Introduction: Despite advances in the recognition of new risk factors, prevention, diagnosis and treatment, cancer is still remains as a global health problem. Several numbers of studies have recently provided evidence that because of having pro apoptotic effects, biotoxins such as bacterial toxins, could be used as potential antitumor agents. Staphylococcus aureus, as a major human pathogen, has various toxins, such as enterotoxin superfamily that causes apoptosis during infection. Therefore, it seems that there is a good research field for the use of this toxin in the control and treatment of malignancies.

Keywords: Staphylococcus aureus, Bacterial toxins, Enterotoxin, Biotoxins, Apoptosis, Cancer.

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