified the viability of isolated follicles by displaying a green hue.
Conclusion: The finding indicates that combining collagenase I with the vital dye Neutral red significantly facilitates the of follicles from dense human ovarian tissue.
