Volume 18, Number 6 (Jan- Feb 2011)                   JSSU 2011, 18(6): 521-530 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hokmollahi F, Rafati H, Riahi H, Hakimi M, Aliahmadi A, Heydari H, et al . Collection and Identification of a Medicinal Mushroom, Phellinus Conchatus in Iran and Investigation of the Antibacterial Activity of Total Methanol Extract and Fractional Extracts. JSSU. 2011; 18 (6) :521-530
URL: http://jssu.ssu.ac.ir/article-1-1330-en.html

Abstract:   (6810 Views)
Introduction: Macromycetes are considered as new resources for medicine with various biological properties. One of the most important medicinal fungi in Iran is Phellinus conchatus. This genus contains 359 species around the world of which 12 species are reported from the north regions of Iran. Phellinus species have anticancer, antioxidant and antibacterial effects. Moreover, they have been used in traditional medicines for treatment of several diseases. Due to the increasing bacterial resistance to existing antibiotics, it seems that research for new sources of antibiotics is necessary. Methods: The purpose of this research was to collect and identify the species with respect to hosts, dispersal, macromorphological and micromorphological characters of the species, and their biological effect against Gram-negative bacteria and Gram-positive bacteria was evaluated using total methanol extract and it’s fractional extracts(chloroform, butanol and water extracts) using disk diffusion method, minimum inhibitory concentrations(MICs) and minimal bactericidal concentrations(MBCs). Results: The results of disk diffusion tests showed that all extracts except aqueous extract had growth inhibitory effects on three bacteria Staphylococcus aureus, Bacillus cereus and Pseudomonas aeruginosa. The butanolic extract showed the best result in growth inhibition against the bacteria, especially on Pseudomonas aeruginosa . The MICs and MBCs of the butanol extract of these bacteria were(1, 2mg.disk), (2, 4 mg.disk) and(8, 16mg.disk), respectively. Conclusion: The results show that different extracts, especially butanol extract have high antibacterial activities which indicate the presence of active components in this fraction. More fractionation studies are under way to isolate the antibacterial components in the butanolic extract.
Full-Text [PDF 930 kb]   (2948 Downloads)    
Type of Study: Original article | Subject: General
Received: 2011/01/24

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | SSU_Journals

Designed & Developed by : Yektaweb