Evaluation of severity of preeclampsia with mother’s serum high sensitive C-reactive protein (Hs-CRP)

Samiee Rad , Fatemeh; Jahani Hashemi , Hassan; Sofiabadi , Mohammad; Bahrami , Hamidreza

Volume 25, Issue 7 (oct 2017) JSSU 2017, 25(7): 556-563 | Back to browse issues page

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Samiee Rad F, Jahani Hashemi H, Sofiabadi M, Bahrami H. Evaluation of severity of preeclampsia with mother’s serum high sensitive C-reactive protein (Hs-CRP) . JSSU 2017; 25 (7) :556-563
URL: http://jssu.ssu.ac.ir/article-1-4122-en.html

Evaluation of severity of preeclampsia with mother’s serum high sensitive C-reactive protein (Hs-CRP)

Fatemeh Samiee Rad

, Hassan Jahani Hashemi

, Mohammad Sofiabadi ^*

, Hamidreza Bahrami

Abstract: (4882 Views)

Introduction: Preeclampsia is one of the most common complications in pregnancy and a main cause of death in the perinatal period. The early diagnosis of severe disease form is important. The aim of this study was to evaluate the relationship between the serum high sensitive C - reactive protein (hs-CRP) and severity of preeclampsia.
Methods: This cross-sectional study conducted between 2013 October -2014 February in third trimester pregnant women that had been admitted to Qazvin Kosar Hospital they were divided into three groups as: the first included 50 healthy pregnant women (control), the second included 45 women with mild preeclampsia and the third group included 42 women with severe pre-eclampsia. Blood pressure was measured after at least 10 minutes resting in a sitting position. Blood samples were taken six hours after admission and the hs-CRP measured by immunoturbidometric method using bionic kit. Data were analyzed using ANOVA, x²and Kruskal-Wallis tests.
Results: The average serum levels of hs-CRP were 2.4 in the control, 8.7 in the mild and 32.6 in the severe preeclampsia groups and this difference were significant in all the three groups.
Conclusion: According to the results, it seems that the serum levels of hs-CRP can be used in the prediction and diagnosis of the severity of preeclampsia.

Keywords: C - reactive protein, Preeclampisa, Pregnancy

Full-Text [PDF 1041 kb] (2169 Downloads)

Type of Study: Original article | Subject: Obstetrics
Received: 2017/02/20 | Accepted: 2017/07/29 | Published: 2017/11/15

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