fa بررسی یافته‌های تصویربردای رزونانس مغناطیسی مغز در بیماران مراجعه‌کننده با تشنج بیماریهای مغز و اعصاب Neurology پژوهشي Original article <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مقدمه:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">تشنج یکی از علائم شایع و هشداردهنده بیماری‌های مغز می‌باشد که پزشکان اغلب برای تشخیص از </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">CT-scan</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> یا </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> مغز استفاده می‌کنند. مطالعه حاضر با هدف بررسی </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Brain MRI</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> بیماران مراجعه‌کننده با تشنج به منظور تعیین ضایعات و درگیری‌های مغزی آنان انجام گردید.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">روش بررسی:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مطالعه به روش مقطعی-توصیفی گذشته‌نگر انجام شد. کلیه بیماران مراجعه‌کننده با تشنج جهت انجام </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> به بخش رادیولوژی بیمارستان شهید صدوقی یزد طی سال‌های 1400-1395 بررسی شدند. با مراجعه به بایگانی بخش رادیولوژی، پرونده و </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> بیماران مراجعه‌کننده با تشنج استخراج شدند. سپس داده‌ها از سیستم </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">HIS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> و پرونده بیماران استخراج و به کمک نرم‌افزار </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">version 16</span></span> <span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">SPSS</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> تجزیه و تحلیل شد.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتایج:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">مطالعه حاضر بر روی 105 بیمار مراجعه‌کننده با تشنج جهت انجام تصویربردای مغز انجام گردید. 48/6 درصد (51 نفر) از بیماران مرد و 51/4 درصد (54 نفر) خانم بودند. میانگین سنی بیماران، 10/50 </span></span><span lang="FA" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">&plusmn;</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> 34/17 سال بود. </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> 56 درصد از بیماران نرمال بود. 16/2 درصد غیراختصاصی (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Non Specefic</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">)، 7/6 درصد توده (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Mass</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) و 4/8 درصد از بیماران نیز شواهدی از نرم‌شدگی مغزی (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Encephalomalacia</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) گزارش گردید. بیشترین ضایعات با 10/5 درصد مربوط به لوب فرونتال چپ و 2/9 درصد مربوط به لوب فرونتال سمت راست بود. 99 درصد از تشنج‌ها از نوع تشنج غیراختصاصی (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Unspecified Convulsion</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) و 1 درصد از نوع تشنج پس از عمل جراحی (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">PostProcedural Disorder Of Nervous System</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) بود. بین جنسیت بیماران و تشخیص آن‌ها نیز ارتباط معنی‌داری مشاهده نگردید (0/471 </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">P></span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">).</span></span> <span dir="LTR" style="font-size:10.0pt"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:18.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span lang="AR-SA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">نتیجه‌گیری:</span></span></b> <span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">ناهنجاری‌های گسترده‌ای ازجمله وجود توده (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Mass</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">)، تخریب میلین (</span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Demylination</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:">) و نرم‌شدگی مغزی و در </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span lang="FA" style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> در بیماران مبتلا به تشنج مشاهده می‌گردد و اغلب در لوب فرونتال قرار دارند. در مجموع، تشنج می‌تواند سبب ناهنجاری‌های مغزی زودگذر و برگشت‌پذیر در </span></span><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">MRI</span></span><span style="font-size:12.0pt"><span b="" nazanin="" style="font-family:"> بگردد.</span></span></span></span></span></span></span><br> &nbsp;</div> <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Introduction:</span></b> <span new="" roman="" style="font-family:" times="">Seizures are one of the common and warning signs of brain diseases, which doctors often use CT-scan or MRI for diagnose. The present study was conducted with the aim of evaluation of brain MRI of the patients referred with seizures in order to determine their brain lesions and involvement.</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Methods:</span></b><span new="" roman="" style="font-family:" times=""> The study was carried out using a retrospective cross-sectional descriptive method. All the patients with seizures referred for MRI to the Radiology Department of Shahid Sadoughi Hospital in Yazd City, Iran during 2016-2020 were examined. By referring to the archives of the radiology department, the records and MRI of the patients referred with seizures were extracted. Then, the data were extracted from the Hospital Information System</span> <span new="" roman="" style="font-family:" times="">and the patients&#39; files; after that they were analyzed with SPSS version 16.</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:18.0pt"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Results:</span></b><b> </b><span new="" roman="" style="font-family:" times="">The present study was conducted on 105 patients with seizures for brain MRI. 48.6% (51</span><span new="" roman="" style="font-family:" times=""> people</span><span new="" roman="" style="font-family:" times="">) of patients were male and 51.4% (54 people) were female. The average age of the patients was 34.17 &plusmn; 10.50 years. MRI was normal in 59% of the patients. 16.2% Non-Specific, 6.7% Mass and 4.8% evidence of Encephalomalacia were also reported. The most lesions with 10.5% were related to left frontal lobe and 2.9% were related to right frontal lobe. 99% of seizures were unspecified convulsion and 1% were postprocedural disorder of nervous system. There was no significant relationship between the gender of the patients and their diagnosis (P>0.471).</span><span style="font-family:"Times New Roman",serif"></span></span></span></span><br> <b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span> </b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Wide abnormalities such as mass, edema, encephalomalacia and demyelination are observed in the MRI of the patients with seizures and are often located in the frontal lobe. In general, seizures can cause transient and reversible brain abnormalities in MRI</span></span></div> تشنج, صرع, مغز, MRI Seizures, Epilepsy, Brain, MRI. 7255 7263 http://jssu.ssu.ac.ir/browse.php?a_code=A-10-5027-1&slc_lang=fa&sid=1 Moein Ahmadi Bani معین احمدی بنی moeinahmadi1211@gmail.com 0000-0003-2725-2964 Yes Department of Radiology, Medicine Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. گروه رادیولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی شهید صدوقی، یزد، ایران. Amir Pasha Amel Shahbaz امیرپاشا عامل شهباز pasha.shahbaz@gmail.com 0000-0003-2673-0135 No Student Research Committee, Medicine Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. کمیته تحقیقات دانشجوئی، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات درمانی شهید صدوقی، یزد، ایران.