A Survey on Leptospirosis in Persons Referred to  Shahid Beheshti Hospital in Astara

Noorimanesh , S; Shafighi , T; Abdollahpour , Gh

Volume 24, Issue 5 (Aug 2016) JSSU 2016, 24(5): 366-374 | Back to browse issues page

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Noorimanesh S, Shafighi T, Abdollahpour G. A Survey on Leptospirosis in Persons Referred to Shahid Beheshti Hospital in Astara . JSSU 2016; 24 (5) :366-374
URL: http://jssu.ssu.ac.ir/article-1-3720-en.html

A Survey on Leptospirosis in Persons Referred to Shahid Beheshti Hospital in Astara

S Noorimanesh

, T Shafighi ^*

, Gh Abdollahpour

Abstract: (6244 Views)

Introduction: Leptospirosis is a bacterial and zoonotic disease caused by Leptospira species. Gilan province is an endemic region for this disease due to its humid climate with heavy rainfall. The aim of this study was serological diagnosis of leptospirosis in persons referred to Astara central laboratory .

Methods: A descriptive, cross-sectional study of human leptospirosis was conducted during February-May 2015, 98 random serum samples were collected from persons referred to Astara central laboratory of Shahid Beheshti Hospital. All serum samples were serologically tested by Microscopic Agglutination Test (MAT) using live antigens representing Leptospira interrogans serrovars: Gripotyphosa, Icterohaemorrhagiae, Canicola, Hardjo and Pomona.

Results: The result of this study showed that the rate of positive reaction against serovar, positive MAT was found in rural housewives between 60 and 69 years old and the highest serological titre was measured to be1:200.

Conclusion: It was concluded that the low prevalence of Leptospira.spp in Astara city could be attributed to the increased awareness of transmission routes of this disease, improved hygiene and sanitation practices, avoidance of contaminated water and mechanization of farming.

Keywords: Leptospirosis, Agglutination Test

Full-Text [PDF 498 kb] (2400 Downloads)

Type of Study: Original article | Subject: Microbiology
Received: 2016/05/9 | Accepted: 2016/08/6 | Published: 2016/10/2

References

1. Romero-Vivas CM, Cuello-Pérez M, Agudelo-Flórez P, Thiry D, Levett PN, Falconar AK. Cross-Sectional Study of Leptospira Seroprevalence in Humans, Rats, Mice, and Dogs in a Main Tropical Sea-Port City. Am J Trop Med Hyg 2013; 88(1): 178-83.

2. Abdollahpour G, Shafighi TS, Sattari Tabrizi, S. Serodiagnosis of leptospirosis in cattle in north of Iran, Gilan. Int J Vet Res 2009; 3(1): 7-10.

3. Ahmed N, Devi SM, De los A Valverde M, Vijayachari P, Machang'u RS, et al. Multilocus sequence typing method for identification and genotypic classification of pathogenic Leptospira species. Ann Clin Microbiol Antimicrob 2006; 5(1): 28.

4. Halliday JE, Knobel DL, Allan KJ, Bronsvoort BMDC, Handel I, Agwanda B, et al. Urban Leptospirosis in Africa: A Cross-Sectional Survey of Leptospira Infection in Rodents in the Kibera Urban Settlement, Nairobi, Kenya. Am J Trop Med Hyg 2013; 89(6): 1095-102.

5. Ghane M, Yasouri SR. Isolation and identification of pathogenic and saprophytic Leptospira spp.from the rice fields of Tonekabon Township using culture and PCR technique. Ann Biol Res 2014; 4(11): 123-28.

6. Tabatabaei HA, Firoozi R. Diseases of animals due to bacteria. Tehran Univ press 2002; 1: 431. [Persian]

7. Issazadeh K, Amirmozaffari N, Mehrabian S, Oryan S. American-Eurasian. J Sci Res 2008; 3(2): 147-52.

8. Goris MG, Hartskeerl RA. Leptospirosis serodiagnosis by the microscopic agglutination test. Curr Protoc Microbio 2013; 12E-5.

9. World Health Organization. Human leptospirosis : guidance for diagnosis, surveillance and control. 2003

10. Honarmand H, Eshraghi S, khormizadeh MR, Hareskeerl RA, Ghanati FM, Abdolahpour MR. et al. Distribution of human leptospirosis in Guilan province,Northern Iran. J public Health 2007; 36(1): 68-72.

11. Shafighi T, Abdollahpour G, Zahraei Salehi T, Tadjbakhsh H. Serological and bacteriological study of leptospirosis in slaughtered cattle in north of Iran (Rasht). A JMR 2010; 4(20): 2118-21.

12. Honarmand H, Rasaei H, Rezvani M, Hoseini S, Rahbare Taramsari M. A survey on leptospirosis in Guilan province a 10-year study(1999- 2008). Iranian J Infectious Dis 2009; 4(47): 47-53. [Persian]

13. Mansour-Ghanaaei F, Honarmand H. Leptospirosis & leptospirosis in Guilan, Iran. Farhange ilia press 2006; 1: 96-9. [Persian]

14. Zakeri S, Khorami N, Ganji ZF, Sepahian N, Malmasi AA, Gouya MM, et al. Leptospira wolffii, a potential new pathogenic Leptospira specie detected in human, sheep and dog. Infection, Genetics and Evolution 2010; 10(2): 273-77.