Phage Therapy: Past، Present and Future

Fathi, Farzaneh; Zeinoddini, Mehdi

doi:10.18502/ssu.v32i11.17780

Volume 32, Issue 11 (2-2025) JSSU 2025, 32(11): 8366-8379 | Back to browse issues page

‎ 10.18502/ssu.v32i11.17780

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Fathi F, Zeinoddini M. Phage Therapy: Past، Present and Future. JSSU 2025; 32 (11) :8366-8379
URL: http://jssu.ssu.ac.ir/article-1-6328-en.html

Phage Therapy: Past، Present and Future

Farzaneh Fathi

, Mehdi Zeinoddini ^*

Abstract: (72 Views)

Introduction: As viral agents، phages serve a significant purpose in molecular biotechnology. These viruses are considered as ideal tools in this field and recent studies revealed their wide potential in biomedicine. Research on phages showed that these viruses have the potential to develop new treatments، encompassing phages as anti-cancer solutions، transporters of imaging substances، tissue repair، medication distribution، vaccine formulation، and addressing COVID-19. The bactericidal effect of phage via CRISPR-Cas technology is also used to treat antibiotic-resistant bacteria. In this review study، we will explore the key role of phages in the research and development of future treatments.
Conclusion: Phages have arisen in the field of bioengineering with great potential in tissue engineering، vaccine development، and immunotherapy. The genetic composition of phages can be utilized to develop new vaccines and antigen display systems. Phages have opened new opportunities to target specific molecular determinants of cancer cells.

Keywords: phage therapy, phage display, phage vaccine.

Full-Text [PDF 1107 kb] (59 Downloads)

Type of Study: Review article | Subject: Microbiology
Received: 2024/11/14 | Accepted: 2025/02/3 | Published: 2025/02/3