Showing 6 results for Hoori
F Heshmati, H Noroozinia , R Abbasivash, Ar Mahoori, M Andaroodi,
Volume 14, Issue 3 (Autumn 2007 2006)
Abstract
Introduction: Postoperative pain is an acute pain related to size and site of operation, patient's psychologic and physiological condition, degree of manipulation and damage of tissues. Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Administration of opioids is one of the common techniques for postoperative pain management, but complications related to opioids leads to use of other methods for pain control. In this study we evaluated the effect of low dose lidocaine infusion for postoperative pain control.
Methods: In this study, 30 patients were randomized in two study and control groups under similar conditions. In study group, administration of lidocaine 1% (1.5mg/kg followed by 1.5 mg/ kg /h infusion) was started 30 minutes before operation, and continued 1hour after operation. In control group, normal saline (placebo) was used. After 24hours, pain of patients and systemic analgesic consumption was assessed and analyzed.
Results: Results showed that infusion of low dose lidocaine does not reduce postoperative pain and amount of morphine consumption 24hours after operation.
Conclusion: Difference in results of this study and other similar investigations can result from difference in design and selected surgical procedures. Also, lack of medical and research equipments such as appropriate PCA (Patient Controlled Analgesia) and measurement of blood levels of lidocaine were limitations of this study.
H Noroozinia, F Heshmati, A Hassani Afshar, Ar Mahoori, E Hassani, F Omidi,
Volume 16, Issue 2 (Summer 2008)
Abstract
Introduction: Hearing loss after surgery is reported rarely. Its prevalence rate is different and reported to be between 3-92%. Hearing loss is often subclinical and not diagnosed without audiometry. The aim of this study was to determine rate of hearing changes after spinal anesthesia in patients undergoing surgery with spinal anesthesia.
Methods: In this descriptive study, forty male patients scheduled for repair of inguinal hernia under spinal anesthesia were selected by simple sampling method. Before surgery, audiometry was performed for both the ears of the patients. Audiomatery was performed again by the audiometry specialist on day one, five, fifteen and two months after surgery.
Results: Hearing loss was observed in 13 (32.5%) patients. Hearing loss in 12 patients (92%) was in low hearing frequency range and 1 patient (8%) was in mid hearing frequency. Hearing loss in 8 patients (61%) was ipsilateral and in 5 patients (39%) was bilateral. Hearing loss in 9 patients (69%) on 5th day and 2 patients (5/15%) on 15th day resolved spontaneously.
Conclusion: Results of this study conformed that hearing loss after spinal anesthesia is not a serious problem and can resolve spontaneously. It seems that there is relationship between hearing loss and headache.
F Haghirossadat, F Bernard, M Kalantar, Mh Sheikhha, F Hokmollahi, M Azimzadeh, M Hoori,
Volume 18, Issue 3 (Aug/Sep 2010)
Abstract
Introduction: Medicinal plants are valuable natural resources that are nowadays known as safe pre-materials for drug industries in the advanced countries. Black caraway is one of the most important and economical medicinal plants that can be grown naturally in some regions of Yazd province. The essence of the plant are used in treatment of diarrhea, dyspepsia, fever, flatulence, stomachache, hemorrhoids, hiccoughs, as an antihistaminic and more numerous uses in medicine industries. This plant shows several therapeutic effects on digestive and urinary tract disorders and is well known as an anti-convulsant, anthelmintic, anti-asthma and antidyspnic drug in Iranian traditional medicine. Bunium Persicum oil is capable of suppressing the initial stage of an inflammatory process. Also, this plant is used for culinary purposes and for flavoring foods and beverages.
Methods: In this research, the fractionization of seed essence was done by GC method and the compounds were recognized. The DPPH test was used for estimating anti oxidant effects and the Follin-Ciocalteu method was used for estimating quantity of phenol compounds.
Results: The results revealed that- γTerpinene had the highest percentage in the essence of the native black caraway of Yazd province. Also, the antioxidant test showed the high antioxidant effect of the native black caraway of Yazd province with an IC50 of 2.85 µg.mg-1 and the phenolic component percentage of 117.09mg.g1.
Conclusion: This result was much higher than previous similar studies about black caraway.
M Kaviani, M Ashoori, S Azima, Ar Rajaei Fard , Mj Hadian Fard ,
Volume 20, Issue 2 (May-Jun 2012)
Abstract
Introduction: Delivery is one of the most painful experiences to women throughout life therefore, it seems essential to obtain remedies for labor pain relief, especially in regard to non-invasive methods. This study intends to compare effect of two methods of acupressure and ice massage on the pain severity, anxiety level and length of labor in nulliparous women
Methods: In this experimental study, 165 nulliparous women were randomly assigned to three groups. First group: acupressure, Group II: ice massage, and group III: control. Each group consisted of 55 women. Intervention was exerted in cervical dilatation of 3-4 cm on LI-4 and intervention period lasted for 30 minutes. In the first group pressure and in the second group ice massage was applied. Labor pain and anxiety levels in the three groups were assessed by VAS and Spielberger state questionnaire in two stages. Duration of first and second stage of labor was compared in the three groups.
Results: There was a significant decrease in pain immediately after intervention in ice massage and acupressure groups in comparison to the control group (P≤0/001). Moreover, pain was decreased more in the ice massage group, whereas pain intensity was increased in the control group (P≤0/001). Anxiety level and the length of first and second stage of labor were significantly reduced (P≤0/001) in comparison with the control group.
Conclusion: Both acupressure and ice massage lead to reduce pain intensity, duration of labor and level anxiety in nulliparous women, the ice massage appeared to be more influential
Sadra Amirpour Haradasht, Solmaz Akbari, Mehrfam Khoshkhounejad, Hoori Aslroosta,
Volume 31, Issue 1 (4-2023)
Abstract
Introduction: This prospective analytical study was conducted with the aim of determining the prevalence, severity and factors affecting the short-term complications of implant surgery.
Methods: In a descriptive cross sectional study, patients referring to the implant department of Tehran University of Medical Science from 2020 to 2021 were included (292 implants in 152 patients). Patients underwent Simple implant placement without hard and/or soft tissue grafts were included. After 7 and 14 days, ecchymosis, bleeding, swelling, delayed wound healing, infection, and trismus were recorded. Pain, the most common outcome after surgeries was assessed based on the number of days the patient had pain, the number of analgesics used and the severity of pain (Numeric pain intensity scale) using SPSS software version 16. The relationship between complications and measured variables was examined by logestic regression analyses.
Results: The most common complications on the 7th day follow up were ecchymosis (3.9%) and delayed wound healing (3.9%). The mean pain score was 1.61 ± 1.32. No patient had pain more than 3 days after surgery. The mean number of analgesic used was 2.23 ± 1.82. Based on logistic regression analyses, only patient age and the number of days of analgesics use showed a significant relationship with the number of analgesics used (P˂0.001). Neither the level of expertise of the surgeon nor the patients' gender had nosignificant effect on the degree of complications pain and amount of patient pain and the consumption of analgesics (P˃0.05). Patients with poor oral hygiene used more analgesics in comparison to patients with favorable oral hygiene.
Conclusion: The overall prevalence of post-operative complications after simple implant surgeries was less than 4%. The older the patient, the higher the consumption of analgesics.
Mohammad Reza Royaei, Mohammad Taher Tahoori,
Volume 32, Issue 1 (4-2024)
Abstract
Introduction: Fibroblast-like synoviocytes (FLS), also known as synovial fibroblasts or type B synoviocytes, are the primary cells responsible for the structure of the synovial lining. They are crucial for the formation of a healthy, organized synovial lining. In rheumatic synovium affected by inflammation, the typical three-layered synovial lining transforms into a pannus-like structure. Various pro-inflammatory conditions in the joints of rheumatoid arthritis (RA) patients, characterized by elevated levels of cytokines, growth factors, and infiltration of inflammatory cells, strongly activate FLS cells. Moreover, environmental conditions in the joints of RA patients, such as high pressure and hypoxia, induce changes that further contribute to FLS activation and the development of aggressive characteristics. These changes include increased proliferation, reduced apoptosis, and enhanced cell migration, collectively referred to as a tumor-like phenotype. Additionally, FLS cells release inflammatory cytokines, amplifying inflammation and attracting immune cells to the joint. They also play a role in degrading the extracellular matrix and causing cartilage and bone damage through the production of enzymes like matrix metalloproteinases (MMPs), collagenase, aggrecans, and cathepsins. Recent therapeutic approaches have been directed at targeting the signaling pathways that activate FLS cells and inhibiting factors and cytokines produced by these cells to alleviate inflammatory symptoms and reduce joint damage. It is anticipated that these treatment strategies will complement existing therapies in the near future.
Conclusion: FLS cells are the main components of maintaining the health and nutrition of joints. These cells produce various cytokines, chemokines, angiogenic factors, as well as factors that contribute to the breakdown of matrix and cartilage. The main drivers of significant changes in inflamed joints are proliferation and resistance to apoptosis. Treatment strategies have been developed to target the signaling pathways that activate these cells, with a focus on improving inflammatory symptoms. It is expected that these treatment strategies will be incorporated into existing therapies in the near future.
