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Mashroteh H, Khajeh Mehrizi M, Nabizadeh N, Tehrani Dehkordi N. Optimizing of Nonwoven Fabric Properties Using Nano-bio Materials for the Wound Dressing Application. JSSU 2020; 28 (4) :2547-2563
URL: http://jssu.ssu.ac.ir/article-1-4939-en.html

Introduction: In addition to its protective role, dressings not only prevent infection, but also accelerate wound healing process. In this study, the influence of optimizing the properties of the calendered needle-punched nonwoven fabrics using the finishing materials of Honey, Aloe Vera, Chitosan and Nano Argentum Nitrate for the end-usage as dressing has been investigated.
Methods: The prepared samples of the needle-punched nonwoven fabrics were firstly calendered and then, tested for the fundamental expected physical characteristics in the dressing purpose, i.e. crease recovery magnitude, air permeability, etc. in order to distinct initial optimized sample. In the following, the antimicrobial finishing process was carried out on the primary sample by the four studied finishing materials. The finished samples were finally analyzed simultaneously from the antimicrobial aspect and also, for the same physical properties of the dressing, as tested before, to distinguish the ultimate optimized sample. The bacteria of Staphylococcus aureus and Escherichia coli (E.coli) were also employed for antimicrobial tests.
Results: The results demonstrated that combination of four finishing materials of Nano Silver 1%, Aloe-Vera 20%, Honey 7% and Chitosan 1% improved desired properties for wound dressing application in comparison to the other samples from one side and, showed no cellular toxicity and allergy from the other side. The FTIR’s results also implied stretching bonding of hydroxyl group in 3200-3400 wavenumber.
Conclusion: The needle-punched nonwoven fabric finished by the recommended antimicrobial materials can be considered as wound dressing, regarding to sufficient physical properties and hygienic condition.