The Journal of Shahid Sadoughi University of Medical Sciences
مجله علمي پژوهشي دانشگاه علوم پزشكي شهید صدوقی يزد
JSSU
Medical Sciences
http://jssu.ssu.ac.ir
20
journal20
2228-5741
2228-5733
fa
jalali
1402
4
1
gregorian
2023
7
1
31
4
online
1
fulltext
fa
بررسی فاکتورهای آزمایشگاهی در بیماران مبتلا به کووید 19 در شهرهای یزد، میبد و اردکان در سال 1399
Evaluation of Laboratory Factors in Patients with Covid 19 in Yazd, Maybod, and Ardakan Cities in 2020
بیماری های عفونی
Infectious Diseases
پژوهشي
Original article
<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مقدمه:</span></span></b><b> </b><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">سازمان بهداشت جهانی</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> (</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""> WHO</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) این سندرم ویروسی جدید را به عنوان بیماری کروناویروس 2019 (</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">COVID-19</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) نامگذاری نمود. بعضی از پارامترهای آزمایشگاهی در بیماران مبتلا به کووید 19 تغییر مییابد. این مطالعه با هدف ارزیابی پارامترهای آزمایشگاهی در بیماران مبتلا به </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">COVID-19</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> انجام شد.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">روش بررسی:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مطالعه مقطعی-تحلیلی در بیمارستانهای شهید صدوقی یزد، امام جعفر صادق میبد و شهید ضیایی اردکان بین تاریخ فروردین و اردیبهشت 1399 انجام شد.</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">جامعه مورد مطالعه ما بیماران مبتلا به کووید 19 همراه با تست </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">PCR</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> مثبت بود که با روش نمونهگیری در دسترس 275 نفر وارد مطالعه شدند. چکلیست این مطالعه شامل اطلاعات دموگرافیک، اطلاعات بستری در بیمارستان و مقادیر آزمایشات: </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">CBC</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">diff</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">ESR, AST, ALT, Cr, Urea ,LDH, PT,PTT, INR</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> بود.</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">در نهایت داده</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">ها توسط نرمافزار</span></span><span dir="LTR" new="" roman="" style="font-family:" times="">SPSS version 16 </span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> مورد تحلیل قرار گرفت</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">و سطح معنی</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">داری کمتر از 0/05 در نظرگرفته شد.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتایج:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">بین مقادیر آزمایش</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">های </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">WBC, Lymphocyte, Neutrophil, ESR, Urea, Creatinine, LDH, AST</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> تفاوت معنی</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">داری در دو گروه فوت شده و بهبود یافته مشاهده شد.</span></span> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">در بین بیمارانی که در بخش</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">های معمولی، </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">ICU</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> و یا هردو بستری بودند، تفاوت معنی</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">داری بین بیماران بهبود یافته و فوت شده یافت شد <span style="letter-spacing:.1pt">(0/000</span></span></span><span dir="LTR" new="" roman="" style="font-family:" times=""><span style="letter-spacing:.1pt">P=</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:.1pt">)</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">. در بیماران فوت شده به طور معنی</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">داری تعداد روزهای بستری بیشتری و سنین بالاتری مشاهده شد<span style="letter-spacing:.1pt">(0/000</span></span></span><span dir="LTR" new="" roman="" style="font-family:" times=""><span style="letter-spacing:.1pt">P=</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"><span style="letter-spacing:.1pt">)</span></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> .</span></span> <span dir="LTR" style="font-size:10.0pt"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتیجهگیری:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">در مطالعه حاضر به این نتیجه رسیدیم علاوه بر افزایش سطح </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">WBC</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">، نوتروفیل، اوره، کراتینین،</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""> LDH </span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> و </span></span><span dir="LTR" new="" roman="" style="font-family:" times="">AST</span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در بیماران فوت شده، کاهش لنفوسیت نیز مشاهده شده است و از این نتایج میتوان در بحران</span></span><span dir="LTR" new="" roman="" style="font-family:" times=""></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">های آینده کووید19 بهره گرفت.</span></span><span lang="FA" style="font-size:12.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span><br>
</div>
<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Introduction:</span></b> <span new="" roman="" style="font-family:" times="">This new viral syndrome named as Coronavirus disease 2019 (COVID-19) by WHO. Some laboratory parameters change in the patients with covid-19. This study was conducted with the aim of evaluating laboratory parameters in the patients with COVID-19.</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Methods:</span></b><span new="" roman="" style="font-family:" times=""> A cross-sectional-analytical study was conducted in the hospitals of Shahid Sadoughi of Yazd, Imam Jafar Sadegh of Meibod and Shahid Ziaei of Ardakan between April and May 2019. The study population was patients with Covid-19 with a positive PCR test, 275 people were included in the study using the available sampling method. The checklist of this study included demographic information, hospitalization information and test values (CBC, diff, ESR, AST, ALT, Cr, Urea, LDH, PT, PTT, INR). Data were analyzed by SPSS software version 17 and the significance level was considered less than 0.05.</span> <span style="font-family:"Times New Roman",serif"></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Results:</span></b><b> </b><span new="" roman="" style="font-family:" times="">A significant difference was observed between the values of WBC, Lymphocyte, Neutrophil, ESR, Urea, Creatinine, LDH, AST tests in the two groups that died and recovered. </span><span new="" roman="" style="font-family:" times="">Among the patients who were hospitalized in the general departments, ICU or both, a significant difference was found between the patients who recovered and those who died (<i>P=</i>0.000). Significantly, more number of hospitalization days and older age were observed in deceased patients (<i>P=</i>0.000).</span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Conclusion:</span></b><b> </b><span new="" roman="" style="font-family:" times="">In the present study, we came to the conclusion that in addition to increasing the level of WBC, neutrophil, urea, creatinine, LDH and AST in deceased patients, a decrease in lymphocytes was also observed and these results can be used in future crises of Covid-19.</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br>
</div>
کووید19, بهبودی, WBC , آزمایش
COVID19, Recovery, WBC, Test.
6591
6600
http://jssu.ssu.ac.ir/browse.php?a_code=A-10-5021-1&slc_lang=fa&sid=1
Hadi
Zare Mehrjardi
هادی
زارع مهرجردی
hadizare1387@gmail.com