Introdution: One of the most important signs of general health is oral health. Many systemic diseases have oral manifestations that could be appeared in the oral cavity at first. Therefore, considering the importance of timely diagnosis and treatment of oral lesions. This study was conducted to determine the prevalence of oral lesions in the patients admitted to Yazd ShahidSadoughi Hospital.
Methods: In this cross sectional study, 443 hospitalized patients were clinically evaluated for oral mucosal lesions. All of the abnormal variations in oral mucosa in these patients, demographic data, type & location of oral lesion, existence of denture & smoking were documented. Data were analyzed by SPSS Inc., Chicago, IL; Version 19 was analyzed using Chi-square and Fisher exact tests.
Results: Oral lesions were observed in 37.7% of patients. The most common type of lesion was related to red and white lesions, which was seen in 19.1% of patients.  Palate was the common location for red and white lesions. Most of vesiculobollous lesions were observed in the hard palate and tongue. The lesions rate increased with aging. Among the lesions, only pigmented lesions were significantly higher in males.
Conclusion: Regarding the high prevalence of oral mucosal lesions in admitted patients, the importance of more attention to oral cavity for timely diagnosis and referral in the routine examination is emphasized.