Introduction: Post operative pain is an unpleasant experience following various stimuli resulting in a response by the body. This process causes physiological disturbances in all of the systems of the body. Methods and Materials: In this clinical trial , 60 upper abdominal surgery patients were selected post operatively and divided into two groups of 30 patients each. In one group, bupivacaine intrapleural injection and in the other group, opioid injections were administered in the recovery room. Pain intensity with visual analogous scale was measured 6 hours after the operation. Results: There was no difference in VAS according to patient's age, sex, and type of operation, but in the Bupivacaine injected group, VAS score was significantly lower. Conclusion: Intrapleural injection of bupivacaine is more useful and reliable than opioids for controlling post operative pain.

Keywords: Bupivacaine, Postoperative Pain, Intrapleural Analgesia

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