Recombinant probiotic-Based Vaccines; Attractive vehicles for immunization via mucosal routes

Nabizadeh, Seyyed Fatemeh; Dehqan, Fatemeh; Khashei Varnamkhasti, Khalil

doi:10.18502/ssu.v30i4.9891

Volume 30, Issue 4 (7-2022) JSSU 2022, 30(4): 4702-4705 | Back to browse issues page

‎ 10.18502/ssu.v30i4.9891

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Nabizadeh S F, Dehqan F, Khashei Varnamkhasti K. Recombinant probiotic-Based Vaccines; Attractive vehicles for immunization via mucosal routes. JSSU 2022; 30 (4) :4702-4705
URL: http://jssu.ssu.ac.ir/article-1-5730-en.html

Recombinant probiotic-Based Vaccines; Attractive vehicles for immunization via mucosal routes

Seyyed Fatemeh Nabizadeh

, Fatemeh Dehqan

, Khalil Khashei Varnamkhasti ^*

Abstract: (814 Views)

Introduction: The importance of genetically modified microorganisms, including probiotics, now widely have considered as attractive vehicles for mucosal delivery of therapeutic molecules. Previous studies have indicated that mucosal administration of these molecules can effectively trigger humoral along with cellular immune responses. Therefore, development of induction of mucosal immune responses, utilizing of recombinant probiotics-based vaccines, as live delivery vectors with no side effects in humans, may contribute to effectiveness of control strategies against infection agents.

Keywords: Vaccine, Recombinant probiotic, Mucosal immunization

Full-Text [PDF 367 kb] (360 Downloads)

Type of Study: Letter to editor | Subject: Immunology
Received: 2022/05/1 | Accepted: 2022/06/8 | Published: 2022/07/6