The Journal of Shahid Sadoughi University of Medical Sciences
مجله علمي پژوهشي دانشگاه علوم پزشكي شهید صدوقی يزد
JSSU
Medical Sciences
http://jssu.ssu.ac.ir
20
journal20
2228-5741
2228-5733
fa
jalali
1404
12
1
gregorian
2026
3
1
33
11
online
1
fulltext
fa
بررسی ارتباط ویژگیهای دموگرافیک مادران باردار با کانونهای اکوژنیک داخل قلب جنین: یک مطالعه گذشتهنگر
Investigating the Association Between Demographic Characteristics of Pregnant Mothers and Fetal Intracardiac Echogenic Foci: A Retrospective Study
اطفال
Pediatrics
پژوهشي
Original article
<div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span aptos="" style="font-family:"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">مقدمه:</span></b> <span b="" lang="FA" nazanin="" style="font-family:">کانون اکوژنیک داخل قلب (</span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">EIF</span></span><span b="" lang="FA" nazanin="" style="font-family:">) به عنوان یک ساختار روشن کوچک در قلب جنین با اکوژنیسیته مشابه یا بیشتر به استخوان اطراف تعریف میشود که بهعنوان یک نشانگر در سه ماهه دوم بارداری مرتبط با آنوپلوئیدی در جمعیتهای پرخطر درنظر گرفته میشود. در این مطالعه، به بررسی ارتباط اندازه </span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Nuchal Translucency</span></span> <span b="" lang="FA" nazanin="" style="font-family:">(</span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">NT</span></span> <span b="" lang="FA" nazanin="" style="font-family:">) با یافتههای دموگرافیک مادران باردار در جنینهای دارای کانون اکوژنیک داخل قلب پرداخته شد.</span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span aptos="" style="font-family:"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">روش بررسی:</span></b> <span b="" lang="FA" nazanin="" style="font-family:">در این مطالعه گذشتهنگر مقطعی ، 100 پرونده بالینی از زنان باردار که دارای جنین با کانون اکوژنیک داخل قلب تائید شده از طریق اکوکاردیوگرافی بودند، مورد بررسی قرار گرفت. مشخصات دموگرافیک، بیماری زمینه ای مادر و همچنین </span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">NT</span></span> <span b="" lang="FA" nazanin="" style="font-family:">ثبت شد. برای بررسی ارتباط بین متغیرها از آزمون همبستگی پیرسون بهرهگرفته شد که با استفاده از نرم</span><span dir="LTR" lang="X-NONE" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""></span></span><span b="" lang="FA" nazanin="" style="font-family:">افزار </span><span dir="LTR" lang="X-NONE" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">SPSS</span></span><span b="" lang="FA" nazanin="" style="font-family:"> نسخه ۱۶ انجام شد.</span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span aptos="" style="font-family:"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">نتایج: </span></b><span b="" lang="FA" nazanin="" style="font-family:">براساس نتایج بدست آمده میانگین </span><span lang="FA" new="" roman="" style="font-family:" times="">±</span><span b="" lang="FA" nazanin="" style="font-family:"> انحراف معیار سن مادران و پدران در این مطالعه به ترتیب 6/449 </span><span lang="FA" new="" roman="" style="font-family:" times="">±</span><span b="" lang="FA" nazanin="" style="font-family:">29/90 و 19/056</span><span lang="FA" new="" roman="" style="font-family:" times="">±</span><span b="" lang="FA" nazanin="" style="font-family:">34/7 سال بود. وزن مادر نیز 10/037 </span><span lang="FA" new="" roman="" style="font-family:" times="">±</span><span b="" lang="FA" nazanin="" style="font-family:"> 75/810 کیلوگرم بود. همچنین۱۸</span><span lang="FA" new="" roman="" style="font-family:" times="">٪</span><span b="" lang="FA" nazanin="" style="font-family:"> زنان باردار مبتلا به دیابت و 6</span><span lang="FA" new="" roman="" style="font-family:" times="">٪</span><span b="" lang="FA" nazanin="" style="font-family:"> مبتلا به لوپوس بودند. میانگین عدد </span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">NT</span></span><span b="" lang="FA" nazanin="" style="font-family:"> نیز در جنینهای مورد بررسی 0/584 </span><span lang="FA" new="" roman="" style="font-family:" times="">±</span><span b="" lang="FA" nazanin="" style="font-family:"> 2/349 میلی متر بود و بین سن والدین و وزن مادر با عدد </span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">NT</span></span> <span b="" lang="FA" nazanin="" style="font-family:">ارتباط معنی داری وجود نداشت (</span><span dir="LTR" lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">P˃ 0.05</span></span><span b="" lang="FA" nazanin="" style="font-family:">).</span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span aptos="" style="font-family:"><b><span b="" lang="AR-SA" nazanin="" style="font-family:">نتیجهگیری:</span></b> <span b="" lang="FA" nazanin="" style="font-family:">این مطالعه نشان داد یافتههای دموگرافیک مادر با خطر آنوپلوئیدی در جنینهای دارای کانونهای اکوژن داخل قلب ارتباط معنیداری ندارد. در نتیجه، کانونهای داخل قلب اکوژنیک به عنوان یک نشانگر مجزا میتواند ابزاری برای شناسایی و نه حذف گروه پرخطر آنوپلوئیدی باشد.</span></span></span></span></span></span><br>
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<div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:18.0pt"><span aptos="" style="font-family:"><b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Introduction:</span></span></b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> Echogenic intracardiac focus (EIF) is defined as a small, bright structure within the fetal heart exhibiting echogenicity equal to or greater than that of the surrounding bone. It is considered a second-trimester soft marker associated with aneuploidy in high-risk populations. This study aimed to investigate the relationship between nuchal translucency (NT) thickness and maternal demographic characteristics in fetuses presenting with echogenic intracardiac focus.</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span aptos="" style="font-family:"><b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Methods:</span></span></b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> In this retrospective cross-sectional study, 100 clinical records of pregnant women whose fetuses had echogenic intracardiac focus confirmed by fetal echocardiography were reviewed. Maternal demographic characteristics, underlying maternal diseases, and NT measurements were recorded. Pearson correlation analysis was used to evaluate the associations between variables, and statistical analyses were performed using SPSS software version 16.</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span aptos="" style="font-family:"><b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Results:</span></span></b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> Based on the findings, the mean ± standard deviation of maternal and paternal ages were 29.90 ± 6.449 years and 34.19 ± 7.056 years, respectively. The mean maternal weight was 75.81 ± 10.037 kg. Additionally, 18% of the pregnant women had diabetes and 6% had lupus. The mean NT measurement among the evaluated fetuses was 2.349 ± 0.584 mm. No statistically significant association was observed between parental age or maternal weight and NT values (P > 0.05).</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:18.0pt"><span aptos="" style="font-family:"><b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></b><span lang="EN-GB" style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> The results of this study demonstrated that maternal demographic characteristics were not significantly associated with the risk of aneuploidy in fetuses with echogenic intracardiac focus. Therefore, echogenic intracardiac focus, as an isolated marker, may serve as a tool for identifying rather than excluding pregnancies at high risk for aneuploidy.</span></span><span dir="RTL" lang="AR-SA" style="font-size:11.0pt"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span><br>
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کانون اکوژنیک داخل قلب, اندازهگیری شفافیت نوکال, اطلاعات دموگرافیک مادر
Echogenic intracardiac focus, Nuchal translucency measurement, Maternal demographic information.
9592
9599
http://jssu.ssu.ac.ir/browse.php?a_code=A-10-5563-1&slc_lang=fa&sid=1
Soodeh
Hooshmandi
سوده
هوشمندی
s.Hooshmandi12@gmail.com