Introdution: Mucormycosis is recognized as an invasive fungal infection with a high mortality rate, which typically affects patients with uncontrolled diabetes. As a matter of fact,  immunocompromised patients are at risk of this disease. Aim of this study was presentation of denture and orbital prosthesis construction for a paitient with mucormycosis.
Case report: A 73 year-old woman with pain, inflammation and numbness of the left buccal referred to Shahid Sadoughi Hospital of Yazd. Lab tests revealed an uncontrolled diabetes mellitus.  Mucormycosis was diagnosed via the patient’s oral Biopsy. Foci of fungal necrosis in the palate and maxillary sinus was removed. Then, the patient was referred to the Department of Prosthodontics of  Dentistry School of  Shahid Sadoughi University.
Conclusion: Early diagnosis of mucormycosis could increase the patients’ survival rate.Therefore, dentists can play an important role in primary diagnosis of the lesion, because rapid treatment of the disease can prevent of the progression of it. Rehabilitation of the patients’ appearance seems to be necessary in order to eliminate the facial defects after the surgery. As a result, maxillofacial prosthetics plays an important role in restoring the patient’s appearance.

Keywords: Fungal infections, Maxillofacial prosthesis, Mucormycosis.

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