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Introduction: Exercise is a factor that influences endocrine system. Effect of exhaustive exercise in the hypothalamus is still vague and changes in hormones are dependent on the extent, duration, type, and previous exercises. Methods: In this experimental study, 14 volunteered runners participated. All subjects ran on a treadmill until they reached the endurance level and then blood samples were obtained in three phases (before, immediately after, and 10 minutes after exercise). The data was analyzed by ANOVA. All the results below P value of 0.05 (P < 0.05) were considered to be significant. Results: Mean and standard deviation of testosterone in three phases of before, immediately after, and 10 minutes after exercise were respectively 10.6±1.25, 10.62±2.82, and 10.64±2.57. Moreover, regarding progesterone, measures were 0.61±0.41, 0.99±0.53, and 1.08±0.44. Therefore there was no significant difference between testosterone level before exercise with immediate, and 10 minutes after exercise, but progesterone level revealed a significant difference among before, immediately, and 10 minutes after exercise. Conclusion: Results showed that one session of exhausting exercise could not significantly change testosterone level, whereas increases progesterone level significantly.

Keywords: Athletes; Exhausting Exercise; Hormonal level; Progesterone; Testosterone

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