The Journal of Shahid Sadoughi University of Medical Sciences
مجله علمي پژوهشي دانشگاه علوم پزشكي شهید صدوقی يزد
JSSU
Medical Sciences
http://jssu.ssu.ac.ir
20
journal20
2228-5741
2228-5733
fa
jalali
1403
4
1
gregorian
2024
7
1
32
4
online
1
fulltext
fa
فراوانی کلونیزاسیون جدایههای استرپتوکوک گروه B در خانمهای باردار در ایران: مرور نظاممند و متاآنالیز
Prevalence of Group B Streptococcus Colonization in Pregnant Women in Iran: A Systematic Review and Meta-Analysis
میکروبیولوژی
Microbiology
مروری
Review article
<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مقدمه:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">استرپتوکوک گروه </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">B</span> <span dir="LTR" new="" roman="" style="font-family:" times="">(Group B Streptococcus; GBS)</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> یا استرپتوکوکوس آگالاکتیه </span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">یکی از عوامل اصلی عفونتهای تهاجمی نظیر مننژیت و سپتیسمی در نوزادان میباشد. کلونیزاسیون </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">GBS</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در ناحیه تناسلی، خطر زایمان زودرس را افزایش داده و نوزادان زودرس هم بیشتر در معرض خطر بیماری قرار دارند. اطلاعات اندکی در مورد میزان شیوع کلونیزاسیون رکتوواژینال </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">GBS</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در خانمهای باردار در ایران موجود است.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">روش بررسی:</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در مطالعه مروری حاضر، با جستجو در پایگاههای اطلاعاتی </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Pubmed, Google scholar, Scopus, Web of Science, SID</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> با استفاده از کلیدواژههای مرتبط و بدون محدودیت زمانی، مطالعات با بررسی عنوان و سپس چکیده مورد بررسی قرارگرفتند. دادهها با استفاده از با نرمافزار (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Comprehensive MetaAnalysis Biostat V3</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) بررسی شدند. ناهمگنی بین مطالعات با شاخص </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">I2</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> بررسی و بـر اساس نتایج ناهمگنی از مدل اثر تصادفی جهت تعیین شیوع استفاده </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">GBS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> شد.</span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتایج:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">از 231 مقاله یافت شده، 15 مقاله وارد مطالعه شدند. آنالیز 15 مطالعه نشان داد که شیوع </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">GBS</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در خانمهای باردار ایرانی </span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">(15/1- 9/9</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">CI 95%: </span><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) 12/2% </span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">است.</span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتیجهگیری:</span></span></b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> به منظور پیشگیری از بروز بیماری شدید در نوزادان، غربالگری تمام خانمهای باردار از نظر کلونیزاسیون </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">GBS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در هفتههای 35 تا 37 انجام گیرد. با توجه به نبود راهکارهای پیشگیرانهای برای جلوگیری از عفونتهای </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">GBS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در ایران، باید دستورالعملهای ملی برای راهنمایی متخصصان زنان و زایمان، ماماها و پرستاران در زمینه پیشگیری از عفونتهای </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">GBS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> تدوین گردد. </span></span></span></span></span></span></span><br>
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<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Introduction:</span></b> <span new="" roman="" style="font-family:" times="">Group B Streptococcus (GBS) or Streptococcus agalactiae is one of the main causes of invasive infections such as meningitis and septicemia in infants. Genital colonization with group B streptococci has been related to increased risk of premature delivery, and premature infants are at greater risk of disease. There is limited information about the prevalence of rectovaginal GBS colonization in pregnant women in Iran.</span><span new="" roman="" style="font-family:" times=""> The aim of the present study was investigating the prevalence of group B streptococcus colonization in pregnant women in Iran.</span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Methods:</span></b><span new="" roman="" style="font-family:" times=""> Information of this study was attained by searching on databases including PubMed, Google Scholar, Scopus, Web of Science and SID using relevant keywords and without time limit. Then, the studies containing the inclusion criteria were reviewed. The data were analyzed using Comprehensive MetaAnalysis software (Biostat V3). Heterogeneity between studies was investigated with the I2 index and based on the results of heterogeneity, the random effect model was implemented in order to determine the prevalence of GBS in pregnant women.</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Results:</span></b><b> </b><span new="" roman="" style="font-family:" times="">Out of 231 articles, 15 articles were included in the study. The analysis of 15 studies showed that the prevalence of GBS in Iranian pregnant women was 12.2% (95% CI: 9.9-15.1).</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Conclusion:</span></b><b> </b><span new="" roman="" style="font-family:" times="">In order to prevent the invasive neonatal disease, screening for GBS colonization is recommended for pregnant women in 35–37 weeks of gestation. Regarding the lack of preventive strategies for GBS infections in Iran, national guidelines should be established to guide the obstetricians, midwives, and nurses on the prevention of GBS infections</span><span new="" roman="" style="font-family:" times="">.</span></span></span></span><br>
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استرپتوکوکوس گروه B, خانمهای باردار, کلونیزاسیون, ایران
Group B Streptococcus, Colonization, Pregnant women, Iran.
7715
7723
http://jssu.ssu.ac.ir/browse.php?a_code=A-10-5226-1&slc_lang=fa&sid=1
Mahsa
Ghamari
مهسا
قمری
mahsa7477@yahoo.com