Volume 24, Issue 4 (Jul 2016)                   JSSU 2016, 24(4): 317-328 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

baharara J, motie M, ramezani T, iranbakhsh A. synergic application effects of silver nanoparticles and low-frequency electromagnetic field on the chick embryo chorioallantoic membrane on angiogenesis . JSSU. 2016; 24 (4) :317-328
URL: http://jssu.ssu.ac.ir/article-1-3611-en.html
Abstract:   (3419 Views)

Background and purpose:  Angiogenesis has a role in many vital processes also many developmental processes are influenced by an electromagnetic field. In the present study the synergic effects of silver nanoparticles and low-frequency electromagnetic field on angiogenesis in the chick embryo chorioallantoic membrane (CAM).

Materials and method: In this experimental study, (Ross strain ) on the eighth day incubation of embryonated chicken eggs were treated with 50, 100 and 200 mg/ml of silver nanoparticles. Then on tenth day, the eggs for 3 hours were exposed to the electromagnetic field. The twelfth day, the samples were photographed and the number, length of vessels, weight and Crown-rump were analyzed with software Image J. hemoglobin content were tested with derabkin assay. Silver nanoparticles antioxidant activity was assessment. Data were analyzed using spss 16 software and ANOVA statistical test.

Results: The average number and length of vessels and hemoglobin content decreased in treated groups with silver nanoparticles and Electromagnetic fields. synergic use of silver nanoparticles and Electromagnetic fields reduce the average number and length of vessels and hemoglobin content  than using one alone. Antioxidant assay showed that silver nanoparticles inhibited free radical production.

Conclusions: Synergic application of biogenic silver nanoparticles with electromagnetic field significantly reduced angiogenesis CAM comparing to use one of them. 

Full-Text [PDF 4292 kb]   (745 Downloads)    
Type of Study: Original article | Subject: Biology
Received: 2016/02/7 | Accepted: 2016/05/14 | Published: 2016/10/9

Add your comments about this article : Your username or Email:
CAPTCHA code

Send email to the article author


© 2018 All Rights Reserved | SSU_Journals

Designed & Developed by : Yektaweb